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Possible drug interaction between Nardil and 2C-B

BillNye84

Greenlighter
Joined
May 20, 2010
Messages
6
SWIM recently got a prescription to Nardil (Phenelzine; a MAOI) and has been taking a low dose of it (15 mg) for 2 days now. At SWIMs college, there is a big party weekend with live music and lots of drinking on the 30th, and SWIM has been saving a hit of 2C-B for it. Now, SWIM knows that in all likelihood combining a phenethylamine with a MAOI will result in a terrible trip, and that the standard washout period for MAOIs is 14 days. Will he be fine if he stops taking the Nardil now and takes the 2C-B ten days from now? My gut tells me he will be, since the Nardil couldn't have built up that much in 2 days and interactions go away after two weeks even in people taking 90 mg a day, but I don't know for sure.
 
Greetings to you Mr. Science Guy!

First off, welcome to Bluelight!

Second, as I was told after my first post I will follow the tradition: No swimming in the deep end!
The term "SWIM" offers no more legal protection whatsoever than "I" and gets confusing and annoying. You can stop swimming here, it's all in the good spirit!

As for your inquiry, your ten day window should clear any risk of encountering serotonin syndrome if you've only been taking MAOis for a couple days. I highly doubt that there would be any significant amount of Nardil left in you by that time. Does anyone corroborate?
 
Well serotonin syndrome wasn't the main issue, it was just having a bad trip experience. If you ever read a report of someone taking selegiline with 2C-B you'd know mean. Anyway, on a different forum for anxiety someone recommended against it, but I think he was just airing on the side of caution. I can't imagine I'd have irregular MAO levels after 10 days if I only took two low dosage pills though.
 
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