Great replies from all, thanks
IMO, some of waldos suggestions were dosing a little too high for an opioid naive person. I agree with his suggestions for cannabis though, helps naive users with the nausea and also does seem to have positive effects on onset for me.
25mg oral oxycodone is too much IMO, and so is 30mg rectal morphine, especially dosed all at once. I would titrate up to 20mg oral oxycodone and at the most start with a 20mg rectal morphine shot, on separate occasions of course, I didn't mean mixing the oxycodone with the morphine, just to clarify.
Yeah tri - my fave thing about waldo's response is the specificity & detail of it, along with the cannabis recommendations. I'm hoping just a pinch of high-grade sativa will put the spin I'm looking for into the whole experience, though I won't know until I try it. Agree that since I'm such an opiate wuss 20mg
MAX rectal of morphine sulfate or 20mg
MAX oral Oxycodone will be the next step, then the cannabis.
I was surprised to read that you felt that the initial 10mg oral dose wore off quickly. I'm sure it being a low dose had to do with it, but when I take oral morphine it lasts longer than just about all other opiates, but it is MS Contin which is time released, and I just chew it a bit so it doesn't do much in defeating the time release. I'm sure that it was still in your system when you took the additional 10mg rectally, even if the high seemed to have worn off.
Edit: I just read over waldos dosing suggestions and I agree with tricomb that it was too high. Oxycodone is more potent than morphine when taken orally, so it wouldn't make sense to take a higher dose than they had taken of morphine if they were able to get a buzz off the morphine. 15mg of oxycodone would probably be perfect, but it's best to start off at 10mg to make sure you don't get sick from it and also since you might get high enough from 10mg so it would be better to stop there instead of raising tolerance. After 10mg if you need more than increase by 5mg increments every 20-30 minutes.
Tommy - after reading some later replies I agree, the oral 10mg dose was likely still hangin' around in the blood. I'm just too much of a rookie at the time to consider half-life, etc. Just experimenting carefully, but with a bit more know-how now, thanks to everyone here.
A 10mg Oxycodone k56
http://www.drugs.com/imprints/k-56-15462.html is something I'm familiar with and would be taking this time around. No nausea in the past. I can probably manage 1+1/2 for 15mg oral or possibly even 2 of them for a total of 20mg oral next time, and yeah, no way would I mix plugging and oral, it would be specifically either one 15-20mg dose
per session or the other only, never both.
Nice to know from you both about the "legs" on the oral morphine sulfate as well. I really appreciate all the detailed info everyone offers here. Can't get enough information, as I consider this all to be fun, but at the same time, seriously "playing with fire." I do have a nice pill-cutter, so no problem with the 5mg oxy increments.
Morphine has more legs than most other opioids I've found, one rectal shot of morphine in the morning and I'm set for analgesia all day, and this drug has a 2-3 hour half life LMAO, oxycodone which has a 5-6 hour half life doesn't even provide analgesia for me for more than 3 hours-ish.
Yes tri, that's probably one of the most important things you guys have schooled me on so far: being careful (titration) with the preconception that the liquid morphine can be deceptively subtle and more long-lasting, while the oxycodones are more the rock star that comes on stronger but wears off a little faster, though it wouldn't surprise me to find out it's different for everyone. I'm following the "half-life" rules and stats for safety.
Summary: again many thanks to all the above, tri, Tommy, waldo, pbuild etc for all your help. Thanks to you all for sharing all the knowledge, recommendations etc. so I can have safe happy journey(s). All the best.
