Potency of 2c-d sulfate

[Shakti]

I think this is the right forum, but for many of you it wont be very advanced at all.

I was wondering what the relative potency of 2c-d sulfate is compared to 2c-d hcl. I calculated it at approximately 95%, but I don't fully trust myself on this one. It would be great if one of you chem whizzes would help me out.

Thanks!

 

[UnfortunateSquid]

It'll be damn near the same.

 

[nuke]

It's slightly less potent, I would probably dose about the same.

 

[yaesutom]

2c-d sulfate's molecular weight is 293.34 and 2c-d hcl is 231.72, 231.72/293.34=0.79 so the sulfate is about 79% as potent as the hcl... if i did that right (?). If so then 100mg of the sulfate would equal 79mg of the hcl.

 

[UnfortunateSquid]

The sulfate ion has a 2+ charge, so there are two 2CD cations for each sulfate anion.

This means the actual molecular weight is ~245, hence there being a minimal difference in potency - the OP's estimate of 95% is accurate.

 

[tryp2fun]

The sulfate ion has a 2+ charge, so there are two 2CD cations for each sulfate anion.

This means the actual molecular weight is ~245, hence there being a minimal difference in potency - the OP's estimate of 95% is accurate.

The sulfate ion has a -2 charge. That's how you get two ammonium cations for each sulfate. The apparent molecular weight of the amine of 2C-D sulfate is 242.28 and the hydrochloride is 229.73. Thus, the hydrochloride is 229.73/242.28 = 1.055 times more potent by weight.

 

[Shakti]

Thanks for checking my work guys

 

[UnfortunateSquid]

^^Err that's what I meant, I was drunk

Same difference though