Oxymorphone-3-methoxynaltrexonazine

[Kewlwip]

....or OM-3-MNZ

New here, so bear with me.

How would this substance be looked at under the analogue act?

"Oxymorphone-3-methoxynaltrexonazine, which theoretically could bind only as an agonist, possessed agonist properties in binding studies and was a potent analgesic in vivo."

From:
Oxymorphone-naltrexonazine, a mixed opiate agonist-antagonist.
Galetta S, Hahn EF, Nishimura S, Pasternak GW.
Life Sci. 1987 Aug 10;41(6):783-7.

 

[kken]

not really ADD material. maybe you should post which country you are from if you really want an answer

 

[Kewlwip]

Sorry, the US. Federal Analogue Act.

Thought the ADD crowd would have better knowledge of the FAA.

 

[sekio]

It's illegal because it's derived from a morphine-like structure. It posessing opiate activity doesn't help the case.

 

[Slapdragonx]

Oxymorphone-3-methoxynaltrexonazine:

Naloxazone:

Oxymorphone:

Naltrexone:

I would be scared of it metabolizing into oxymorphazone and naloxazone.

Unless it is the primary amine that allows the covalent bonding with the opiate receptors.

 

[TheAzo]

Am I missing something? Why the hell would anyone make this...?

 

[fryingsquirrel]

Am I missing something? Why the hell would anyone make this...?

I was kinda wondering that myself.

 

[seusemgoose]

Definitely illegal in the US

 

[hamhurricane]

I'm amazed that's active, it fucking gigantic.

 

[Hammilton]

It's not the only big one like that, though. There's Naltrindole, and more interestingly, Norbinaltorphimine. Those are full antagonists though.

 

[Nagelfar]

interesting to have one of those "two duelling heads" of the full morphinan carbon structure as an example of full agonists in addition to those full antagonists I knew of and Hammilton mentioned. For that reason it seems notable enough to me. But just for my own vanity of interest ;-p Though I was thinking of Naloxonazine as comparable to this.