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Bupe Opiate Naive person swallowed a subutex

187coopa

Bluelighter
Joined
May 26, 2009
Messages
423
Ok so my dumbass friend took one of my suboxones thinking it was a percocet or something. He just said he swallowd it. This was about 4 hours ago. He has no tolerance to opiates. He said he feels good but im worried that he is gonna get really sick.

Thankfully Im aware that the bio availibilty of suboxone is very low when taken orally so is he screwed or what. He is also an alcoholic and has drank a six pack today.

since its been 4 hours since he took it im pretty sure he is in the clear. and that the effects are on full strength as of now. just looking for some opinions from you guys. He is 275 lb's if that helps any.
 
He should be fine, 10% bioavailability is pretty small. It would be equal to him putting maybe a third of one under his tongue, which is a large amount for a non-tolerant person but probably safe.
 
He should be fine, just make sure--for his safety--that he doesn't dose any other opiate/opioid(s) for at least 48 hours, precipitated withdrawl wouldn't be fun.

However, if it was Subutex rather than Suboxone, he'd be fine.
 
ya it was subutex. He just doesnt do any opiates at all maybe once a year if that. he said he feels really good lol. I can imagine.
 
He should be fine, just make sure--for his safety--that he doesn't dose any other opiate/opioid(s) for at least 48 hours, precipitated withdrawl wouldn't be fun.
No need to worry about precipitated withdrawal as he's taken the subutex first.

Bupe is pretty fucking strong though so as you said he'll be feeling mighty fine for a while. If it's been four hours he should be alright but mixing it with benzos or a lot of booze will increase the risk factor.
 
There is a ceiling effect for the respiratory depression effects of buprenorphine, making it hard to overdose. Combining it with other CNS depressants, though, (like ethanol) can cause overdose.

Keep a close eye on him!
 
i heard a story of a girl who od'ed from 2mg of suboxone and 2mg of xanax once... (obviously non tolerant)

he should be ok but i would keep an eye out
 
^ Bupe may be a relatively safe opiate but it is still a potent drug with depressant qualities. Mix alprazolam into the mix (a potent benzo, and 2mg isn't a small amount) and things could easily go wrong, especially for a small, non-tolerant female.
 
^yea most def. Bupe is a really strong partial agonist...Even a small dose like 1mg is enough to completely throw off 110mgs methadone a day to a very tolerant user with a high tolerance.

give it to someone without an opiate tolerance, or is opiate naive and they cant tell the difference between that and morphine, at least that is what i have read.

As for your friend, who is a dumbass for taking some pill he thought was a percocet lol, he will be fine. as everyone has said, bupe has a low oral BA. just keep an eye on him, at most he might feel sweaty and kinda sick but hes not going to OD or anything.
 
He should be fine, just make sure--for his safety--that he doesn't dose any other opiate/opioid(s) for at least 48 hours, precipitated withdrawl wouldn't be fun.

However, if it was Subutex rather than Suboxone, he'd be fine.

Precipitated withdrawals happen when you take suboxone/subutex after having taken a normal opiate. It is the buprenorphine that causes precipitated withdrawals, NOT the nalaxone. Suboxone/subutex both will cause precipitated withdrawals. If you have opiates on your receptors, and dose either one of those, you will precipitate withdrawals.
 
He should be fine, just make sure--for his safety--that he doesn't dose any other opiate/opioid(s) for at least 48 hours, precipitated withdrawl wouldn't be fun.

However, if it was Subutex rather than Suboxone, he'd be fine.

Taking a full agonist opiate after Suboxone or Subutex is perfectly fine.

It's when you take buprenorphine on top of a full agonist that precipitated withdrawal happens.

Subutex can still cause precipitated in the exact same way Suboxone can.
 
good thing he swallowed it!! could be in trouble otherwise. it does say in the literature "death has been reported in non tolerant, nondependent individuals" thats kinda scary
 
Taking a full agonist opiate after Suboxone or Subutex is perfectly fine.

It's when you take buprenorphine on top of a full agonist that precipitated withdrawal happens.

Subutex can still cause precipitated in the exact same way Suboxone can.

Yea except the subutex will block the full agonist unless he took a low dose of subutex.
 
good thing he swallowed it!! could be in trouble otherwise. it does say in the literature "death has been reported in non tolerant, nondependent individuals" thats kinda scary

You would *have* to combine it with another CNS depressant; on its own, for an otherwise healthy adult, buprenorphine on its own won't kill you.

Yea except the subutex will block the full agonist unless he took a low dose of subutex.

He took it orally, though. Even if he ate a whole 8mg of Subutex, orally speaking, that isn't a lot of buprenorphine at all. He could still use full agonists, and feel them, on top of this.
 
Yeah I swallowed 16mg of suboxone one time when I was younger, not knowing you shouldnt swallow them, with very little tolerance. Didnt know what they were, just knew that they were supposed to fuck you up. Anyways I was in heaven for about 10 hours, best feeling in the world. Then I got home and puked my brains out for almost an hour straight. I know this post is old but he should be fine, although I don't recommend this at all. Taking any amount of suboxone over 2mg I would say, without a tolerance, could potentially be dangerous.
 
He should be fine, just make sure--for his safety--that he doesn't dose any other opiate/opioid(s) for at least 48 hours, precipitated withdrawl wouldn't be fun.

However, if it was Subutex rather than Suboxone, he'd be fine.

Not true,buprenorphine in itself is a powerful antagonist in itself to the point that the nalaxone in suboxone is redundant (bupe alone makes you sick if introduce it to a full agonist opiate dependent system while not in full withdrawal)
But then again in this guys case its the other way around..buprenorphine is present in his system..that means any introduction of full agonist opiates in the next 24/36 hrs would just be diminished or blocked(bupe has one of the highest affinities for the opiate receptors making it perfect for a maintenance drug)..in short..he wont be sick in regards to the bupe no matter what he does..he will just waste/use more money(arguably the same thing)
 
If this guy is non dependent on opiates/opiods even if he took a full agonist first then took Bupe an hour later, they would not go into WDs. For somebody to go into WDs they have to dependent on said substance to where there is a net decrease in stimulation of receptors above baseline(nondependent).

They only time Bupe will cause PWDs is if a person is dependent on full agonist's for some time and will go into WDs by themselves if they don't keep redosing.
 
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