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Opioids overdose question

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Yes. It hits you fuckin' hard and is honestly one of the most painful experiences ever, hah. I told the paramedics to just let me die next time because the narcan was so bad.

The shit saves lives, so it's a God send but... it is not a fun time...
 
I guess my experience must be quite the unusual one because I got hit with the narcan, went home and went to sleep for 15 hours. No precipitated withdrawals, no withdrawals of any kind.
 
Since they don't know exactly how much you took of what opiate, I'm guessing they hit you with a lot of narcan to make sure that it brings you out of it. If you didn't go into precipitated withdrawal I'd guess that your agonist dose was quite high, and that when you were hit with the antagonist it made it so that you felt just fine. if your agonist dose was lower, I'd think you would have gone into precipitated withdrawal.

Don't take the above as fact, it was just speculation, and I have no formal training in the medical field.
 
Narcan goes up to the opiate receptors and rips off and opiates and binds onto said receptors. It's instant and if you are opiate dependent you will go into WD, you will have no opiates left in your system.

And yes, it's the worst experience ever. It's like condensing a week of WDs and being dope sick into 12 hours.
 
The severity really depends on how much opiates you took and how much naloxone they give you, but it's generally very unpleasant if they give you a lot of naloxone. I think Venrak is correct is theorizing that if one had taken a high dose of opioids and was given a lower dose of naloxone it would not produce precipitated withdrawals. However, not all overdoses are treated with naloxone. Once I od'd and they just gave me oxygen until I started breathing again then monitored me for a while until they were satisfied that I wasn't going to stop breathing again.

ETA: Also naloxone doesn't last very long - Obscure, did you seriously have precipitated WDs that lasted 12 hrs?
 
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Swimmingdancer,

The first time I shot heroin, a friend of mine shot me up, and totally fucked me. I told her to give me a tiny tiny dose, but whatever it was, was too much. I was flying high for about a minute then just hit the deck hard. I woke up to voices over me from a shot of Narcan that her dealer shot me with.

For the next 12 hours, I had a horrible headache, was constantly vomiting, and just felt like shit all the way around. Since then I've gone into WD several times, and honestly, that first experience was like condensing a week of WDs into 12 hours. Eventually I fell asleep and woke up a day later feeling slightly better, but still not 100%. It took another day to get back to normal. I respect the hell out of Narcan and what it can do, but it doesn't joke around.
 
obscure said:
Swimmingdancer,

The first time I shot heroin, a friend of mine shot me up, and totally fucked me. I told her to give me a tiny tiny dose, but whatever it was, was too much. I was flying high for about a minute then just hit the deck hard. I woke up to voices over me from a shot of Narcan that her dealer shot me with.

For the next 12 hours, I had a horrible headache, was constantly vomiting, and just felt like shit all the way around. Since then I've gone into WD several times, and honestly, that first experience was like condensing a week of WDs into 12 hours. Eventually I fell asleep and woke up a day later feeling slightly better, but still not 100%. It took another day to get back to normal. I respect the hell out of Narcan and what it can do, but it doesn't joke around.
Click to expand...

Interesting... Maybe they gave you a huge dose of Narcan and/or a lot of the symptoms were side effects and/or caused by taking way too much heroin (and it being your first time)? Narcan itself usually only lasts for 45min. But of course the withdrawals can last much longer in people who are already physically dependent on opiates and don't take more opiates after it's worn off. Maybe it was just like a horrible come-down from all the heroin/Narcan or something. I've always wondered whether Narcan can cause prolonged precipitated withdrawals in people who have no dependence to opioids. I've read conflicting info on the topic. When I was given it when I was not physically dependent on opioids, after it wore off I felt the heroin high again, still a bit sick but nothing similar to heroin withdrawals. But I don't think they gave me very much...
 
yeah, from what i've seen, it's fucking aweful even if your addiction is only moderate (is there such a thing?).
i had one first-hand experience with it, an acquaintance of mine ODd in my living room, mainly because he was a huge retard, i had snorted a small line of the gear which i always do before i even consider shooting it, and it was enough to really buzz me, usually this does next to nothing to as the smack around here isn't that good, but this had been cut with god knows what, probably fentanyl, and even though i warned him he cooked up a 'smaller' shot, but since he'd been using forever and i am very on and off with opiods he didn't think it was sensible to listen to me, or try a line beforehand, as i urged him to do. well, he fired home and instantly went into full OD mode, stopping to breathe. i was getting cigarettes, a five minute walk from where i was living back then when that happened. my then-girlfriend instantly phoned an ambulance and started doing cpr, and i came back maybe two or three minutes after the injection. i didn't have any pure naloxone, but a few tilidine pills, which contain 100mg tilidine and 5mg naloxone. i figured that that should work until the EMTs arrive, so i cooked it up, spilling parts and barely filtering it because i was in such a hurry, and then shot him up with it. to my surprise it wasn't instantaneous, as i thought it would be, but he came out of it pretty fast and he was in a terrible way. i mean i've seen opiate withdrawal before, but that was something else entirely. i - probably foolishly - gave him 10mg diazepam and when the EMTs arrived they said that the cpr plus the the shot i gave him definitely helped a lot to save his life and prevent brain damage. i'm still kinda proud of that, although to be honest he was a huge scumbag.

edit: yeah, the half-life of naloxone is something like 63 minutes, which is why they took him into the hospital for a 24-hour observation, and probably to give him more, as the tilidine on top of what he already shot couldn't have been good, as it's much longer lasting
 
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