Potential to make ultrapotent MDMA like Ergot derivetives

[BilZ0r]

Not all 5-HT or DA releasers are neurotoxic.

3-Methoxy-4-methylamphetamine
5-methoxy-6-methyl-2-aminoindan
http://www.ncbi.nlm.nih.gov/sites/e...dan analogues of nichols&tool=QuerySuggestion

P.S. Sticking a big molecule onto MDMA is seriously going to fuck with it's ability to be a substrate for SERT and DAT, and hence it'll be an uptake blocker at best.

 

[nuke]

Not all 5-HT or DA releasers are neurotoxic.

3-Methoxy-4-methylamphetamine
5-methoxy-6-methyl-2-aminoindan
http://www.ncbi.nlm.nih.gov/sites/e...dan analogues of nichols&tool=QuerySuggestion

P.S. Sticking a big molecule onto MDMA is seriously going to fuck with it's ability to be a substrate for SERT and DAT, and hence it'll be an uptake blocker at best.

I was just joking, but I mean, suppose you could stick something lipophilic and neuroprotectant on it that could be easily hydrolysized off? You'd be left with an active neurotoxin and a neuroprotectant, with the hope that they'd even eachother out.

Also, I can't find anything in the abstracts of those papers that indicate those compounds to be DA releasers? Do you have full-texts of them?