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  • BDD Moderators: Keif’ Richards | negrogesic

Gabapentinoids Pregabalin weird side effects help.

Okiv99

Bluelighter
Joined
Oct 8, 2024
Messages
33
Hi I have been experimenting with pregabalin a little bit and seemingly get no high (even my first time using it) and just get brain fog/feel slightly more relaxed. But additionally it seems to give me a bloated face. Is this a normal symptom of using it? Or could it be I have kidney damage and when I use this it is the straw that is breaking the camels back so to speak.
 
@Okiv99 hey buddy. Yes, fluid retention is a side effect that has been observed when Gabapentinoids like Pregabalin (Lyrica). I notice it in my hands sometimes, though it's not anything to worry about if it's an isolated issue. It's just a side effect. It doesn't imply that there is something wrong with you.

Do you have issues with your kidneys? Unless a doctor has told you that you have kidney problems, then you'd be better off not to even think like that. It's only going to drive you crazy.

I'm not sure how much Pregabalin you're taking. For inexperienced users, 300mg-600mg is the best place to start. If I were in your position, I'd take ~450mg before waiting at least a few hours before taking anymore. These dosages should be enough to give you a good experience without a lot of risk.

I wouldn't exceed 600mg Pregabalin though. It's not particularly dangerous. However, in higher dosages, it is known to produce convulsions and myoclonic seizures. I have had this happen to me. There were a couple of times that Pregabalin made me flail so badly I had to lay down or I would hurt myself. With all that in mind, just be responsible about the dosages.
 
@Okiv99 hey buddy. Yes, fluid retention is a side effect that has been observed when Gabapentinoids like Pregabalin (Lyrica). I notice it in my hands sometimes, though it's not anything to worry about if it's an isolated issue. It's just a side effect. It doesn't imply that there is something wrong with you.

Do you have issues with your kidneys? Unless a doctor has told you that you have kidney problems, then you'd be better off not to even think like that. It's only going to drive you crazy.

I'm not sure how much Pregabalin you're taking. For inexperienced users, 300mg-600mg is the best place to start. If I were in your position, I'd take ~450mg before waiting at least a few hours before taking anymore. These dosages should be enough to give you a good experience without a lot of risk.

I wouldn't exceed 600mg Pregabalin though. It's not particularly dangerous. However, in higher dosages, it is known to produce convulsions and myoclonic seizures. I have had this happen to me. There were a couple of times that Pregabalin made me flail so badly I had to lay down or I would hurt myself. With all that in mind, just be responsible about the dosages.
Tbh i have been a bit reckless with it i took 600mg initially and didnt get much of an effect so then i took another 900mg now no shakes or anything just tired and my balance is off. Im wondering does it have a cross tolerance with benzos? maybe becacuse me benzo tolerance is so high (I can take 10mg xanax and work out/function normally) im not feeling the pregabalin much.#

I definitely dont have any euphoria like ive heard some people get.

Do you know if they have a cross tolerance?

Also do you know if eating after taking it has any effect? Sorry for all the questions.
 
Tbh i have been a bit reckless with it i took 600mg initially and didnt get much of an effect so then i took another 900mg now no shakes or anything just tired and my balance is off. Im wondering does it have a cross tolerance with benzos? maybe becacuse me benzo tolerance is so high (I can take 10mg xanax and work out/function normally) im not feeling the pregabalin much.#

I definitely dont have any euphoria like ive heard some people get.

Do you know if they have a cross tolerance?

Also do you know if eating after taking it has any effect? Sorry for all the questions.
In theory, there is no cross tolerance because pregabalin has a totally different mechanism of action than benzos. Some users say they never noticed it and some say they have.

Are these meds prescribed to you or someone else, or were they purchased online? And what else are you taking?

Also, food decreases the rate of pregabalin absorption which lowers the cmax around 30% and increases tmax to around 3 hours.

I always take it in a fasted state
 
Hi I have been experimenting with pregabalin a little bit and seemingly get no high (even my first time using it) and just get brain fog/feel slightly more relaxed. But additionally it seems to give me a bloated face. Is this a normal symptom of using it? Or could it be I have kidney damage and when I use this it is the straw that is breaking the camels back so to speak.
All I get is brain fog and loss of motor control from pregabalin. It is not remotely recreational for me. But, it can be helpful for neuropathic pain and I find it’s not too cognitively impairing at low doses. It’s still noticeable, but I’m able to get things done.

Not everyone finds it recreational. I don’t find any downers recreational. I don’t think crossed tolerance is to blame in your case, but we don’t yet fully understand how it works so it’s not impossible.
 
In theory, there is no cross tolerance because pregabalin has a totally different mechanism of action than benzos. Some users say they never noticed it and some say they have.

Are these meds prescribed to you or someone else, or were they purchased online? And what else are you taking?

Also, food decreases the rate of pregabalin absorption which lowers the cmax around 30% and increases tmax to around 3 hours.

I always take it in a fasted state
Bought online also bought 50a xanax. Thought id use the pregabalin while i was coming off kratom but kinda binged on it.
 
All I get is brain fog and loss of motor control from pregabalin. It is not remotely recreational for me. But, it can be helpful for neuropathic pain and I find it’s not too cognitively impairing at low doses. It’s still noticeable, but I’m able to get things done.

Not everyone finds it recreational. I don’t find any downers recreational. I don’t think crossed tolerance is to blame in your case, but we don’t yet fully understand how it works so it’s not impossible.
Yes i get the same as you. No euphoria what so ever just brain fog and kinda dizzy.. I love downers though bbenzos and even kratom i love. Taking 25 grams at once.
 
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