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Opioids Oxycodone Potentiation Experiment

Mako714

Greenlighter
Joined
Sep 7, 2013
Messages
5
will try to keep it short.
Quick Version:I have an 80-160mg per day oxycodone tolerance.
I almost always take orally due to only having access to the 80mg OP's.
So
If i add very small doses (less than .5mg) of Xanax to my dose, could I then effectively lower the amount of oxycodone I need to take to feel good?

As in, by adding the xnx, could I get away with taking half of my normal dose to achieve the same effect Because of the way Benzos seem to potentiate opiates?

The obvious goal here being to stretch out the oxy supply available (financially) to Me.

Is this possible?

Thanks so much for any help.

P.S. Swim is very aware of the risk of respiratory depression from this combo and is more than willing not to push any limits, as well as to always keep dosages low and safe
 
Last edited:
The combo works. Starting with small, alternating doses of one then the other at given intervals may help in finding that sweet spot. As you mentioned, be conscious of synergistic effects. Don't go overboard. Don't dose too rapidly until you know how the combo effects you. Benzos can cause bad decisions.
 
Apologies, my post has been edited accordingly.
So I'm hearing that it might be possible?

Has anyone else tried this before, I know others have tried the combo but has anyone else tried this as a regular practice?

It seems like it may be possible to use half the Oxycodone I've been using if I combine it with Xanax... Essentially doubling the supply I have and saving me money because the bars are a fraction of the price as the OC's
 
This is a very common combo, but don't expect it to stretch your supply or save you a ton of money, at all.

First, you're about to add another addiction to your life. Xanax tolerance develops ridiculously fast, so your plan might work for a week, at most.

Second Xanax, in general, is as - if not more - addictive than oxy. Add the 2 together and now you've just increased your financial burdens.

I also have to just mention it anyways: this combo increases the likelihood of oding by a lot. Remember, adding .5 Xanax won't do shit in a week. Once you start pushing it with the Xanax plus oxy, you'll start to black out more easily and unknowingly take more than you realized.

Basically, don't do what I did... There are a bunch of threads on how to potentiate opiates with none addictive substances.
 
^ AN oxy addiction is no fkin joke, ESPECIALLY if you're not prescribed it. So there's that. You also sound like your tolerance has risen. Maybe consider a break ?

If you wanna potentiate benzos work great, so do barbs, and pure grape fruit also helps too.
 
swim = someone who is me.
Anyways, I've found a single 200mg tagment (cimetidine) about an hour before and 45-60mg dxm a half hour before, along with some piperine occasionaly, a good way to potentiate. Then toss in some benadryl if you want more sedation. I wouldn't advocate the use of xanax, that's just me though since the respritory depression with oxy and cimetidine for me seems to be increased, and I believe cimetidine IIRC potentiates your benzo.

It seems the cimetidine delays you're come up, but when it comes it starts to hit, it hits hard and it lasts forever, with me at least.
 
Yes that would work. Also cimetidine or white grapefruit juice are incredibly helpful to potentiate oxy especially, and opiates in general, if timed right. However be careful with any potentiation, Xanax especially, but cimetidine etc too, as they are addicting and should be used rarely
 
is this like an after-work thing?

cause if you're just looking to relax, i'd do: benadryl like 30 min before, then after do a couple shots of alcohol, oxy, 1 melatonin pill (3mg) - all on an empty stomach
additional 'ingredients' are very cheap, sedating, use less oxy, and you don't have to mess with benzos (higher addiction potential)

i've never used grapefruit juice so i can't speak for that. don't over-do the alcohol

and try not to make it a habit etc, try reading the dark side threads
 
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