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  • BDD Moderators: Keif’ Richards

Please help me convert Oxycodone 5mg dose to an Oxymorphone IR equivilant dose

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Parabunter

Greenlighter
Joined
Aug 13, 2013
Messages
38
Hello,
My friend is requesting assistance finding a dose equivalent to Oxycodone 5mg when switching to Oxymoprhone IR insufflated .

(removing extra frivolous details)
 
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I would be extremely grateful if someone could answer this, please. :D Perhaps I wrote too much. Here it is, simplified: 5mg Oxycodone IR = Xmg Opana IR ...solve for X ?
 
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id just snort half of the Opana (or 5mg) because unless you IV them the amount of actual oxymorphone entering your system effectively is somewhat limited.
 
Keith_Bandit... (Or anyone who might answer)how much would that be equal to then, in oxycodone terms? Is what you are saying is that it's too small of an amount to make it in there? If so then let's pretend that that was not an issue. How much would be equal to 5mg then ?

( Kittycat5, That amount is not correct. I think that's the oral#) . Thank you.

*BTW she has still not begun the Opana ,and the oxycodone is running low, so please take a moment to answer.
 
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Ok you are, aking this a little harder to understand than it has to be. First of all please just use "I" rather than your friend. Secondly..what you are asking is just how much oxymorphone would you take to replace the oxycodone 5mg that you normally take? Or, as you stated in a different place in your post, you want to take them both at the same time?

Oxymorphone is twice as strong as oxycodone when taken orally. So 5mg of oxycodone is equivalent to 2.5mg of oxymorphone.

http://www.bluelight.org/vb/threads/286899-The-Ultimate-Opiate-Conversion-Chart-Ratio-Thread-(-Links-amp-Personal-Experiences)

This link also shows half lives of the drugs...all it takes is a little research...info already here on BL...

http://en.m.wikipedia.org/wiki/Equianalgesic


http:// http://www.globalrph.com/narcotic.htm
 
Oh no... I guess I said too much. Too much info seems to not be a good thing.

I thought I was pretty clear though, in the title and in the original question.

I want to know how much opana IR it would take( when the opana is insufflated) to equal 5mg of oxycodone .... that's it.
 
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The equivalence chart is only going to tell you what each drug compares to. It doesn't specify and I believe the ROA is assumed to be oral. So if I was in your situation, I would start low like 2 mg if you really want to snort it. See how it compares to oxycodone 5 mg. Opana hits you harder than oxy in my opinion. Remember you can always dose more if you find that amount not satisfactory.
 
T.Calderone , I really appreciate the response.

I just read from another source that 2mg would be closer to 16mg of oxycodone. Is that correct?
 
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^That's probably closer insufflated, better to be safe and start out small even 1 mg. Let us know how it works out for you!
 
Agreed...i think the most important thing is regardless is to just start small and go slow. It is a sgronger drug..you can always take more but cant undo it once you have taken it...just be careful and good luck!
 
Missmeyet? and T.Calderone , thank you.

Apparently it is working well for her. She told me to tell you all thanks ;) . She says that the Opana is obviously much stronger, and with the longer life it took a while to realize that. She also urges others to also be very careful with it... and realize that the half life is an imporatant part of the equation. (edit: she was taking the oxyC at the same time during this).

Thanks for your help.
 
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...Update.. (I erased my prev. comment to say..... the jury is still out on what a working conversion is, here. It actually is different than oxycodone, and not just 'convertible' it seems).
 
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5mg oxycodone is equivalent to 2.5mg oxymorphone on a clinical analgesic scale but in terms of recreational value i'd say you need more like 1-2mg oxymorphone.
 
Crashing, I'm confused by that last statement... are you saying that it takes less for recreation?

edit: (to comment below) yeah, she said that too.... she said it feels a bit more "mood lifting" but does not seem to stick to the pain as well, which is the real goal for her.
 
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I'm saying that clinical equivalencies measure the analgesic efficacy of the drugs ( the intended use ). However the feeling of being high is regulated by a different mechanism, for example i think oxymorphone has a higher ratio affinity at the mu receptor site (responsible for euphoria) opposed to the delta or kappa (analgesia and sedation) receptor sites than oxycodone.

So the actual conversion for analgesia versus a recreational euphoria is going to be slightly differrent, as the two drugs have different binding affinity ratios.

All this, and we haven't accounted for bioavailability which is extremely critical.

IMO there's a lot more involved than an opiate chart from google
 
Oxymorphone's intranasal bioavailability is 40%. Its oral bioavailability is only 10%. So that means a dose of 5mgs orally, you are actually getting .5mgs. At the same dose snorting you will get 2mgs. If you snort a dose of 1.5mgs, you will actually get .6mgs of it so that's closest to what your 5mgs would do.
 
deidara.....THank You! wow, that 's pretty cool. (* edit: I have a question about your math, that i'll add at the end).

What I came back here to write, was that She said that 1/8th of a 10mg OxyM seems to feel about the same as 5mg of OxyC , when the former is insufflated. That's 1.25 mg ! So, that's pretty close !

If that's true then it turns out that it's only about 4x's stronger when insufflated than the OxyC . That's a BIG difference from 8-12X's stronger , as I first read here, in old threads.

Their math was ....if PO is 2X's stronger, and intranasal bioavailability is 4X's what it is for PO, then it must follow that --> 2 x 4 = 8 . .... So, it's 8x's stronger. That is apparently not the case. ... (Although please don't take my, or her word for it ! ... it does have a longer half life, and just a different type of results in general...) she said it's not a perfect conversion at 4x's either. Sometimes it feels stronger, and much of the time much less strong than the OxyC. She concluded that there is some strange variability in it.


deidara,... about that last sentence...
...a dose of 1.5mgs, you will actually get .6mgs of it so that's closest to what your 5mgs would do.
Click to expand...

I don't quite follow how the .6mgs is equal to 5mg of OxyC ? Is it just a math error , or am I not seeing ?
 
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