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Opioids Oxy and your liver

TJvaper

Greenlighter
Joined
Aug 30, 2011
Messages
40
Location
Ontario, Canada
Oxy and General health

Hi folks! I am hoping there are some bluelighters that have medical knowledge for this one. I want to know if long time oxy users have the same health risk that long time alcohol users do, namely Cirrhosis of the liver.

I have been a user now for about 3 years. My current dose is 100mg every 10 days or so. Does anyone know if Cirrhosis is a serious concern at this level?

Much thanks!
 
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Well I don't know the technical answer to your question but I'm sure you can find it online if you really want to. I will tell you from years of pain management that usually folks go on medicine like Percocet but once their dosage creeps up they will typically get switched to Oxy (one kind or another) without the APAP because that's the piece that's harsh on the body and needs to be limited to prevent damage. So, I can only deduce that the Oxy is not the problem.
 
It's the acetaminophen that fucks up your liver. I asked my pain management doctor and he told me oxycodone alone is pretty safe. It's when people use Percocet or hydrocodone with apap that you must be careful how many you take and for how long.
 
Yeah I must say that once switching to roxicodone, I have never looked back except in one regard: Although for whatever reason, I believe that PERCOCET is a helluva lot more effective taken rectally than Roxicodone (ANYONE ELSE EXPERIENCE THIS PHENOMENON?!), but I only take my medication orally as directed these days and the only complaint I have with it is of course, it doesn't last long enough.

That's what lead me to plug oxycodone to begin with, when I would plug percocet I could get analgesia for like 4-6 hours and oral oxycodone IR means analgesia for like 2-3.5h at best depending on multiple factors such as other medications ingested, but pretty much nothing can extend the duration of oxycodone longer than about 3 hours for me.... I'm looking into this D-Phenylalanine stuff though which may or may not help me extend the duration of my oxycodone IR.
 
Thanks for the replies all. Very informative as usual. I am not taking oxy via percs, just the straight stuff. Well, as straight as is possible these days with the fillers used in OP type meds, but def no APAP.

I have plugged oxy before tricomb and did not notice any duration difference myself, but everyone reacts slightly different I think in certain ways to identical drugs. We are all unique in more ways than one. Love all your locations, lol!
 
Hey, before letting this thread die off, perhaps I could just dig a bit further, and ask if there are other health concerns that may be related to oxy use, such as stomach cancer, ulcers, etc. I have heard that the filler used in the pill formation (in the US & possibly Canada) contains a carcinogenic compound that is banned in other countries.
 
Hey, before letting this thread die off, perhaps I could just dig a bit further, and ask if there are other health concerns that may be related to oxy use, such as stomach cancer, ulcers, etc. I have heard that the filler used in the pill formation (in the US & possibly Canada) contains a carcinogenic compound that is banned in other countries.

It's BHT..... And yeah. That's one reason I don't take OxyContin (the other being.... I hate the OP formulation). If they brought back the OC's, I'd gladly go back... Until then, I would much rather take roxicodone as it contains no nonsense. No carcinogens. And some of the fewest inactive ingredients I've EVER seen for a pharmaceutical opioid, possibly only rivaled by that of Dilaudid IR.

Has anyone seen the Roxicodone 5mg? They are white, and contain ZERO of the dyes OR additives added to the colored (10, 15, 20, 30mg) tabs. There is also a substantial difference in price, but we can't go into this further than this.

In my subjective opinion and based on all the research I've done (which is EXTENSIVE, I assure you), the 5mg Roxicodones are by and far one of the cleanest pills I've ever come across. Granted, this is GREAT for people like me who don't inject their medication, but I can see why such a small 5mg formulation wouldn't work for people like... well, I know someone who regularly does shots of 500mg+ oxycodone, and that would require what, 1000 x 5mg roxis?

But if your an oral doser, and are really worried about the BHT or the plastic polymer bullshit in OxyContin and the similar INTAC or w/e, I cant even keep up with them all these days, whatever Opana ER's time-release/abuse-deterrent recipe is. But I want nothing to do with it and since arguably the most important vote that counts is the vote you cast with your dollar, I refuse to finance companies that practice beyond questionable business ethics, *cough cough* most modern non-morphine ER medications *cough cough*

edit: I just consulted Sekio, and he says that he's not concerned at all about the BHT in USA OxyContin (then again... he doesn't have to take the BHT-formulation, he has access to OxyNeo if he were so inclined....), he even went as far as to say that it was an antioxidant and raises the valid point that in many countries, particularly the United States, you can find BHT in just about anything as a preservative/additive. It's in everything from food, to food packaging, even jet fuel (not like this is very reassuring!!!! LOL).

So yeah, I don't think it's cool that the USA Purdue OxyContin formulation elected to save pennies on the dollar by utilizing such a questionable ingredient, one that's so obviously unnecessary (since Health Canada flat out refused to dispense/manufacture/distribute/prescribe the BHT-containing OP branded USA OxyContin, which our Food and Drug Administration passed likely without second thought or even considering how the consumers might react to the FDA deciding that they were not concerned about the possibility of giving their own citizens a possible carcinogen).
 
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