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Options to quit opiate/oids for good and dealing with PAWS -- Methods, suggestions.

notsmokeymcpot42088

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Apr 5, 2025
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So I have been cutting down on bupe for many years -- am getting near the point of jumping off (Would like to get down to .2 every 36 hours) but I know from experience I am not good with a month of w/ds. (I'm long-term pain soft short term pain hard)

I am sure this thread has been made before but new products and information are around now EX

Sublocaid -- I have heard ppl get off of opiates COMPLETELY using sublocaid and say it was not that horrible.... I am not sure if I could get a shot in a dose small enough it would not send me backwards (that's just me though)
Sr ??? -- A research chemical that has recently became available that binds to your g protein (I don't understand it) someone fill this one out.
Ibogaine
Cold Turkey.
Switch to a longer halflife and taper very slowly (not much different from sublocaid)
Methadone and Suboxone get an honorable mention but that is not the magic bullet forsure (There is none but lets do our best)
Switch from low dose long acting maintenance to low dose short acting opi to end taper

Things that help in the last stages
Immodium
Benadryl / BP medication
DXM
Benzos
Somethin non opi for pain
Neurontin/Lyrica
WATER (You prolly dehydrated)

I ask for help in this thread --- One of my chemistry ppl feel in the SR ??? and explain it in a way that doesn't sound as stupid as mine! Any other methods or suggestions appreciated.

Dealing with PAWS -- I want from triple digit benzo down to 2mg a day so I am constantly dealing with benzo paws -- I do not have a great answer. Alcohol helps, anything that hits the Gabba receptor helps. (Sorry I'm a laymens)
 
Not sure why no one replied yet, it's been a while, hoping you're better. Benzos and gabapentin / pregablin should be at most a 2-3 week supply, ideally rotating.
lofexidine helps, make sure you know the dose (this is the BP medication, aka clonidine, but less affective of BP and addresses the restlesness, a bit of anxiety, sweats, etc. Core symptoms.
Immodium def, helps, not only stabilises yout gut, your gut won't be sending panic signals to CNS (gut-brain axis), keep on therapeutic doses tho, don't allow significant CNS penetration (I do 12-14mg, don't go far beyond it, if it reaches CNS, it's a MOR agonist, will just be counter productive against resynthesizing your receptors again already fucked by bupe.
Scratch Benadryl unless it's dehydroxyzine. Most 2nd gen anti histamines have a counter productive for restlesness and anxiety.
And yeah, liquids, with them electrolytes :)
There's seems to be a pattern that the stress induced by withdrawal can extend its duration and PAWS, so address them responsabily.
 
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