Oxycodone ~ Pain Relief : take 3 x 80mg/day vs. 40mg every 4hrs ?

[Scoliosis]

Ok, so this question was proposed to me last year and I never got around to asking it on a a forum with so many other knowledgeable people with real life experiences.

Forget BOUT textbooks and what your doc will tell you.

They told me 80mg would help my pain for 12 hours. then 8hrs.... bullshit. My body will hurt after 6 hours upon taking 80mg Oxycodone. (I have 3 x 10mg /day of the Instant Release Oxy - no acetaminophen or anything else, pure oxy* in between doses as per every 8hours RX'd*)

So, would it be more effective to take 40mg every 4 hours , 6 per day or ......
3 x 80mg Oxy to fight chronic pain ?

Have you tried this ? Thoughts? Suggestions? This could be a good taper down for people trying to take less too?

Have a great weekend y'all , and Happy Eggnog filled Holidays!!!! %)%)

 

[Scoliosis]

cant beleive no one replied. wha the fuck?

 

[amapola]

The half life of oxycodone is about 4 hours.

edit:

40mg every 4 hours
max: (((((40/2)+40)/2)+40)/2+40)/2+40) ... approaching 80
min: (((((40/2)+40)/2)+40)/2+40)/2+40)/2 ... approaching 40

80mg every 8 hours
max: (80/4+80)/4+80 ... ~107
min: (80/4+80)/4 ... ~26

 

[TheLostBoys]

I would definitely cut the 80's in half & do them every 4 hours like you first suggested. Also, you have the 10mg for breakthrough pain, you should be fine. You gotta find out what works for you. What works for someone else may not work for you. Trial & error bro, good luck!

 

[phatass]

if you take 6 times 40mg every 4 hours that would mean you're awake 24 hours a day... however you're only awake for about 12 hours on average lets say, thats 80mg every 4 hours 3 times per dayor take 80mg every 6 hours and then you'll have 80mg before sleeping to not wake up becoz of the pain
(hope this makes sense)

 

[Scoliosis]

THIS REMINDS ME OF A MATH EQUATION OF SORTS?? CAN YOU GIVE IT TO ME LIKE I AM 5 YRS OLD?

The half life of oxycodone is about 4 hours.

edit:

40mg every 4 hours
max: (((((40/2)+40)/2)+40)/2+40)/2+40) ... approaching 80
min: (((((40/2)+40)/2)+40)/2+40)/2+40)/2 ... approaching 40

80mg every 8 hours
max: (80/4+80)/4+80 ... ~107
min: (80/4+80)/4 ... ~26

 

[Scoliosis]

Here is what I was planning:

10am - 40mg
4pm - same
10pm - same.
3am - 40mg.

with the 10mg IR as required.... 3 a day.

if you take 6 times 40mg every 4 hours that would mean you're awake 24 hours a day... however you're only awake for about 12 hours on average lets say, thats 80mg every 4 hours 3 times per dayor take 80mg every 6 hours and then you'll have 80mg before sleeping to not wake up becoz of the pain
(hope this makes sense)

 

[K'd-OUT-in-AZ]

It would be better to take the OxyContin x3 a day because you get a higher initial dose so you'll feel better. Just make sure to chew the OxyContin, or chop it in powder.

 

[Scoliosis]

WAIT a sec, are you saying take my 3 x 80mg as rx'd daily every 8 hours? Except, instead of swallowing them whole to chew or parachute????? crush?????

...would it still hold me through the full time till next dose? .. 8 hrs later??? I meanm if I did crush or so, would the effect still last?*

Are you sure >> ??

I thought it would be better to swallow whole so I got constant pain relief as long as possible and for as much as possible in each 8hr interval*****

ON a personal note, please check ~ pm.

It would be better to take the OxyContin x3 a day because you get a higher initial dose so you'll feel better. Just make sure to chew the OxyContin, or chop it in powder.

 

[amapola]

THIS REMINDS ME OF A MATH EQUATION OF SORTS?? CAN YOU GIVE IT TO ME LIKE I AM 5 YRS OLD?

Yes well not so much equations as series. Anyways to simplify...

The half life of oxycodone is 4h meaning half of it decays 4 hours after you take it.

If you consistently take 80mg every 8 hours...
Maximum:
The maximum amount of drugs in your body will be about an 107mg dose. This will occur shortly after you take the meds and will be the new 80mg you take plus the leftover 20mg from the dose before and another 5 from the dose before that etc. etc.

Minimum:
The minimum amount of drugs in your body will be about a 27mg dose. This will occur right before you take another 80mg and is the sum of all your previous doses.

If you consistently take 40mg every 4 hours...
Maximum:
The maximum amount of drugs in your body will be about an 80mg dose. This will occur shortly after you take the meds and will be the new 40mg you take plus the leftover 20mg from the dose before and another 10mg from the dose before that etc. etc.

Minimum:
The minimum amount of drugs in your body will be about a 40mg dose. This will occur right before you take another 40mg and is the sum of all your previous doses.


To Summarize...
If you take 80 every 8 hours you will get higher highs (with 107mg dose) but lower lows (with only 27mg in your system). Since you say you start feeling pain again after 6hours this means the low is too low for you.

If you take 40 every 4 hours your highs won't be as good (only 80mg) but your lows aren't so bad (maintaining at least 40mg). Which is probably around where you are still getting pain relief, i.e. before 6h mark in 80mg/8h.

Take 80/8 if you want to get high and then feel some pain.
Take 40/4 if you want a solid average dosage.

 

[Scoliosis]

Well done, I have legit scoliosis:

Mild symmetric disc bulging L-3-L4 and L4-L5. Mild to moderate left facet joint osteoarthritis L-3-L4. Thoracolumbar rotoscoliosis. And some more. That;s just a small taste ... small.

Correction: I said 40mg - 6hours , not 4hours. So for overall pain relief you say take 40mg every 4-6 hours?

Yes well not so much equations as series. Anyways to simplify...

The half life of oxycodone is 4h meaning half of it decays 4 hours after you take it.

If you consistently take 80mg every 8 hours...
Maximum:
The maximum amount of drugs in your body will be about an 107mg dose. This will occur shortly after you take the meds and will be the new 80mg you take plus the leftover 20mg from the dose before and another 5 from the dose before that etc. etc.

Minimum:
The minimum amount of drugs in your body will be about a 27mg dose. This will occur right before you take another 80mg and is the sum of all your previous doses.

If you consistently take 40mg every 4 hours...
Maximum:
The maximum amount of drugs in your body will be about an 80mg dose. This will occur shortly after you take the meds and will be the new 40mg you take plus the leftover 20mg from the dose before and another 10mg from the dose before that etc. etc.

Minimum:
The minimum amount of drugs in your body will be about a 40mg dose. This will occur right before you take another 40mg and is the sum of all your previous doses.


To Summarize...
If you take 80 every 8 hours you will get higher highs (with 107mg dose) but lower lows (with only 27mg in your system). Since you say you start feeling pain again after 6hours this means the low is too low for you.

If you take 40 every 4 hours your highs won't be as good (only 80mg) but your lows aren't so bad (maintaining at least 40mg). Which is probably around where you are still getting pain relief, i.e. before 6h mark in 80mg/8h.

Take 80/8 if you want to get high and then feel some pain.
Take 40/4 if you want a solid average dosage.

 

[amapola]

Correction: I said 40mg - 6hours , not 4hours. So for overall pain relief you say take 40mg every 4-6 hours?

Sorry I was just going off of your first post...

So, would it be more effective to take 40mg every 4 hours , 6 per day or ......
3 x 80mg Oxy to fight chronic pain ?

So yeah you can draw your own conclusion on what is best for you from the data.
Either way you are consuming 240mg per day so the more you spread it out the closer you get to a constant dose of 60mg or whatever.

 

[Violenza666]

I'd likely take the 40 6 times a day and take the instant release at strategic moments. I do the same with my opana. I dose what I have the most effective way for me. Do what works for you. I get two opanas a day. But I dose 3 times a day 4 on a bad day. On a good day I only take 1, on a bad day I take two. I snort Opana because it's BA is higher nasally. I get Oxy IR as well. The 30's though. I take those as needed in between. I try to use less though.

What I did was taper down so I could use as needed. Now I dose based on my pain levels not constantly. That way I don't ever have to deal with WD or any of that nonsense.

Have you spoken to your dr about this or is it a lost cause? Other than this hope you are well.

ETA: Do you take a NSAID as well or any Muscle Relaxers? Ibuprofen and Soma could work wonders for you as well. Combined with the oxy it will help a great deal.

 

[Scoliosis]

Looks like I have found the BEST solution all around, and I do appreciate all of your input, everyone's!!

40mg every 6hours .... will taper me down to 2 x 80mg per day ..
(instead of 3)

The 30mg IR - in 10mgs doses ... I will need to take in between. As needed.

but when all this talk and chat is done, my pain is real. This post is not about getting buzzed. I suffer from real discomfort and pain. something many of these young docs cannot learn about in textbooks.

WHY did you get oxymorpone vs oxycodone? and the muscle relax's .. I used to take Flexeril , it was great but knocked me out. My spasms are all but gone on the high oxy doses and only come back when its cold, like - 15 + outside.
No amount of pain meds will help me at - 25+ , no amount.

... Ibuprofen - no help.

I'd likely take the 40 6 times a day and take the instant release at strategic moments. I do the same with my opana. I dose what I have the most effective way for me. Do what works for you. I get two opanas a day. But I dose 3 times a day 4 on a bad day. On a good day I only take 1, on a bad day I take two. I snort Opana because it's BA is higher nasally. I get Oxy IR as well. The 30's though. I take those as needed in between. I try to use less though.

What I did was taper down so I could use as needed. Now I dose based on my pain levels not constantly. That way I don't ever have to deal with WD or any of that nonsense.

Have you spoken to your dr about this or is it a lost cause? Other than this hope you are well.

ETA: Do you take a NSAID as well or any Muscle Relaxers? Ibuprofen and Soma could work wonders for you as well. Combined with the oxy it will help a great deal.

 

[Violenza666]

Looks like I have found the BEST solution all around, and I do appreciate all of your input, everyone's!!

40mg every 6hours .... will taper me down to 2 x 80mg per day ..
(instead of 3)

The 30mg IR - in 10mgs doses ... I will need to take in between. As needed.

but when all this talk and chat is done, my pain is real. This post is not about getting buzzed. I suffer from real discomfort and pain. something many of these young docs cannot learn about in textbooks.

WHY did you get oxymorpone vs oxycodone? and the muscle relax's .. I used to take Flexeril , it was great but knocked me out. My spasms are all but gone on the high oxy doses and only come back when its cold, like - 15 + outside.
No amount of pain meds will help me at - 25+ , no amount.

... Ibuprofen - no help.

I got the Oxymorphone because my dr believes in 2 medications to fight pain. There are 7 receptors in your brain that deal with pain not all medications will fix it all but 2 opiate medications make it more likely for your pain relief to be achieved. In my case Oxycodone and Oxymorphone. Upon research I found that his theory was to be true. Ibuprofen only works for me in combination with all the other medication I take.

Flexeril is junk. Soma is good and it poteniates the opiates and makes them work better.

The cold makes my pain worse as well so I completely understand.

Good luck