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Opioids Opiate Binding of Oxycodone/Hydromorphone/Fentanyl.. Help please..

ThePharmacist25

Bluelighter
Joined
Sep 22, 2008
Messages
378
Location
MA
I am seeking information on binding properties of these three opioids:
Fentanyl Citrate
Hydromorphone HCl
Oxycodone HCl

Basically I am looking to see if the stronger opioid would 'kick off' the weaker of the two. My concern is that my Drug Testing only tests for Oxycodone HCl and Morphine Sulfate (or Heroin). The last time I took ANY Oxycodone (30mg) was on Saturday June the 30th, then yesterday the 1st of July I did Hydromorphone (2mg), and today I am doing a Fentanyl Patch. Only the Oxycodone shows up on my Quick-Cup test (as far as I know), and there is NO general Opiate Reference Point on the test either.

So would the Oxycodone be more prone to be removed from the mu-receptor due to the other two, stronger, opiate?

Thank you for taking the time to read and perhaps reply.. I appreciate it..
 
You know what, there IS A LIST of opiate binding affinities. I lost the link, I will try and find it, but I am sure someone else on this site will post it up before I do

Ki values I believe they're shortened to.
 
Thank you! I will be checking in periodically.. I appreciate that! Anyone else that would like to jump into the convo, please feel free! Thanks again..
 
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