Phenylpiperazine HCL [not BZP!]

[BLreturn11]

http://www.erowid.org/experiences/exp.php?ID=22420

^This erowid report suggests the person in question ingested Phenylpiperazine HCL (by mistake thinking it was BZP) and got what appeared to be toxic symptoms.

Clearly not a good idea! & in no way recreational. The report itself got me wondering though, anyone guess (just for novelty) the pharmacology that might have been in play? Predictions on activity? Maybe a more toxic panicogen similar to mCPP?

Looks scarily close to MPTP as well.

 

[basement_shaman]

Phenylpiperazine would mean that there is one carbon less between the aromatic ring and the nitrogen. This is analogous to phenethylamines that are toxic in the phenmethylamine versions or as a better example gramine which is toxic and is basically DMT with one carbon less between the rings and the nitrogen.

 

[acetylcholine]

Assuming that what this guy took was actually phenylpiperazine and not mCPP or some other substituted ppz. His experience sounds very similar to what one would expect from a potent, though not selective, 5-HT2C agonist- like mCPP. In other words a nasty time.

Some scientists did try plain "PP" on animals, but the study is old and the abstract inconclusive. Here's the cite:

Central serotoninmimetic action of phenylpiperazines.

Maj J, Lewandowska A.

Edit: also, the similarity to MPTP and MPP+ is superficial, in my opinion.