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Percocet vs. Hydrocodone

coryneil948

Bluelighter
Joined
May 4, 2001
Messages
52
Location
Tampa
I know the Oxycontin posts are closed, but after reading it's FAQ, it appears that Percocet is a somewhat different animal and my question wasn't answered there.
My friend just got her wisdom teeth removed and got the 5mg/325 APAP of Percocet instead of 10mg/325 APAP of Norco (Hydrocodone), which she got last time she needed pain medicine. Taking recreationally, how do these two compare? I have tried 10 - 20 mg. of Hydrocodone with positive effects. Does a similar dosage of Percocet give the same or stronger effects?
 
Percocet is just Oxycodone with APAP. The only difference between percs and oxycontin is the time release in oxycontin and the tylenol in the percs.
As far as oxycodone to hydrocodone, everyone is affected differently, but in nearly all cases oxycodone will give you a better high. Percs could be a better score depending on the number your friend got. I personally would prefer 20 10/325 hydrocodone pills over 20 5/325 percocets.
However, 20mg of oxycodone is definitely going to feel nicer than 20mg of hydrocodone. You should be fine taking this dose though as long as you have some previous opiate experience and know that you enjoy the feeling.
 
The quantity would really be the clencher here.
10mgs of hydrocodone will feel like 7.5mgs of oxycodone.
But like Diffidence said, 20mgs of oxycodone will feel much better than hydrocodone.
Say you're getting 20 of them. Taking 20mgs/4 pills of Percocet at a time, you can get knocked up really nice 5 times.
On the other hand the hydrocodone, while not bad, just won't be as cool.
Then if you have to use sparingly, 20mgs/2 pills of hydro are going to do you better than 10mgs/2 pills of Percocet.
I don't know.. oxycodone is kind of blah until you get to about 15-20mgs.. then you really take off.
 
For some reason I tend to like Hydrocodone better. I don't feel as dopey, but still smashed. And Oxycodone, for some reason, makes me more irratable!
Right now I got these Darvocet(sp?)! They aren't as bad as everbody would believe! Actually they are quite enjoyable. At about 200-300mg of proproxyphene I get off pretty good!
 
I guess I am weird, but when you're talking about taking them orally I find hydrocodone to be slightly better on a mg-for-mg basis .. now if you're snorting or booting it's hands down - oxycodone takes the cake (and I am taking about booting raw hydrocodone powder or hydrocodone extract, not crushing a Vicodin and cooking it down) .. I guess I am weird like that, but if offered a 10mg Vicodin or a 10mg Percocet (to be taken orally, I would opt for the former... now as the dose goes up this all changes - if you're talking about 30mg Vicodin or 30mg Percocet, I opt for the latter... can't explain it, but thats how I am...
 
phreex, as u can tell by my other popsts i like the old point too, how do u cook down vicodin???
 
You don't. You would need to extract it from the acetominophen. Injecting that would be quite stupid.
 
It probably isn't something that will kill you. But thats going to be REALLY hard on the liver. The liver is going to have to now DIRECTLY process all that acetominophen. So basicly its a matter of increasing the toxicity to the liver. There may be other reasons as to why you shouldn't do it. I'm not a doctor, I just know you *do not do it*.
 
It wouldn't kill you, but to disolve all that APAP you would need a good 5cc's of water .. also, because such a TINY percent of the total mass is the active drug you seek. there is a chance you wouldn't get hit as hard as if the APAP wasn't there..
So no, you don't bang these.. now you COULD do a cold-water extract and inject that, but it's really more toruble then it's worth...
Just eat the damn things!
 
Hmm, info update:
First, acetaminophen is only hepatotoxic in large acute doses. There are a couple metabolic pathways, one (actually 2, sulfation/glucuronidation) is saturable, the other (2: via CYP2E1/CYP1A2) produces an intermediate (NAPQI). You take too much, the good pathway is saturated, the bad one starts running, eventually gluthianone stores run out, then the NAPQI turns into toxic metabolites which damage the liver.
Now the minimum toxic dose seems to be 150mg/kg. For me (180lb) this is 12 grams. Less than that at once, no problem. This is much lower if you are consuming alcohol, fasting, using drugs that inhibit P450 enzymes, etc. 4g seems to be the medical acute maximum OK dose in these cases.
Chronic use is typically recommended to be under 4-6 grams/day due to possible slow gluthianone depletion; and the fact that acetaminophen is a nonselective COX inhibitor -- COX-2 has important cytoprotective effects.
So: shooting acetaminophen is no problem; below the threshold toxic dose, no toxicity occurs. Hell, it is absorbed relatively quickly anyways. And doctors obviously have no problem with this: some of the subjects below received 2g IV!
Rawlins MD, Henderson DB, Hijab AR.
Pharmacokinetics of paracetamol (acetaminophen) after intravenous and oral administration.
Eur J Clin Pharmacol 1977 Apr 20;11(4):283-6
 
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