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Pricetam Dosing question

thizzlam

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Feb 15, 2011
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So i started taking pricatem around 1600 mgs twice a day to help my brain recover from using mdma weekly for quite some time. Is this the correct dose?
 
There is no "correct" dose, but I think 1600 mgs is a good dose. I typically pre-load with 800-3200 mgs, so you're at a reasonable, helpful amount.
 
Piracetam has in a number of studies shown itself to be well tolerated with a very low toxicity. Figure out a dose regimen that seems to work for you. Play with when you take it whether its when you wake up, with meals, before bed, etc.

This isn't the board to get all into nootropic discussion in its general nature, but there are a number other things that facilitate its action. Nootropics and more specifically the racetam are a very fascinating rabbit hole. The next link is basically just a list of all the other relatives of Piracetam, many of them with great effect/side effect profiles for cognitive improvement. Do some research into them, its quite fascinating. 'it will help you to figure out what parts of the brain your playing with and you can figure out how to make it work better. A healthy diet and certain supplements, enough sleep, and doing activity that engages the mind in conjunction with these types of compounds should improve your memory over time. It might take time and you might not feel much different, but try to get a feel for how many fewer spacy moments you have.

http://en.wikipedia.org/wiki/Racetam

This is an interesting read, not necessarily one that is applicable at the present moment, but the possibility of mice with the ability to remember anything they see for a period of up to 14 months as opposed to an hour resulting from an over-expression of RGS14 is kinda fascinating when you realize that we also exhibit this gene that seems to have a profound effect on our ability to remember what we see....

http://www.alzforum.org/new/detail.asp?id=2182

Fascinating stuff though, compared to piracetam this sort of mechanism is pretty unexplored. There are a number of other derivatives that have differen't water vs lipid solubility. Some of them are a lot more immediate with shorter duration and others take days of taking it before you notice its effects but they stick around in your body longer.

I have not personally taken piracetam, but I believe it has a build in tolerance over time, I am not the one best suited to explaining these compounds but some of the things I do know is that your body with utilize it more effectively with a choline supplement.

If you experience a headache from taking piracetam, a choline supplement should be taken.

Look into hydergine and there are about a thousand others.

http://en.wikipedia.org/wiki/Levetiracetam
Speaking as someone that has taken this one as a prescription medication for its anticonvulsant action I felt that I would give my thoughts on it. I was supposed to double the amount I was taking at 2 weeks. Long before I reached that point I encountered quite a lot of its side effects despite being considered "well tolerated". Nothing about my body or mind liked this one in the least bit. From the pharmacy, before insurance the cost on enough for a month was something like 700 dollars per bottle.

Levetiracetam is, in general, well tolerated[6] but may cause drowsiness, weakness, unsteady walking, coordination problems, headache, pain, forgetfulness, anxiety, irritability or hostility, dizziness, moodiness, nervousness, loss of appetite, vomiting, diarrhea, constipation, and changes in skin color.

Im normally a pretty chilled out person, but I realized that I couldn't keep taking this much less take twice what I had been after I found myself hauling ass down the interstate at 90 miles per hour barely maintaining consciousness at the wheel while exhibiting dangerous levels of road rage for even the slightest thing. Massive dysphoria, irritability, hostility, aggression, it was hard to keep food down and nearly constantly dizzy.
 
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There are quite a number of ways to make some parts of this process work more efficiently.
http://oi54.tinypic.com/bgpu6f.jpg

I would aim at a reduction in the breakdown of 5-HT by Mono Amine Oxidase by taking saint johns wort as it reportedly has an maoi action..

The next one acts as an inhibitor of the conversion of 5-HTP into 5-HT. While the idea might seem paradoxical at first, you have to realize that serotonin last literally a minute before the MAO breaks it down. So its a drug that allows you to accumulate 5-HTP in your blood, but because 5-HTP can get across the blood brain barrier but the inhibitor can't, the metabolism into 5-HT is then carried out in the brain where it can be utilized more effectively instead. I have no idea what sort of side effects this drug has, im just explaining a point. B6 seems to interact with the enzyme that turns 5-HTP into 5-HT.

http://en.wikipedia.org/wiki/Carbidopa

This is a form of folate that can get across the blood brain barrier and at least this says that it helps stimulate the production of serotonin, epinephrine, and dopamine. leaving out the carbidopa....

Do not believe for a second that this has no ability to be dangerous, i have spent a while looking up stuff for you to do personal research into. If you were to start a regimine of saint johns wort, 5-HTP, L-methylfolate, and a couple hours later eat a B6 tablet or two I feel like it would probably stimulate serotonin production, possibly to the extent of causing serotonin syndrome which can kill you. I would leave out the st. johns wort at first just to see how your body tolerates it.
 
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Regularly taking Piracetam will definitely result in a tolerance build-up (like with any substance). As far as I know, Piracetam doesn't actually restore your serotonin levels, it simply helps remove the drug induced fog from your mind. 5HTP is what you should be researching if you want to restore your levels of serotonin.
 
What makes you think you need to restore your serotonin levels out of interest?

because I no longer feel the MDMA... does not feel the magic...if I take a pill of ecstasy, I just yawn...my dose of crystal MDMA to feel something has got to 450 mg... if I sink below 350 mg did not hear anything...using MDMA for 15 years
 
That could just as easily be straight forward tolerance, brain rewiring and the general down-grading in quality over the last decade.

Obviously abstinence for several months is a good bet. Piracetam is fabled to bring the old magic back a bit.

How often do you do it?
 
I advise you to do more research. It will be much more useful for you to just go out and figure out how your brain works before you go and tinker with the inner workings of it.

Overuse of MDMA is generally considered to cause some receptor downregulation from overuse.

Have you thought about just taking a break, like one in excess of a year or more?

I think your chasing a dragon that your brain can not keep up with.
 
I definitely need a break, and that is what i want to do ... and during this break I want to try the 5htp + piracetam ...

you have any other advice for me? or some other substance to be added to restore the levels of serotonin?
 
Piracetam isn't likely to harm you so feel free. It's not going to do all that much in my experience. I personally cannot tell the difference in my daily life other than increased headaches. I'm yet to use it as a pre-load for MDMA so maybe it's more powerful like that. It's not going to restore the supposedly low levels of S you think you might have. 5htp might help a bit. St Johns Wort might. SSRI's might. Stablon might help. Some of them might makes things worse. Personally I wouldn't touch ssri's unless I was depressed and there were no good other options. I've been on them and they're horrid.

The two you've mentioned are pretty benign so see what happens.

Thing is, let's say you actually do have low levels of serotonin. It's not like you can just pop a few pills and "reset" it. If you push the production up your brain will likely uprate the reuptake. If you slow reuptake it can lower the production and so on. it's hideously complex.
 
Question, if you guys could answer quick that'd be awesome. Been on 1600mg piracetam and choline for the past 4 days... about to roll in an hour or two. I tested the molly im about to take (marquis and mecke) both positive reactions but I heard it was kinda weak from friends who took it. would bombing 250-300 mg at once be too much while on piracetam? I usually eat about a 500mgs of mdma when I roll. thanks so much!
 
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