Propylhexedrine Derivatives

[nAON]

Would any of these be active? I would think there could be many propylhexedrine 'equivalents' of PEAs. I know at least a few people have been talking about a propylhex version of MDMA, with the structure the same except for cyclohexane replacing benzene.

Would any of them actually be active, and if they are, how feasible would it be for them to be used recreationally?

 

[ebola?]

This topic has been discussed a number of times here. Please try a search.

But in brief, these compounds wouldn't be too promising, given that they would be far lower potency, highly adrenergic versions of their phenyl ring homologues (this is by analogy of comparison of phex w/ meth).

ebola

 

[nAON]

I tried searching around, ended up getting loads of results, checked couple pages but couldn't find anything specific. Will take another look^

 

[sekio]

The cyclohexyl ring is far too bulky to have good interactions with DAT/NET. The other problem is that since cyclohexane is not planar, it's another set of chiral centres for every ring substitution.