• 💊 OTHER DRUGS 💊 Welcome Guest
    Posting Rules Bluelight Rules
    Notable Threads 1 Notable Threads 2
    Dangerous Combos Addiction Support
    Emergency Services Benzo Guide v.1
    Addiction Stories Scary Case Studies
    Biology, Pharmacology & Drugs 101
  • Select Your Topic Then Scroll Down
    Alcohol Bupe Benzos
    Cocaine Heroin Opioids
    RCs Stimulants Misc
    Harm Reduction All Topics Gabapentinoids
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums

RCs Possible MDPV replacement: 3,4-dimethoxy-α-PVP (DMPV, DMPVP)

Halif said:
^ I fucking hate it when vendors only sell ultra potent stims in minimums of 10 grams, when all you want is ONE gram, or just a sample.

it's dangerous for the potential user both in terms of them overusing, and in terms of being caught with an amount of something which could qualify in some places as a commercial quantity...
Click to expand...
What Tryptamite said! Then again, they are usually so damn cheap that it's still a bargain purchasing 10g and throwing 9900mg away lol.
 
Do we really need another MDPV or A-PVP in the world? I mean all these analogues will probably just have worse and worse side effects and a less satisfying high...
 
Indopan said:
I have had plenty of euphoria from a-PVP. The problem in most cases, as I think, is, that people use too low dosages and as these drugs are very compulsive they keep binging for days in a row, get no euphoria, but still panic attack or even worse could be psychosis. I did it in larger dosages for about 10-12h and then after 2-3h went to sleep. By the way, it can make your heart faster at 10-15mg, but 30-35mg killed the anxiety and my heart rate was within safe range. At the end of the day my heart rate was about 100-110. I still would not recommend trying 30-35mg as the first dosage. I could have had different reaction from other people and maybe this is why I like it. (well it really was my first dosage after allergy, which was 5mg, maybe some more)
Click to expand...

I have found the same things with PV's and me
 
cyberius said:
Do we really need another MDPV or A-PVP in the world? I mean all these analogues will probably just have worse and worse side effects and a less satisfying high...
Click to expand...

Amen! Anecdotally and through experience, I find that the amount of people that like PV's is pretty small. I also find it unlikely that they're going to get better and better analogues. My 2 cents
 
cyberius said:
Do we really need another MDPV or A-PVP in the world? I mean all these analogues will probably just have worse and worse side effects and a less satisfying high...
Click to expand...
I think we should legalize amphetamine for recreational use already so at least people will know what they're taking and won't have to buy all this bath salt crap to avoid breaking the law*.

*which is not even a guarantee.
 
bennyZA said:
Of course, but our stupid prevailing world view is that drugs are bad... m'kay. It will take some time, but as more and more countries realize legalization is better than criminalization more and more will follow suit.
Click to expand...
Meanwhile, the same people are hooked on xanthines, alcohol, and tobacco, the latter two of which are dangerous drugs on par with many illegal and prescription ones.

I think that says something about our drug education.
 
Since I could not find valid information about this material
on wiki,PubMed etc,I checked psychoactive substances which share the same structure (3,4-methoxy ) at benzene ring,and
three phenethylamine class drugs were hit (at wiki.).

Here are them.
1) Dimethoxymethamphetamine(DMMA),
2) 3,4-Dimethoxyphenethylamine(DMPEA)
3) 3,4-dimethoxy-beta-hydroxyphenethylamine(DME)

The first one says it acts as serotonin-norepinephrine-dopamine releasing agent and has weaker potent than MDMA.
I have checked a linked paper,
But no further information I could be found.

The second document is also almost PiHKAL citation.
At 1000mg oral,nothing has come at all.
And it says that it may have though some MOI potential.

And last one whose content also cites from PiHKAL says
that after over 100mg oral,nothing has come.

Summing up this information, ( I can say nothing exactly About it though ), I can have a little guess that It may be far from (or maybe very weaker than) MDPV. And it may have some hallucinogenic properties, Because Mescaline also shares the same structure.

Phenethylamine and pyrovalerone analogs both share similar Properties in some aspect. At the first shot, pyrovalerone analogs Give us a nice euphoria, but using it a lot a day for more than A week, no one can avoid developing schizophrenic symptoms. I think Amphetamine and methamphetamine analogs, at this point, have much more good profiles.

But the same modification of each benzene ring seems to show similar pharmacological effect. If more papers about 3,4methoxy extension of Cathynone or the phenethylamine class will be found, they will tell us much more about this chemical. ( I hate alpha-PVP which kept me to a closed hospital center For more than two months)

## This is my first post here.
## I feel very sorry for my poor rough English and
## if I am breaking this forum's rules. Please point it out strictly.
## Thank you.
 
ebola? said:
Why would you expect this?
...
Why would we want ever closer analogues of a shitty stimulant like MDPV? Sure, people dose on it compulsively, but it has a pretty shitty effect-profile.

ebola
Click to expand...

I would suspect neurotoxicity based upon the likely metabolism to a 3,4-dihydroxy compound. Dopamine analogues like this often act as dopaminergic neurotoxins. Even the simple alpha methyl dopamine. I liked a-PVP way back before they ever sold it online, it's not horrible like some people make it out. Better than benzphetamine or any of the weaker prescription amphetamine types. I only had pyrovalerone a couple times after finding some from the sixties or seventies while cleaning out a relatives home. It was pretty similar to a-PVP.

With all of these new stimulants coming out, I'd like to see someone do a blind administration and see how many can actually tell them apart.
 
Last edited:
Hammilton said:
I would suspect neurotoxicity based upon the likely metabolism to a 3,4-dihydroxy compound. Dopamine analogues like this often act as dopaminergic neurotoxins. Even the simple alpha methyl dopamine. I liked a-PVP way back before they ever sold it online, it's not horrible like some people make it out. Better than benzphetamine or any of the weaker prescription amphetamine types. I only had pyrovalerone a couple times after finding some from the sixties or seventies while cleaning out a relatives home. It was pretty similar to a-PVP.

With all of these new stimulants coming out, I'd like to see someone do a blind administration and see how many can actually tell them apart.
Click to expand...

Slightly offtopic, but what would this mean for the neurotoxicity of MDPV?
 
^ I fucking hate it when vendors only sell ultra potent stims in minimums of 10 grams, when all you want is ONE gram, or just a sample.
Click to expand...

Try vendors refusing to sell less than 5-10 mg of nbome compounds...no, I DON'T want to lay over 10,000 hits of blotter. :P

ebola
 
cyberius said:
Do we really need another MDPV or A-PVP in the world? I mean all these analogues will probably just have worse and worse side effects and a less satisfying high...
Click to expand...
No, we do not. What we need is something MUCH stronger!^^
 
Well, thanks for the answer for an annoying bump (bump the thread on top with a slight modification a la 'Any news?').

The comments on my current favs (call me philister) made me think like there must be better compounds for more accurate results. It is definitely dirty, when a 3g bag washes away in a week. No buying food, neither watch for mail, nor answer the phone (in the end). All the struggles with side-effects and the strategies I developed to overcome these.

I don't want to advance the discussion to other substances not mentioned in the thread title, but if anyone found an equivalent for his research, I'd be more than happy for a PM.

Cheers

EDIT: there is no PV-9 thread.. anyone seen one?
 
Last edited:
There should be DMPV testing this week that should provide us with some answers.

@smashpast, you talking about 4-MeO-PV9 or just PV9? Pretty sure I saw both.
 
@ThaDudeAbides, talking about PV9, as they seem just to number the new Valerones

would be interesting to discus results.
 
You must log in or register to reply here.
Top