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propylhexedrine

ebola?

ebola?

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Hello all.
I know these questions aren't too "advanced", but I wasn't able to get any responses in OD.

1. Does anyone have data about ph's receptor affinities on hand, both in terms of binding and release for the different monoamines? A comparison to more common stimulants would be nice.
2. Does anyone have proper quantitative research comparing the potency of ph to other, more common stimulants? Preferably, we'd want these potencies to be anchored in anorexic effects in experimental animals, right? On the other hand, these animals rarely eat the drugs their given.

ebola
 
You would think with how long its been around; this kind of info would be easy to find. I'll run it through pubmed, pubchem and medline tommorrow.
 
I can't find any binding data in regards to propylhexedrine...

It must be out there, I will look at school.

Do people find PHX more enjoyable than l-methamphetamine?
 
^ Sadly no - they ended up being an admission to a Glasgow A&E dept. Then again this is a city where te favourite opiate of abuse was recoded as being buprenorphine, not heroin or anything like that (& it wasn't a matter of availability, they acttually liked buprenorphine over heroin 8o )
 
I've heard of people liking Thorazine (chlorpromazine).
I think 2Pac has a lyric, "These streets got me cravin' Thorazine."
 
This lady I used to work with used to tell me about getting out of work early so she could take her seroquel and pass out.

she also had two quasi retarded children, so maybe that was the impetus?
 
>>Do people find PHX more enjoyable than l-methamphetamine?>>

Should I even bother with l-meth? I just thought that it was a bunch of jitters. As it stands, ephedrine is way too jittery for me.

>>A million times over.>>

Well over. 0*1000000=0. :)
...
I'm doing a cursory pubmed search right now.
Evans and Johanson (1987) suggest that PH substitutes unreliably for AMP in AMP trained pigeons at 5 to 50 times the amp dose at which they were trained (2 mg/kg).

Wesson (1986, Symposium paper) argues that PH substitutes for AMP in people with a history of abuse of the latter, but such people prefer all types of AMP salt preparations over PH.

Plenty of articles saying that IV PH could kill you and has killed others. :)

1 article showing long-term cardiotoxicity in a subject who took PH for 8 years as an anoretic.

ebola
 
Well, l-meth is around 3/5ths the potency of phentermine in regards to dopamine release, and roughly 1/3rd in regards to uptake. Otherwise it is somewhat similar, but then again, from what I gather, most people don't enjoy phentermine much.

Maybe PDX would be somewhat similar to phentermine (or in between l-meth and phentermine), perhaps slightly more serotonergic, but I really have no idea...

What "doses" do people take of PDX? I would imagine there would be quite a bit of side-effects with a dose high enough to produce significant CNS stimulation...
 
Propylhexedrine is nearly as good as a combination of ephedrine and d-methamphetamine to me. The peripheral effects are too strong to take a dose that would rival high dose methamphetamine for generating euphoric feelings... but at reasonable doses, it feels just like a small dose of amphetamine or methamphetamine combined with a large dose of ephedrine. Very very pleasant.

If only it wasn't mixed with lavender oil and embedded in cotton when purchased OTC... I'd use it regularly.
 
As far as dosage, negrogesic, whatever comes in a single Benzedrex inhaler is a great dosage for oral administration. Lasts for a long time too, way longer than amphetamine... not as long as methamphetamine though.
 
>>Well, l-meth is around 3/5ths the potency of phentermine in regards to dopamine release, and roughly 1/3rd in regards to uptake. Otherwise it is somewhat similar, but then again, from what I gather, most people don't enjoy phentermine much.>>

Intriguing. I'll have to look up binding data on phentermine (haven't tried it) and make an evaluation.

>>
What "doses" do people take of PDX? I would imagine there would be quite a bit of side-effects with a dose high enough to produce significant CNS stimulation...>>

Well, from the erowid reports, most people take 250 mg to 500 mg. Most all of the 500 mg people report that it's "too much", and a healthy few of the 250 mg people reporting a high incidence of negative side-effects.

This guy took 125:

http://www.bluelight.ru/vb/showthread.php?t=381911

ebola
 
Propylhexedrine is nearly as good as a combination of ephedrine and d-methamphetamine to me. ... but at reasonable doses, it feels just like a small dose of amphetamine or methamphetamine combined with a large dose of ephedrine. Very very pleasant.
Click to expand...

Pleasant is the last word I'd use to describe any sort of dose of l-ephedrine beyond a very small bronchiodilating dose due to the peripheral sympathetic effects as ephedrine is a directly acting compound unlike amphetamine, methcathinone, diethylpropion etc (avoid directly acting sympathiomimetics unless you think tachycardia & uncontrollablr, stinky sweating fun with a fine motor tremor!
 
I don't get tremors. I get the sweating and the feeling of my hair tingling and growing, and my skin feels somewhat like it does on MDMA but much milder. Ephedrine is a pretty pleasant drug for me.
 
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