• N&PD Moderators: Skorpio

Propylhexedrine and MDMA Similarities

fullthrottle3360

Greenlighter
Joined
Dec 6, 2008
Messages
1
Has anyone who has tried propylhexedrine noticed strong serotonergic effects (in comparison to, say, amphetamine)? Most people compare the feeling on it to amphetamine but I just can't help noticing that it feels much more like an empathogen. In addition, the crash is accompanied by migranes and flushing, a good sign of serotonin playing a role there... I was thinking that maybe the reason that more people haven't felt this way is because of the poor absorption through the blood-brain barrier, so most people just feel the peripheral effects of racing heart and speedy jitters.
 
I know exactly what you mean - I did 500 mg's and I noticed extreme serotonergic effects, and it felt a whole lot like mdma more so than it did amphetamine

In comparison one time I took only 250mg's and it felt like your standard dopamine/norepinephrine cns stimulant and since I have adhd it just made me really calm and quiet and a little bit paranoid, unlike the 500mg which made me talkative and gave me a really loved up feeling
 
Last edited:
I believe that it's marked adrenergic agonism coupled with serotonergic effects likely in the same league as meth effect the compound's distinct tactile enhancement.

ebola
 
Yes, it almost definitely releases serotonin. It feels like a meth bomb MDMA pill at ~325 mg for me. Occasionally it's strong enough to make my vision all liquidy and cause stumbling.
 
^Careful, the reason I think I can dose that high without issues is because my BBB seems to be more permeable to it, so more of it goes to my brain. Even so, I sometimes get stiff hand muscles from the vasoconstriction by the end of the night. A fantastic combination drug with it is low dose aMT. It lengthens the peak and increase the euphoria. I've also thrown in ~75 ug of LSD on top of that combo to even greater increased euphoric effect ("Whoa, I need to just sit here and smile for awhile" strong). I eat sugary stuff throughout and can usually largely avoid any significant crash this way (aMT helps greatly with avoiding a crash by smoothing out the monoamine drop-off, too). Coca tea also works good to avoid a crash.

The only time I had a problem was when I added 1, 3 dimethylamylamine to the aMT and propyl (75 mg) to test if it could function as a cheap potentiator. I ended up with a crippling headache from increased blood pressure for about an hour. The next day at the gym the headache returned while I was doing pull-ups. So definitely avoid DMAA.
 
You guys indeed take startlingly large doses. I wouldn't be able to tolerate persisting adrenergic effects if I were to take more than 250 mg.

ebola
 
You guys indeed take startlingly large doses. I wouldn't be able to tolerate persisting adrenergic effects if I were to take more than 250 mg.

ebola

And, for you, if I recall, this is 250mg spaced out over the course of a few hours or more, right?

Speaking of, I get the same effects. I find propylhexedrine to be very tactile-enhancing and definitely pro-sexual. When combined with nitrous oxide, there are fleeting moments where I really do feel like I've taken good MDMA, as far as the nitrous effects last at least. By itself, it definitely has its own character, but it's still somewhat edgy (that damned adrenergic push).
 
I don't know how anyone uses this stuff. I did notice tactile effects and somewhat of a euphoria the first time I used 250mg, but after a few hours of feeling good I developed the worst headache of my life and was forced to retreat to bed. All night long I felt delirious, nauseous, and suffered from the thudding severe headache.

I tried smaller doses twice after that and always just felt sick from the stuff, I never felt euphoria for very long before I felt outright dysphoric. The 3rd and final time that I took it I puked up menthol-flavored bile when I got up for work the next day. The vasoconstriction was always too much for me I guess.
 
Top