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Opioids Plugging Methadone Sugar Free Liquid

Gaz_hmmmm

Bluelighter
Joined
Nov 27, 2002
Messages
4,108
Location
England, UK
Is plugging methadone (Obviously for getting high) better than oral? I know orally Meth' has a BA of about 85% and I know that most opi's when plugged are as effective as intramuscular injection.

All that's in the Methadone oral solution is 2 E colour's, parahydroxybenzoate and methyl-parahydroxybenzoate (These are natural preservatives, even if they don't sound it! I know they're found in apples or grapes, or both! :\ )

So is better then orally?

Also I'll be using Grapefruit juice too, since it'll eventually go to the liver!
 
i don't think taking methadone any other way that orally is beneficial to a high. maybe just a faster onset? orally, i believe, is the best way to take it.

but if i find any solid evidence about plugging methadone, i will try it with my next take home dose.
 
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It's probably a faster onset than orally; but not much different otherwise. M/done is well absorbed orally. It's a bastard of a molecule - really fat soluble and difficult to metabolise.

Just be careful with your dosing, you wouldn't want to overshoot.Wiki says the oral BA is anywhere from 40 to 90% orally. I imagine it depends a lot on whether or not you are a chronic daily user of 'done or not.
 
I plug my weekend bottles every now and then. I used to do it a lot more, but now constipation has caused me to not risk possibly wasting some of the methadone.

Anyway, if you're not backed up, plugging methadone is a great ROA IMO. I've injected methadone (micron filtered) in the past, and I swear to god that when you plug methadone it both hits you faster and harder. For those that aren't chronic users and are using methadone as a replacement of their DOC, its a good ROA to use as the oral onset can take three hours (versus the five minutes it takes when plugged).

As for comparing the BA/absorption to oral, rectal is actually about 10% less effective I've read (70-77%), ut the quicker and more intense meet makes up for it and some. I definitely think that (so long as your pipes are empty and your technique is correct) rectally administered methadone feels stronger and lasts longer, and though it may not make sense I find it ,more euphoric and anxiolytic.

I will note though, that I get my methadone doled out in a 10mg/mL solution. If you're dose is watered down to the point where you're dealing with 50mL or so, I don't think plugging would be advantageous. IME using more than 20mL of any liquid is kind of annoying and irritating.

And on one final note, you will get the best results if you lay on your side for ten to twenty minutes after you preform the sacred act.
 
Here's a study on it: Bioavailabilities of rectal and oral methadone in healthy subjects

The mean absolute bioavailability of rectally administered methadone was 76%, compared to 86% for oral administration. Rectal absorption of methadone was more rapid, reaching peak blood levels at 0.9-1.8 hours versus 1.6- 4.0 hours after oral dosing. Single rectal doses of methadone had a duration of action of at least 10 hours. The maximum blood concentrations reached with both rectal and oral were very close.

EDIT: Also it should be noted that they used an absorption enhancer with the rectal methadone, so that may be different from just using methadone that is meant to be taken orally.
 
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Well I did it, I plugged a 1/3 of my dose, because of the BA being slightly lower. But I'd say that yes it definitely hit me fast and maybe harder.

I'm not dealing with 10mg/1ml otherwise I'd of plugged the lot.

I'm using regular 1mg/1ml and it would have taken sometime to get it all up if I'd of plugged all of my 'done but I didn't wanna risk losing any after reading another Bluelighter's post about how he plugged 140mg liquid methadone and ended up losing I think he said more than half because it came out! 8o

I don't think he laid down/used gravities help to keep it in. :\

I think never time I may do the lot, but I'll need a larger syringe, which I don't fancy!
 
Plugging Large Liquid Doses

I'm doing this thread because of this thread 'Plugging Methadone Sugar-Free Liquid:- http://www.bluelight.ru/vb/threads/669430-Plugging-Methadone-Sugar-Free-Liquid

I used 5ml syringes to get the dose's in, but if I was to use a larger syringe (I'm not sure if there is such a thing) I imagine it'd hurt like hell and potentially do some damage.

Does anyone know whatever I could use for plugging up to 100ml quickly and easily?

Thank you in advance!
 
I think never time I may do the lot, but I'll need a larger syringe, which I don't fancy!

In the interest of reducing harm to your ass, you can get a bulb syringe. Example pic:

NSFW:
636px-Rectal_bulb_syringe.jpg
 
I'm doing this thread because of this thread 'Plugging Methadone Sugar-Free Liquid:- http://www.bluelight.ru/vb/threads/669430-Plugging-Methadone-Sugar-Free-Liquid

I used 5ml syringes to get the dose's in, but if I was to use a larger syringe (I'm not sure if there is such a thing) I imagine it'd hurt like hell and potentially do some damage.

Does anyone know whatever I could use for plugging up to 100ml quickly and easily?


Thank you in advance!

They make 100mL syringes.... But I would REALLY advise you take at least half of your dose orally... That would make it a helluva lot easier to work with, because you could use a 50mL syringe, or what I would do... just because I already have plenty of my favorite brand of 10mL rigs, so I'd use 5 x 10mL, and with the syringes I have which can actually draw back and hold I'd guesstimate 12-14mL, I could probably fit 50ml in 3.5-4 x 10mL which is a decent amount of volume, wayyyyyy moreso than 100mL.
 
They have larger syringes for administering doses to farm animals. Some farm supply stores have them
 
^thats my thought too, especially as you want to keep the drug in the lower area of the rectum, as the veins in the upper rectum are less efficient as the drug enters I believe the hepatic portal vein subjecting it to first pass metabolism, which in the case of methadone I imagine would not be a bad thing considering oral methadone goes through first pass too, yet still has an incredibly high bioavailability (for many other drugs like buprenorphine and morphine, first past metabolism greatly reduces the concentration levels of the substance during the process). However I would still think 100mL would be risky even with methadones high absorption rate despite the first pass metabolism, as there is likely to also be more fecal matter in the upper rectum to deviously steal and absorb your methadone from you!

My advice might be to just push down on the plunger very slowly, and to not insert the oral/anal syringe more than 4cm (info courtesy of tricomb, check out his posts in the plugging megathread.
 
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could one not slowly evaporate the solution leaving behind methadone/juice crystals etc and the re-dissolve it ine say 3-5 ml's of water to make it more suitable to plug?

My roomate and I once had 10 mg/ml solution which was just methadone and water....we evaporated the water and used it IV.(don;t do this with done mixed with juice though)
 
Let me clarify that I was just stating that they make higher volume syringes.

Although I myself have never used a syringe larger than 10mL, I am aware of the existence of 20mL, 30mL, 50mL, 100mL... etc.

I would advise against using syringes intended for non-human use, be sure you're buying legit sterile packaged fully sealed.... JUST IN CASE. I would rather spend more money for a better made syringe than get a huge amount of shitty syringes for cheap. This is just my experience/thoughts.

I know that rectal methadone comes on extremely rapidly and (with the tablets...) you don't need a huge volume of water, but you have the 1mg/1mL liquid methadone.

I would seriously reconsider whether it's worth it to try and evaporate it down to a more concentrated solution, but I think you should NOT try to evaporate it down for a variety of reasons. 1) You're going to be concentrating the inactive ingredients too, 2) you'd probably ruin some of the active ingredient (methadone), and 3) you have better options, even a good 10mL syringe would probably make a big difference and you wouldn't feel the need to try and evap down your methadone.
 
^How would you ruin it? I'm not suggesting baking it in the oven or anything....maybe justy in an above room temp room....and in my experience most pharmacies clinics don't ever spend thew money for real fruit juice to mix their methadone...It's usually a cheap bulk powder crystal mix like ( mine comes in tang) So I dont think the solutuion would go bad if it had to sit for a day or 3 to completely evaporate...And even if it was no longer suitable for oral ingestion,it should still be good rectally no?

I get a weeks worth of Take homes at a time....I think I may try this and see what happens....I'm just worried about being left with a sticky taffy like substance left rather then crystals from the sugars and stuff in the juice mix.
 
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