So I was just reading some anecdotal experiences of people taking high-dose loperamide and developing very alarming and possibly permanent symptoms. Years ago, last I was active, I had heard rumors that in theory it could cause some of these symptoms, but I hadn't heard of it actually happening to anyone.
The reason I am concerned is because high-dose loperamide has been my go-to for keeping my sanity during opiate withdrawal. I am currently in a pattern of taking it daily, I have been gradually reducing my usage of opiates and recently I have gotten down to once every 4 days, about to do 5 days. But on all the off days I end up taking loperamide because it makes it all feel better, not great, but bearable. I am actually pretty surprised that even doing opiates only every 4 days still leaves me feeling withdrawal enough to need to medicate it. When I don't take the loperamide on the off days I get horrendous anxiety and depressive thoughts and it is very difficult to sleep from the restlessness. I am starting to wonder if loperamide has a withdrawal of its own.
To make matters more concerning, I have been yoyoing with opiates for years, and loperamide has been my go-to like this for at least 2 years. I have gone through many periods of taking it regularly. And when I say high dose, I mean 50-60mg.
So, I guess I was wondering if anyone has any info on the topic. And I am also thinking I need to find myself some MXE instead so I can low-dose that as needed, because it also combats the withdrawal feelings, at least as well. Give myself a week or so of that and I should be done, and off this damn fucking rollercoaster for good. I'm so close as it is but I think I am deciding not to take loperamide any more because I'm really paranoid that I've been doing significant damage to myself (even though I don't really feel like I have, but I will say that it doesn't feel healthy to be doing, less healthy than just taking opiates even, physically). But I'm afraid of my brain if I don't have something to ease myself. My power to rationalize to myself is extremely strong.