RushHour09
Greenlighter
- Joined
- Dec 15, 2008
- Messages
- 11
Piracetam is a very novel drug, and it seems that its MOA has long eluded pharmacological assay, but the general theme is that it activates no major receptors and is non-toxic and very unreactive, but facilities the action of ion carriers, neuronal membrane permeability, cross-hemispheric communication in brain, and upregulates certain adenylate cyclase and mitochondrial activity, as well as increasing O2 efficiency and oxygen metabolic rates. Increased monoamine turnover may also be involved.
It also enhances the subjective feeling of certain psychostimulant and hallucinogenic drugs. I am a big fan of it just by itself due to its effect on memory and mood, and have taken in combination with a few other things.
MDMA + Piracetam: This is the most frequently encountered combination. For me by a magnitude of about 1/4 to 1/3 it increases the initial come up intensity and plateue effect, when compared to MD on its own. May also quicken the comeup time. Usually When I feel an alert the MD gradually takes hold and rises to full intensity within 5-10 minutes, and then follows a wavy pattern of coming down a little, and then back up alot more and so on.
With piracetam this is not so, the intial comeup is boiled down to a 2-3 minute period of first alert, then rapid increase of intensity which feels like my head blowing up like a balloon, and then peak/ platuea. The wavery effect of MD in intensity of effects is also made consistent, I took MD with piracetam 2 times, then once without, and then another 3 times with.
For comparison when I took it without I didnt even feel like I came up properly, was more gradual, and I just felt chilled and buzzed, and this was a standard dose of good MDMA. also, I dont take md that frequently at all. When I took with the pira, the first time, there was no comeup, it was "Oh shit wtf I feel extremely paranoid all of a sud.." bam, rushing full force.
Theres no dissapointment at the end of main effect either, felt more intense with half a gram of md (2nd time I took) with pira than with just gram by itself. and, 1st experience with, toward the end, it was 6 in the morning, I was sat thinking that I could hack another day, attempting to smoke cannabis to bring me down but which only brought me back up, and with my friends, who by this point was all very lethargic and coming down off the same dose, even my friend who had never eaten MD before, and I was sat still very pinging (rushing), I think I got on there nerve. I notice no wavering of the effects at all, it feels like a 4 hour long peak. your head is much clearer and focusable, seeing as MD tends to be abit foggy sometimes. Also when taking fluoxetine 4-hours post E with this, comedown is abolished.
Psilocybe Cubensis + Piracetam: I dont usually combine psychs with pira, but when thinking about previous experiences, and after doing with and without, for me there is much difference.
For me, ive noticed a wide contrast
consumed 12 grams of atlantis truffles with 3 g+ of pira ingested beforehand, note I hadn't tried truffles before this.
The hallucinations where very sharp, bubbly warpy, waxy, not hazy at all. almost a clear phen-like trip. still the giggles and head buzz/ high, but markedly more controllable thought patterns and clear head. Seeing fire works and even lasers with eyes shut, usually I just get leaves and indian style patterns, followed by subtle wavering and hazy not-sharp movement. The movement was very sharp with the pira, not-so discernable from reality, my radiator consisted of wax melting onto the floor, bob marley kept raising his brow at me from a picture frame. Nitrous in my garden around a fire was the one. Brought on down the sides of my visual field a melay of coiling sinister creatures looking at me, very sharp and clear.
To compare, I doubled the dose of truffles a month later without the piracetam, and it was about 25%-35% less visual, more mental aspects. No lasers, no fireworks, just leaves and patters, hazy wavering of trees and my environment, outdoors, every car had a yellow band wrapped around it like a cop car, light was distorted, but it wasnt nearly as sharp, the latter half consisted of marked ego loss which was extremely transformative aand insightful into the nature of the cosmos and the mechanism behind the fusion of the elements in the stars which we are composed of. Most of the 'choosing aspects of your own personality' effect, and reading minds, but with a markedly less visual component than with half the dose a month prior. summins goin on I think.
Alcohol & Piracetam:
I dont know about this one, it tends to make u more giggle/ drunk/ euphoric but also more clear headed at the same time. piracetam allows more bloodflow to the brain I think.
Ketamine and Piracetam: Much preffered
The pharmacology sais basicly that they have opposing modes of action in the brain, but pira's only an NMDA receptor positive allosteric modulator, aswell as acting on AMPA. The effect is a much clearer head, more centralised feeling, your thoughts arent as wacked out and dispersed on ket, and it doesnt feel like your brain has been hit with a hammer. alot more focused (Ket does dopamine aswell) awake feeling, similar to how I think coke would feel, with still with all the peripheral dissociative trippiness and effects, it actually feels great, when I do this there no negatives with ket, no hangover, not so much drunkeness and no nasty aenesthetic feeling, no tiredness or lethargy after. Like being in the matrix.
LSD, MDMA, Piracetam:
I did too much acid with this one, 2 tabs, after long abstinence, I took first before md. It seemed alot more trippy and sharper than usual, and it came on in ten minutes loll. In future I will start with a much lower dose of potent psychs seeming as ive read intense interactions between such drugs. Despite being in a land where everything was flaming blue, and contained within large bubbles, it was disturbing, people turned into zombies (I was at a warehouse party) and I couldnt figure out who or what I was except that I was composed of something organic, it wasnt too bad but it comepletely over rode the MD. Having tried a half tab of the same acid a few weeks later without piracetam, the hallucinations again seemed alot more sharp with the pira, while on it the air around me seemed to warp and ripple very noticable, while having only low-medium congnitive effects on the half tab with minimal OEVS, mostly a clearing of the mind and senses like a sunny day, and a fair amount of CEV's, and of course many giggles.
MDMA + MDA + Psilocybe Atlantis + 2C-BNbome + Piracetam + Nitrous
Jungle Chemists Delight :')
Funnily enough, it felt like the MDA dominated it, probly because it more amphetamine than MDMA, but yeah. The tryptamine was leading the show though, with the rush powering me along, the hallucinogens conduct the ochestra, taking you to new levels, Nitrous was mental, rainbow coloured hyperspace, I was still tripping 2 days after with no comedown present. I also smoked salvia on the comedown, which for the first time felt very deep, heavy, euphoric, and shamanic. usually I regret taking salvia, but this time it was very pleasant, and grounded my spirit after the phenethylamine comradery. Maybe pira had part to play.
It also enhances the subjective feeling of certain psychostimulant and hallucinogenic drugs. I am a big fan of it just by itself due to its effect on memory and mood, and have taken in combination with a few other things.
MDMA + Piracetam: This is the most frequently encountered combination. For me by a magnitude of about 1/4 to 1/3 it increases the initial come up intensity and plateue effect, when compared to MD on its own. May also quicken the comeup time. Usually When I feel an alert the MD gradually takes hold and rises to full intensity within 5-10 minutes, and then follows a wavy pattern of coming down a little, and then back up alot more and so on.
With piracetam this is not so, the intial comeup is boiled down to a 2-3 minute period of first alert, then rapid increase of intensity which feels like my head blowing up like a balloon, and then peak/ platuea. The wavery effect of MD in intensity of effects is also made consistent, I took MD with piracetam 2 times, then once without, and then another 3 times with.
For comparison when I took it without I didnt even feel like I came up properly, was more gradual, and I just felt chilled and buzzed, and this was a standard dose of good MDMA. also, I dont take md that frequently at all. When I took with the pira, the first time, there was no comeup, it was "Oh shit wtf I feel extremely paranoid all of a sud.." bam, rushing full force.
Theres no dissapointment at the end of main effect either, felt more intense with half a gram of md (2nd time I took) with pira than with just gram by itself. and, 1st experience with, toward the end, it was 6 in the morning, I was sat thinking that I could hack another day, attempting to smoke cannabis to bring me down but which only brought me back up, and with my friends, who by this point was all very lethargic and coming down off the same dose, even my friend who had never eaten MD before, and I was sat still very pinging (rushing), I think I got on there nerve. I notice no wavering of the effects at all, it feels like a 4 hour long peak. your head is much clearer and focusable, seeing as MD tends to be abit foggy sometimes. Also when taking fluoxetine 4-hours post E with this, comedown is abolished.
Psilocybe Cubensis + Piracetam: I dont usually combine psychs with pira, but when thinking about previous experiences, and after doing with and without, for me there is much difference.
For me, ive noticed a wide contrast
consumed 12 grams of atlantis truffles with 3 g+ of pira ingested beforehand, note I hadn't tried truffles before this.
The hallucinations where very sharp, bubbly warpy, waxy, not hazy at all. almost a clear phen-like trip. still the giggles and head buzz/ high, but markedly more controllable thought patterns and clear head. Seeing fire works and even lasers with eyes shut, usually I just get leaves and indian style patterns, followed by subtle wavering and hazy not-sharp movement. The movement was very sharp with the pira, not-so discernable from reality, my radiator consisted of wax melting onto the floor, bob marley kept raising his brow at me from a picture frame. Nitrous in my garden around a fire was the one. Brought on down the sides of my visual field a melay of coiling sinister creatures looking at me, very sharp and clear.
To compare, I doubled the dose of truffles a month later without the piracetam, and it was about 25%-35% less visual, more mental aspects. No lasers, no fireworks, just leaves and patters, hazy wavering of trees and my environment, outdoors, every car had a yellow band wrapped around it like a cop car, light was distorted, but it wasnt nearly as sharp, the latter half consisted of marked ego loss which was extremely transformative aand insightful into the nature of the cosmos and the mechanism behind the fusion of the elements in the stars which we are composed of. Most of the 'choosing aspects of your own personality' effect, and reading minds, but with a markedly less visual component than with half the dose a month prior. summins goin on I think.
Alcohol & Piracetam:
I dont know about this one, it tends to make u more giggle/ drunk/ euphoric but also more clear headed at the same time. piracetam allows more bloodflow to the brain I think.
Ketamine and Piracetam: Much preffered
The pharmacology sais basicly that they have opposing modes of action in the brain, but pira's only an NMDA receptor positive allosteric modulator, aswell as acting on AMPA. The effect is a much clearer head, more centralised feeling, your thoughts arent as wacked out and dispersed on ket, and it doesnt feel like your brain has been hit with a hammer. alot more focused (Ket does dopamine aswell) awake feeling, similar to how I think coke would feel, with still with all the peripheral dissociative trippiness and effects, it actually feels great, when I do this there no negatives with ket, no hangover, not so much drunkeness and no nasty aenesthetic feeling, no tiredness or lethargy after. Like being in the matrix.
LSD, MDMA, Piracetam:
I did too much acid with this one, 2 tabs, after long abstinence, I took first before md. It seemed alot more trippy and sharper than usual, and it came on in ten minutes loll. In future I will start with a much lower dose of potent psychs seeming as ive read intense interactions between such drugs. Despite being in a land where everything was flaming blue, and contained within large bubbles, it was disturbing, people turned into zombies (I was at a warehouse party) and I couldnt figure out who or what I was except that I was composed of something organic, it wasnt too bad but it comepletely over rode the MD. Having tried a half tab of the same acid a few weeks later without piracetam, the hallucinations again seemed alot more sharp with the pira, while on it the air around me seemed to warp and ripple very noticable, while having only low-medium congnitive effects on the half tab with minimal OEVS, mostly a clearing of the mind and senses like a sunny day, and a fair amount of CEV's, and of course many giggles.
MDMA + MDA + Psilocybe Atlantis + 2C-BNbome + Piracetam + Nitrous
Jungle Chemists Delight :')
Funnily enough, it felt like the MDA dominated it, probly because it more amphetamine than MDMA, but yeah. The tryptamine was leading the show though, with the rush powering me along, the hallucinogens conduct the ochestra, taking you to new levels, Nitrous was mental, rainbow coloured hyperspace, I was still tripping 2 days after with no comedown present. I also smoked salvia on the comedown, which for the first time felt very deep, heavy, euphoric, and shamanic. usually I regret taking salvia, but this time it was very pleasant, and grounded my spirit after the phenethylamine comradery. Maybe pira had part to play.
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