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  • BDD Moderators: Keif’ Richards

Opiate Tolerance

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blah_blah1991

Bluelighter
Joined
Jul 28, 2008
Messages
286
Location
Aus
Hey guys, i have some questions about opiate tolerance but first off ill start off with my opiate history.

January - March 2009 done codeine about 5 times started at 100mg ended up at 500mg and in the end didn't get much from it.

April 2009 went into hospital for surgery got put onto Fentanyl however the Fentanyl stopped working for pain overnight and ended up making me anxious so they took me off it (Doctor asked if i have previously used opiates i said no as i barely had and the doctor also noted that i had a very large dose of self administered Fent but it really wasn't getting rid of the pain i was in. They then switched me to 40mg oxycontin day and night as well as 2x5mg oxycodone IR 3x a day. I was advised this was quite a large dose for my condition and i had an already high tolerance.

Anyway i had that dose for 2 days then i went down to 30mg twice daily for 3 days (I didnt end up eating that much i ended up eating 15mg +200mg of codeine because i wanted to save the doses for later use) and then over the next 1 1/2 weeks i was taken down to nothing.

Over the next 2 months i went through 200-250mg of oxy that i had hordered and i required about 40-50mg of oxy to get high and feel euphoric and a nod etc.

July - December 2009 I used oxycodone about once a month anywhere from 40-60mg i tried 80mg once and got sick and felt dysphoric.

I then had a little bit of a break and in March i returned to opiates however my tolerance hasn't dropped in fact it has raised a little i was under the impression it would have dropped. In the month of march I probably used 3 or so times first 40mg then 60mg then 60mg with a 20mg topup without getting sick at all. In April i was able to tolerate 120mg (100mg + 20mg booster).

What i don't understand is back in September i got sick off 80mg and now my tolerance is pretty much at 80-100mg being the sweet spot. I must add i never use two days in a row and always leave a week at least between dosages. I have now done H a few times and my tolerance to that seems to be pretty stable (1.5p-2p of china white IV) which is quite high. Now i don't have an extensive opiate use and people who have used much more then me have less of a tolerance. Any explanations for this or do i just have a naturally high tolerance, also how come my tolerance doesn't lower when i have had a month or two break?

Cheers
 
This is the thing with opiate tolerance

You stop using for a long time, the first 1 or 2 times you'll get high, then it always seems to revert back to the way you left off.

When people stop using opiates, when they start again they naturally pick up where they left off really quickly.

Opiate tolerance has never gone away in my experience, except when i've had KAPPA agonists which I won't get into here.


Opiates are the devil man

I've been struggling for a while and im getting better by the day man, I don't wish it upon anyone.

They numb your feelings and emotions... so much in fact that when u don't have opiates you don't know how to deal with your emotions.
 
Yep, the only cure is pure abstinence for a very long period.

When I have been clean for 2 weeks, I would dose oxy, and my dose would be a fraction of what it was. But using for just a couple days in a row, would have me back to using 150mg+ to feel anything.
 
I've heard of people getting high from 10mg of oxy with no tolerance. At one point I was doing 160mg at a time 2 or 3 times a day just to feel normal. That was about 2 years ago. Now I do Oxy maybe once every 2 months, and I need at least 40mg to feel anything, about 100mg to nod, so that tells you that tolerance obviously never COMPLETELY goes away once you have had a bad habit.
 
You people with this crazy high tolerances got problems, let me explain some facts to you guys...

Opiate tolerance doesn't go up just from long term use, it goes up from experimenting with a higher dose. Example: if you are a new opiate user and it takes 15mg of oxy to get you high, you will never need more than 15mg to get high, unless you start messing around with 20mg, then eventually it will void out the 15mg and you just raised your tolerance to 20mg.

Think of your opiate tolerance as a nail with markings on it; 10 20 30 40 50 60 70 80. If 10mg gets you high, then 10mg will always be enough to get you high no matter how long you take it, but once you hammer in the nail deeper to the 20mg line, thats your new tolerance.

So do yourself and your wallet a favor. Don't experiment with higher doses, all you are doing is raising your tolerance, and soon it will take 80mg to equal what 20mg once did, and you will be BROKE.

If you think I'm making this up, think again. I've been on Roxicodone greens (15mg) for 5 years, and guess what, it STILL only takes 1 to feel tons of euphoria, 20mg to nod out. Ive NEVER taken more than 20mg at once EVER.
 
NiteShadeX said:
You people with this crazy high tolerances got problems, let me explain some facts to you guys...

Opiate tolerance doesn't go up just from long term use, it goes up from experimenting with a higher dose. Example: if you are a new opiate user and it takes 15mg of oxy to get you high, you will never need more than 15mg to get high, unless you start messing around with 20mg, then eventually it will void out the 15mg and you just raised your tolerance to 20mg.

Think of your opiate tolerance as a nail with markings on it; 10 20 30 40 50 60 70 80. If 10mg gets you high, then 10mg will always be enough to get you high no matter how long you take it, but once you hammer in the nail deeper to the 20mg line, thats your new tolerance.

So do yourself and your wallet a favor. Don't experiment with higher doses, all you are doing is raising your tolerance, and soon it will take 80mg to equal what 20mg once did, and you will be BROKE.
Click to expand...

Completely false.

If that was true then pain patients would never need to up their doseages.
 
I agree, that is bullshit ^
If tolerance wasn't an issue how do you explain the dope using population of BL just maintaining at 3 bags a day, but still having to up the dose if they can't kick?
Tolerance is tolerance, it builds up against your will, and is an absolute bitch to bring back down. And it's not just opiates.
 
tolerance will go up no matter what or how much you use. you have your tolerance from your opiate of choice, and you have cross tolerance build up from other opiates.
 
Being a long time opiate addict I feel you on this, tolerance is a bitch. IME it takes about 18-36months of complete abstinence for our tolerance to return back to 0. Even then your body is used to it by now, so you will gain tolerance much quicker than you did the first time around. I remember splitting an OC 20 with my girl (snorted) and that made me sick my first time. Then when I got really hooked on those blues after I moved to Tampa I would have to shoot at least five of them to get high (usual IV dose was 180mg, sometimes 210mg when I had the $) and that only took about 2 months of regular IV oxycodone use to get into the 200mgs range.

The things that will raise your tolerance are, the closer together your highs are...do you wait at lest a day between use? 2 days?
Next is how often you raise your dosage. I always liked to push the envelope and try another roxi in my next shot, always just a little more to try and hit that sweet spot.
Then it depends on your ROA, do you take them Orally, Snort them, or Shoot them? IV drug use will lead to incredibly high amounts of the drug just to keep you from being sick.

Really if you took one Roxicodone 15mg tablet orally every weekend only, you would keep a pretty low tolerance for a good while. Now on the flipside If you start shooting that same Roxi and it becomes a regular habit you could see yourself going from 15mg to 150mg in less than 2months.

...hopefully some of that helped out
 
mdmantpa said:
Being a long time opiate addict I feel you on this, tolerance is a bitch. IME it takes about 18-36months of complete abstinence for our tolerance to return back to 0. Even then your body is used to it by now, so you will gain tolerance much quicker than you did the first time around. I remember splitting an OC 20 with my girl (snorted) and that made me sick my first time. Then when I got really hooked on those blues after I moved to Tampa I would have to shoot at least five of them to get high (usual IV dose was 180mg, sometimes 210mg when I had the $) and that only took about 2 months of regular IV oxycodone use to get into the 200mgs range.

The things that will raise your tolerance are, the closer together your highs are...do you wait at lest a day between use? 2 days?
Next is how often you raise your dosage. I always liked to push the envelope and try another roxi in my next shot, always just a little more to try and hit that sweet spot.
Then it depends on your ROA, do you take them Orally, Snort them, or Shoot them? IV drug use will lead to incredibly high amounts of the drug just to keep you from being sick.

Really if you took one Roxicodone 15mg tablet orally every weekend only, you would keep a pretty low tolerance for a good while. Now on the flipside If you start shooting that same Roxi and it becomes a regular habit you could see yourself going from 15mg to 150mg in less than 2months.

...hopefully some of that helped out
Click to expand...

Yea my husband only gets high once a week. He takes 30mg Roxi orally and is straight... his tolerance never changes. Sometimes he kicks up 15mg after dosing to keep his buzz going as well. But 30mg always gets him off.... If he did it more his tolerance would go up.
 
^yeah exactly what I was talking about....you need very strong self-control if you want to dabble in opiate use without building a tolerance, and if you stray even just a little your going to be headed down a long long road
 
I do 20mg/hydro a week tops and my tolerance hasn't changed. But there are times when for one reason or another it doesn't work. It would be easy to say 'oh, my tolerance has gone up" and increase a little.

But what I've learned is DON"T PANIC. Because just keeping the same dose and schedule, in a few weeks my high comes back the same.

The body is a complicated thing and a lack of high is not always due to increased tolerance!
 
i can only speak for myself and i think that i raised my own opiate tolerance. at first i started shooting a half bag of H for a few weeks n that was working well but little by little i added more n more till i was up 2 2 bundles a day..i feel as if i would have stayed at shooting 1 bag at a time instead of 2 or 3 when i didnt need 2 my tolerance wouldnt have raised as much..i feel i pushed it along. idk kina hard to explain does any1 kno what im saying?
 
^yeah, and another thing is there are some people that are not honest with themselves about "tolerance" and "unsatisfied". Trying higher doses will give a new definition of what "high" is for them. The lower doses may actually still be working but now they want to reach the new high each time and say their tolerance has increased, which of course ends up being a self-fulfilling prophecy!
 
First of all, its OxyContin, not "oxyconten". There isn't a ceiling dose orally (like there is with codeine, for example). The ceiling is going to depend on your tolerance to the drug. You're not going too far if you're not getting pain relief.

Remember, however, that when you increase your dose, increase it in small amounts over time. It is much easier to take more than it is to take less.
 
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