Meth Protecting Your Brain From the Harm Done By Meth Use

[Allylbenzene]

I'd recommend looking into progesterone also, it's one of the most potent anti-cortisol things the body makes (see picture below). It's also neuroprotective and will help a great deal in restoring coherent metabolic function. I got some bioidentical progesterone for my mum from an American company (I live in England), the ingredients are:

• Natural plant derived progesterone approximately 6 mg per drop;
• Natural d-alpha tocopherol &/or mixed tocopherols (vitamin E) 4-22 mg per drop; 12-66 mg per serving
• Other Ingredients: Organic coconut triglycerides

 

[red22]

I've heard of using pregnenolone but not progesterone. Your chart indicates that pregnenolone converts to progesterone in the body—why the preference for progesterone?

 

[emkee_reinvented]

Isn't ephedrine, available from the pharmacy over the counter with ID, a better suggestion? Ephedrine can actually be used to make meth…

Probably not, and it will not fall well estimation.
Its way down the pyramid, when young i tolerated it,
along no access to Speed. Khat/ Cathinone way better.

But when used to Meth, and protecting the brain question.
This is shit advise. Just based on the effect s of Ephedra extract.
Avoid. like Coffee, energy drink or caffeine pill. Abstain.

Take Matcha, Guarana or Mate, for Caffeine. Just a tip.

 

[Allylbenzene]

I am supposed to start easing into Wellbutrin SR & Naltrexone---which I feel will very likely help with stopping as well. The SR will be 100 at first, then they are working up to 400 and 50 mg of Nal at first working to 100.

So the common name for Naltrexone is LDN aka Low Dose Naltrexone.

B.C. Women's Hospital & Health Centre
27 Jan 2025
LDN doses range from 0.5 mg to 9 mg per day

Here's someones report on Naltrexone dosage:

Naltrexone: i took a 50mg pill and cut it into 4 equal pieces. Taking a full 50mg pill made me feel weird and sleepy but also anxious. Taking the widely discussed 4mg dose had a good effect initially but it wore off after a couple of days. The quarter of 50mg pill gave consistently good results like intense warmth over the entire body, calm mind, improved energy.

I'd start with something like 5mg, not 50mg!

 

[theangryflower]

So the common name for Naltrexone is LDN aka Low Dose Naltrexone.


Here's someones report on Naltrexone dosage:


I'd start with something like 5mg, not 50mg!

Oh wow....my doctor is prescribing me with 50 mg every other day at first then working up to 100 MG I believe within 1 month. O.O

Also, Wellbutrin SR ----starting at 100 mg 1 per day, and moving up to 400 MG within a month. (which also seems high....)

 

[Allylbenzene]

Wow, that's pretty high. I get that there are "standard dose sizes" but this isn't a one size fits all, especially for Naltrexone. Did your doctor not mention anything about starting with low doses?

If the Naltrexone is a tablet you can break it in half (25mg each) then half again leaving you with 4 pieces of roughly 12-13mg. For your first few doses you can nible half of a piece. See how you feel after the first few doses and take a bit more if you feel it (trust your intuition).
Here's a pic I found on Naltrexone dosing. I realise it's for "low dose Nal" but just to give you some idea of how that goes.

I am supposed to start easing into Wellbutrin SR ... SR will be 100 at first, then they are working up to 400...

I made this so you can visualise what Wellbutrin is in relation to meth (in yellow).
Meth does a few things but mainly increases noradrenaline and dopamine. It also inhibits MAO like the older antidepressant drugs. Wellbutrin mainly increases noradrenaline.

 

[red22]

Is it true that you can get an amphetamine-like effect from it if you IV it? If so, what's so special about that ROA?

Is it true that it's otherwise worthless junk that only has a faint effect even in therapeutic terms?

 

[Them Witches]

In short the answer your looking is to not do meth. So far it has proven to be the best available option to protect the brain and wallet against meth. It helps keep family & friend relationships going and growing.

 

[KurtAurelius]

I’m not sure how much I will be adding to the discussion.. alas

Stimulants need to be used regimentally if using daily, better yet to take time of if you can manage to, but fine if not:

Clinical Methamphetamine I believe is used at a maximum of 25mg pure Dextro Isomer Daily. This may be the amount studied that doesn’t not present neurotoxicity etc.

I don’t have any evidence for this statement, but I believe many are preconditioned to believe is many pegs higher than any other stimulants in damage.

There may be data regarding its neurotoxicity, the sertotonin affinity, and the clear fact that used above a threshold provides very compulsive and addictive effects.

But I’m not so sure in saying far beyond Amphetamine, MDMA/MDA, Cocaine and Cathiones, just a few important factors to consider,

If I was you, my only concern would mainly be the quality of what I was using, and also to bear in mind Methamphetamine has a established potency exceeding Amphetamine and is far more Soluble in the brain (I can’t spell Liphophillic or whatever it is)

Leading to the longer duration, potency and also observed neurotoxicity when heavily abused- my point here also remembering this is abusive high doses, no sleep, no self care, no food, etc. it has proven efficacy in medical use.

Of course yours won’t be “official” and that’s the gamble you take.

I would Volumetrically dose or capsule maximum 30mg to account for the unknown strength of product or if it is racemic.

I would dose only once in the morning, if not only a couple hours after if needing longer cover, say 7am and 9am if one dose doesn’t last all day. And this must only be in the safe range.
Going beyond risks all the utility in the first place.

You need to exercise, walking and weights is best bang for buck. Nothing crazy but 10,000 steps 3x a week, and 2 30 min full body work outs will suffice.

Protein every meal, sensible carbs and fats, fruits and veggies. If you struggle to eat healthy and it’s not a appetite issue then you can supplement but it’s not a excuse to avoid all whole and quality foods.

From the dosing regimen, I could be wrong as I can’t think of methamphetamines half life, but if possible to allow it to clear overnight as you sleep, as this will ensure your receptors, monamines etc has a chance to clear, repair and rest.

I’d also recommend very specific potent antioxidants/other helpers that don’t have issues like NAC- it’s a god send but it takes baby sitting.

These being

Benfotiamine
Tocotrienols
Taurine
Creatine
Astaxanthin
Magnesium L Theronate
Vitamin D3 in the 2000IU range
Vitamin K2
Lmethylfolate

I can do a write up but these have specifity in assisting what may come as the toll of chronic stimulant use at medical doses.

Lastly sleep, it beats everything, but making it as good as possible and quality will help everything else, my Methylphenidate is a different drug depending on how well I’ve slept.

 

[Allylbenzene]

Creatine

Funnily enough creatine has potential as an antidepressant similar to the prescription antidepressant ketamine.
Both agmatine and creatine protect from stress.

This is quote on creatine from research looking at the theraputic potential of agmatine, creatine, guanosine & ascorbic acid.

[An] investigation of the possible role of endogenous glutamatergic neuromodulators for fast antidepressant responses - agmatine, creatine, guanosine, ascorbic acid.

In view of the results which show a similar effect between creatine and ketamine...
...
Interestingly, a single creatine administration was able to reverse cortisol-induced depressive-like behavior...
...
This evidence suggests that creatine could share with ketamine the ability to promote a fast antidepressant-like response.
...
These studies suggest that creatine could present a faster antidepressant effect when compared to conventional antidepressants...

https://journals.sagepub.com/doi/10.1177/2470547019858083