JohnBoy2000
Bluelighter
- Joined
- May 11, 2016
- Messages
- 2,596
I'm just curious as to what the typical protocol for follow up treatment is for patients that have not or only slightly responded to SSRI's, SNRI's or mirtazipine?
I understand sometimes there are adjuncts with anti-psychotics?
Such as olanzapine with fluxotine.
Do they ever add in respiradone or seroquel?
Even without comorbid psychotic features?
The next go to approach would be, I would guess Bupropion/Wellbutrin, being a pure noradrenergic?
I've read anecdotally that Aripripazole is also used as an adjunct?
Wikipedia tells me that that has a fairly nasty side effect profile, and is not fit for use in geriatric patients.
The other anti-psychotic that springs to mind would be, Lamictal.
Often used?
A go-to thing?
Beyond that, I know that there would be a trial with tricyclic AD's.
And failing that, MAOI's - worst case scenario.
Have I nailed the pertinent effects?
Or is the typical protocol a little more diverse?
The clinicaltrials.gov website seems to have conducted the majority of it's trials in terms of non-response to first line SS/NRI's, with Bupropion or Aripripazole.
I understand sometimes there are adjuncts with anti-psychotics?
Such as olanzapine with fluxotine.
Do they ever add in respiradone or seroquel?
Even without comorbid psychotic features?
The next go to approach would be, I would guess Bupropion/Wellbutrin, being a pure noradrenergic?
I've read anecdotally that Aripripazole is also used as an adjunct?
Wikipedia tells me that that has a fairly nasty side effect profile, and is not fit for use in geriatric patients.
The other anti-psychotic that springs to mind would be, Lamictal.
Often used?
A go-to thing?
Beyond that, I know that there would be a trial with tricyclic AD's.
And failing that, MAOI's - worst case scenario.
Have I nailed the pertinent effects?
Or is the typical protocol a little more diverse?
The clinicaltrials.gov website seems to have conducted the majority of it's trials in terms of non-response to first line SS/NRI's, with Bupropion or Aripripazole.