• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums
  • BDD Moderators: Keif’ Richards | negrogesic

Please someone read I need help....

Mia.Carlson66

Bluelighter
Joined
Dec 7, 2014
Messages
78
Okay, I plug percocets daily. I get a script of 90 10-325. I take normally 9 a day. If I go over 9 I cwe the rest. I never go over 3000mg of apap a day. I normally plug 2-3 at a time and give 3-4 hour intervals between doses. I do this for 7-10 days for the last 6 months. I am getting worried though. Can this amount kill someone? When I run out I buy from a friend usually do 4 a day when I run out. I know you guys are not doctors, just want some opinions. I do get nauseated after I take my doses sometimes but its motion sickness and subsides after a couple hours, I think this is due to the opiates. I may feel some discomfort in my right upper abdomen sometimes but I'm not positive because of how worried I am lately about this. My mind may be tricking me. I know the recommended doses of apap and symptoms of overdose. I do plan on quoting, I only have 3 left after that I'm done!!!!!! If I show any signs of overdose I am going to er as well but I need some opinions on how bad what I've done actually is. Please
 
So you've been taking the same doses for months and you're asking if the doses you've been taking without a problem will produce an overdose? No.

If you drastically exceed your normal doses or combine the oxycodone/APAP (percocet) with other sedatives or opioids, you could be in trouble but if you're only taking the oxycodone in doses you have been steadily taking for some time, I don't see how you could suddenly overdose.

If you really plan on quitting, be prepared for what that entails. Read up on what to except and have a plan to deal with it when it inevitably comes. If you'd like some advice on such, let me know.
 
I guess I worded that wrong. I have been taking these doses for 10 days about every month for 6 months. I am worried of liver damage I could have possibly done by taking 3g of apap rectally for 10 days straight. I guess it wouldn't be an overdose but I'm worried of liver failure due to long term apap use. That's better wording
 
I've gone through withdrawals before it was miserable and not looking forward to it. I unfortunately went back to opiates after being clean a month. Worst mistake ever. Thank you though.I hope I am okay and just get my life back
 
It's rather unlikely that 3g/day of APAP will produce appreciable liver damage. If you're concerned, S-adenosyl Methionine (sold as SAM-e in grocery stores and supplement shops) has a hepatoprotective effect. You can also ask your doctor to run liver function tests to make sure the APAP isn't causing any problems. Just tell the physician that you're concerned about the APAP in the percocet (and/or say you've taken tylenol without thinking and are worried) and want to make sure you're liver is in tip top shape.

ETA: Alcohol consumption is also very important. If you're drinking at all on top of using those kinds of doses of APAP, you're drastically compounding potential liver damage.
 
No I don't drink, I use to but quit like 3 years ago. Now its very rare like 2 times a year. Lol
 
SAM-e is relatively expensive but also quite safe. I've known very informed people who took rather massive doses when they consumed APAP and were concerned about their liver. It can really have a profound protective effect (much more so than milk thistle which many recommend).

Liver function tests such as AST and ALT are inexpensive, quick and common so requesting such is pretty straight-forward and if presented properly, won't raise suspicions.
 
I was taking milk thistle awhile ago. I haven't taken it in awhile though. I appreciate the info and I feel better now that someone told me its unlikely to cause serious damage at whatvi have been taking. I get really paranoid and when I get like that I can't think about anything and sometimes I convince myself I really am sick. I'm a hypochondriac. I should just stay away from drugs all together lol.
 
It cant necessarily kill you, unless you pop 9 at once, also.depending on dosage... nausia is a side effect, yu should try n eat 30 minutes before taking them, keep in mind ,opiates do affect your liver, that could cause serious health problems in future,,, I have been injecting meth for 5 years, I now have hep c, it will cut my life short, die to fact its attacking my liver... my advice, get support , rehab etc,, its no good. And not worth risking your life, but if.you decide to continue, please take precautions, limit your self, and take care...god bless
 
I'd def get the lover function test done. Pain in upper right abdomen COULD be your lover (or not).
 
Oops... Make that liver. Dam predictive text...Tho a lover function test might also serve a purpose in certain situations! :-)
 
I can't help but feel like plugging 3g of APAP would be much worse than eating it, though I've never spent much time reading into the mechanism of APAP hepatotoxicity so I'm not sure if bypassing a large chunk of first pass metabolism is beneficial or dangerous. Anyone?

Edit: Found this. You should really try make a habit out of CWE'ing if you're concerned about your liver. Seems like this ROA has widely variable peak plasma levels person to person. Not a gamble I'd be willing to take if so easily avoidable.

Rectal administration of acetaminophen may also lead to toxicity, because this route of administration produces peak drug levels that may vary by as much as ninefold and often does not achieve therapeutic levels after the recommended doses are administered.7–9
 
Last edited:
Intrarectal bioavailability of paracetamol (APAP here in the UK) is only half that of oral bioavailability, so this is probably a less harmful method. Id still go down the CWE route personally though.


"The oral administration shows an absolute bioavailability of 60-70% independent of the pharmaceutical form and gastric contents. The rectal administration shows a lower absolute bioavailability (of about 30-40 %) substantially independent of dose in the range under consideration"
 
Yeah, I have read up on rectal administration a lot! I mean a lot! Lol. I have read that the absorption of acetaminophen is slow and incomplete. So I figure that means not all of it is absorbed by the rectum. Even if it is though, I never go over 3g a day. I only do this for 7-10 out of the month. After that I do on average 4 a day for the rest of the month. I have recently switched to dilaudid though, because I don't like plugging the apap all the time. I am trying to taper down also.
 
Why not just CWE your whole batch and get dosage down to a science? Forget the Tylenol, it is not worth it in terms of your liver.
 
I agree with Cane, your dosage would be safe under the current guidelines but the upper abdominal pain is a symptom of liver damage. I would go to your primary care physician and be honest with them (I've told mine about my opioid usage, they keep that confidential) and request ALT/AST testing.
 
If you plan on taking quitting seriously, and you truely dont need the percs, do so now. I think your at what most of us would consider a fairly low threshold as far as opiate tolerance is concerned. Back when they sold morphine, heroin etc at druggist stores after the civil war and into the early 1900's........doctors found that a person more or less could increase there ceiling for WD to rediculous levels, some reported at 200 times the lethal dose for the opiate naive person. And considering that was a time where folks order a "hypodermic needle injection kit" and used smaller amounts of the drugs in baby meds, Im pretty sure you very far away from burying yourself in the rabbit hole. Get your next script, and taper down every three to four days or so until you get down to a half pill a few times and then quit for good. I have to use oxys norcos valium dilaudids etc every day for chronic pain and the appeal of the drug has wore off, and it is quite the bitch when you absolutely need it. It gets to a point where no doctor Ive ever come across that you expect to keep his liscense to practice medicine will up your dose as frequently as the drug demands you use more. Lots of doctors prescribing them have never used opiates and are far from trigger happy so to speak so regardless you end up calling your shady friend(S) to get those percs..........he dosent have any...... youve scored xanax and herb from him a few times. You tell him to score you whatever will cure your dope sick, and eventually youll try H. Ive never used the needle, that was my line.......but smoking it or snorting it is bad enough. I used to laugh at H, tell people they were disqusting etc. The bottom line is once you get to that point, where youre very existance depends on the drug.......your will power is broken.......nobody escapes it. Alright. Ill end my preaching there...............one more thing actually. If you find you have an extremely addictive personality and you have difficulty getting away from the drugs...........get on suboxone. Opiates more or less dont work while your on it, and its 100x better than being dope sick. My personal opinion dont got the sub route unless you need the crutch to stop. However do your research and realize its actually a lot stronger than what your taking, aside the fact there isnt many desirable effects aside from curing dope sickness. Good luck. Quit while your ahead youll need these drugs later for pain and be happy you saved the best for last. Oh yea, and smoke weed every day. That always helps the body mind and soul.
 
Top