pharmacology of chamomile

[thisusername]

Does anyone have any information on the neurological pharmacology of chamomile? Ive looked everywhere but cant find much.

 

[Hammilton]

My guess would be Apigenin, a flavone, as 6-methylapigenin is a known anxiolytic.

Résumé / Abstract
We have recently reported the presence of the anxiolytic flavone 6-methylapigenin (MA) and of the sedative and sleep-enhancing flavanone glycoside 2S ( - ) hesperidin (HN) in Valeriana officinalis and Valeriana wallichii. MA, in turn, was able to potentiate the sleep-inducing properties of HN. The present paper reports the identification in V officinalis of the flavone glycoside linarin (LN) and the discovery that it has, like HN, sedative and sleep-enhancing properties that are potentiated by simultaneous administration of valerenic acid (VA). These effects should be taken into account when considering the pharmacological actions of valeriana extracts.
Revue / Journal Title
Pharmacology, biochemistry and behavior ISSN 0091-3057 CODEN PBBHAU
Source / Source
2004, vol. 77, no2, pp. 399-404 [6 page(s) (article)] (20 ref.)

 

[Limpet_Chicken]

Also which species, there are several plants called chamomile, not all in the same genus, E.g roman chamomile, lawn chamomile etc.

Lovely smelling oil though mmmmm, few drops of that and lavender in rthe bath, with maybe a bit of jasmine, and me be offskis to a nice warm bed with a bong and some munchies not long after

 

[Tsukasa]

I've wondered this myself. So what receptors does it affect if any?

 

[thisusername]

bump

 

[wreckhead]

I think I heard operates through GABA-A agonism. Most other herbal sedatives eventually are shown to work this way, making them probably as addictive as benzos and thus useless in the long run.

 

[Tsukasa]

^ Yea, like valerian or kava kava. allosterically like benzo's.