OPIATES, occasional use after addiction & what it does to receptors

KaleB541

Greenlighter
Joined
May 13, 2010
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24
Location
UK
Hi all,

I've just come off MMT last month, and a couple of weeks later I got the great idea to do H just recreationally, as a way of interrupting paws, like a vacation. Well I have to say that was a pretty stupid decision, since all of the mental sidefx of paws were literally reset to 0, and I'm just starting to slowly get to the point where I was right before the mini relapse. I even had some physical wd fx, though with lesser intensity.

My question is about recovering your natural opiate system. Do those extra receptors in the brain that were used to getting methadone or H need to go dormant and then die off? How long does it take for this to happen? The way I see it, if you take any opiate at all, even once, you're just reactivating those receptors and setting yourself back to square 0 with healing your brain. Then you might get the wrong impression that you need opiates to feel "normal" where in effect occasional use is what's making you feel abnormal for the other 6 days of the week. I have been off opiates for 10 years prior to relapsing last year so I can definitely confirm that things do indeed go back to the full healthy state, I'm just wondering how does this happen on the receptor level in the brain??
 
hi Kale.. ..glad to hear you came home from your "vacation"!!

i find that it takes around 6-12 months for receptor sites and brain cells to reform/repair them selves after the discontinuation of chronic opioid use. letting us actually interpret our pain and anxiety at clearer state after this period of abstinence.

what happens when opioid are constantly being taken is plethora of opioids are bonding to our op receptor sites our bodies react to this by producing less natural endorphins and actually shutting down opioid receptor sites and changing the structure of cells. when the opioids are suddenly stopped being taken there becomes a shortage of opioids so in return to this insufficiency the body will start to reform receptor sites, restructure cells and start producing more endorphins.

acute withdrawal being the initial shock of the discontinuation of opioids and PAWS being the period of "reseting" to natural settings.

hope this helps. .. and wow ten years that is incredible. you for sure have the strength to forget about that "bad vacation" and move on forward to a "wonderful holiday"!!
 
From what I understand the cell actually retracts the opiat receptor back in through the cell membrane. I saw a good explanation of it in ADD and will try and find it or another but yeah the receptor is actually brought back into the cell membrane. I experienced the shutting down of a massive group of my opiate receptors at four months and three weeks.. one day i just got really pretty tired after only sleeping for like three or four hours a night for months and for three days in a row I slept for like eight to ten hours and each time I woke up my mind was clearer and clearer.. which was amazing to me because i had been high so long that I really had no idea what a clear mind was.

The pain Dr I spoke to about this phenomenon put a time period of seven and a half months for the big cluster of opiat receptors to shut down, but i think its an individual thing. As the amazing and extremely wise pro re nata states:) it is a process that can take up to a year or more and our minds continue to clear even more after that big shutdown that many experience. Also right before the big shut down I got quite the addictive push for a week and I almost caved and went back to methadone literally three days before the miracle so just something to think about.

To get these things to happen you need to be completely opiat antagonist free and after the acutes are over I would not smoke any grass until this process is complete as well as an interesting study of narcon a few years back on people that only where heavy grass smokers resulted in those heavy grass smokers that were administered the naloxone going immediately into hard core withdrawal so that leads me to believe that cannabis must manipulate the opiate receptors and could conceivably delay or prevent the healing that is so amazing.

Also IMO it is hard if not impossible for a person to maintain control of a particular type of substance once we have become addicted to it so please think about the benefits of attempting to use opiates versus the consequences the have had on you. Might want to consider limiting your drug use to substances that are not addictive or who have addictions that are acceptable and jive with your life.;)

Wishing you a quick receptor shut down kale:D
 
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