Opioids Opana

[Misscruella]

Hi,

I'm new here. I was just prescribed morphine ER because my insurance won't let me fill a prescription for opana ER that my doc prescribed me, it wants me to try the morphine ER first before I can get the opana. I have an illness that causes muscle, joint, bone, and tendon pain and I've tried everything so now my doctor is having me try the morphine ER. My concern is building a tolerance to opiates. Does everyone eventually? I am on 15 mg rught now I am instructed to take it once a day but I probably take it every other day.

Is morphine ER much different than opana ER? Is one better for my concern with building a tolerance?

And one more question, a woman I know with the same illness reccomended me to order a drug called Kratom. Is this drug helpful I'd you are worried about building a tolerance? Will it be just as strong as the morphine? Thanks

 

[juke007]

Hi there,
15mg is not a high dose, and you seem intelligent enough to abstain to dosing every other day, try to take it only when you need it. Yes, everyone builds a tolerance to opiates when taking them on a regular basis, but with your method I am guessing that your tolerance levels will take their time building up.
I have no answer for the Opana-morphine comparison question because I haven't taken Opana and have only used morphine recreationally.
Educate yourself about the kratom, maybe start with wiki, there are many other people here who have experience with the opana and kratom, be patient, surf this forum, and try and sort out the intelligent replies from the silly ones.
Sorry I don't have concrete answers for you, my point is: educate yourself and take your time before making a decision.
good luck

 

[rules]

if your question is whether or not tolerance always builds? yes. it always builds. if you take opiates constantly, your tolerance will sky rocket. concerning the differences between morphine and opana. well, opana is stronger hypothetically, but the BA of both of them orally kind of sucks. opana's is worse if i'm not mistaken. so you'd have to take more opana than morphine to get the same effects orally. IV is a whole different ball park.

 

[Tommyboy]

10mg of morphine is equal to about 1.4mg of Opana (oxymorphone) when taken orally [source]. Most people report that Opana raises your tolerance more than other opioids, so if that's a concern then maybe you should stick to the morphine.

 

[tricomb]

From personal experience, I think that morphine ER is a better pain killer than the current formulation of oxymorphone ER, which is kind of unreliable. I've noticed that Opana ER has a choppy up and down uneven time release, plus it upsets my stomach just like the reformulated OxyContin.

I think you'll get better pain relief from the morphine plus it's much cheaper, although 15mg Morphine Sulphate Extended Release is a tiny dose, what dose did your doctor want you to be taking per day in Opana ER?

Both Morphine and Oxymorphone are amazing analgesics, their pain killing properties are not in question. I think that more of the issue here lies in the time-release, of which Morphine ER still has a good one, and Opana ER's time release has been reformulated with so many intents on preventing abuse of the medication that it hinders the even distribution of the medication for patients who are not abusing it.

So bottom line, I think it's good that you try morphine ER first, it's super cheap, super effective, potent, and overall very reliable.

 

[rules]

10mg of morphine is equal to about 1.4mg of Opana (oxymorphone) when taken orally [source]. Most people report that Opana raises your tolerance more than other opioids, so if that's a concern then maybe you should stick to the morphine.

you're absolutely right. i completely disregarded that oxymorphone is a much more potent analgesic than morphine and said that you'd need to take more oxymorph than morphine to get the same effect because the BA of oxymorph is even worse than morphine's. please disregard my previous comment. i'm sorry. i'm pretty high.

 

[macd610]

I'm not sure if my input here will be helpful, as I haven't taken either of these drugs in extended release form. However, I've been on both Morphine and Oxymorphone (Opana) in the past-Morphine dose was 90mg every 4 hours and Oxymorphone 30mg every 4 hours. I took the Morphine for a couple of months, the Oxymorphone for about 1 month.
I know many people favor Opana over Morphine, but for me the Morphine actually gave me MUCH better pain relief. On the other hand, I definitely felt much more euphoria and wooziness on it too, and I know that's something you want to avoid.
As others have stated, Oxymorphone is "stronger" than Morphine....You can also see peoples' opinions can vary greatly on subjects such as this.
Try not to worry too much. At least you know that if the Morphine isn't right for you, your MD has already figured out the next step. For me, not knowing causes lots of stress alone.
Sorry I can't answer some other questions, but your'e getting great replies from some very respected members of BL

 

[djtiesto83187]

I would get the opana if possinle but morphine is a fine substitute.

 

[tricomb]

I would get the opana if possinle but morphine is a fine substitute.

Care to explain why?

 

[CasketLottery]

Oxymorphone is indeed choppy with its time release. I tend to find that Morphine Sulfate (MS Contin) is a better alternative to ANY narcotic opioid medication. 15 mg is a very small dose though. Your best bet would be to just do what your doctor recommends..

 

[Misscruella]

Oxymorphone is indeed choppy with its time release. I tend to find that Morphine Sulfate (MS Contin) is a better alternative to ANY narcotic opioid medication. 15 mg is a very small dose though. Your best bet would be to just do what your doctor recommends..

I usually follow doctors orders, but in this situation I don't think taking a narcotic everyday if most people build tolerance like some some of you say, is the best idea. I think I'll stick with the morphine. I just want to know how often I should take it so that I don't build a tolerance. Is every other day ok? Nobody answered my question about Kratom. Does anyone know anything about Kratom?

 

[tricomb]

I personally have no experience with kratom. Every other day will still result in a tolerance, all opioid pain killers will cause a tolerance, whether taken daily or not, morphine is also highly addictive.

It's still great if you can skip days between dosing, but honestly I doubt that will happen, you're going to build tolerance no matter what, even if you took it once a week. These medications are meant to be taken daily, it's supposed to be for around the clock pain, but if you can skip days without discomfort from pain and/or withdrawal symptoms, that's great.

 

[lds324]

Everyone develops tolerances, some faster than others. If he wrote a script and told you to take narcotic painkiller of any sort on a regular basis, the doctor expects that, eventually, you will need to take a higher dose. This is why there are different dosage pills. 80 mg of oral oxycodone would very likely kill an intolerant user, but there are pharmaceutical companies that produce 80mg OC pills for chronic pain patients that need higher doses. Your dosage will get bumped up and if you have decent insurance it wont cost more than a few more bucks per month. Addiction wise, only taking your pain management meds every other day won't stop you from getting addicted. Read enough BL / erowid and youll see countless stories of people using once every two weeks for months and developing addictions anyway.

Follow the doctor's orders to the letter. If you skip a dose, don't take an extra pill or two the next dose. Don't start snorting, plugging, or shooting your pills. This is where an opiate dependence turns into a balls out nightmare of an addiction.

As for meds, I wouldn't say that any one med is "stronger" than another. Pain killer strength is a complicated topic. It's not a question of how far a gram goes or how much pain is relieved in relation to how close you are to overdosing. The question is how much of what a doctor will prescribe as well as which pain meds work better for you. Some people have better reactions to certain drugs. 40 mg of oxycodone should in theory relieve more pain than 15 mg of morphine, but no doctor would offer those two choices.

 

[tricomb]

What do you mean no doctor would offer those two choices? 40mg of oxycodone is equipotent to 60mg morphine, not 15, so of course it's going to have better pain killing effects.

 

[HaZeX]

It's still great if you can skip days between dosing, but honestly I doubt that will happen, you're going to build tolerance no matter what, even if you took it once a week. These medications are meant to be taken daily, it's supposed to be for around the clock pain, but if you can skip days without discomfort from pain and/or withdrawal symptoms, that's great.

This! If you can skip a dose, do so. You never know when a rainy day will come, maybe your Dr drops you, who knows. Ive started doing this within the last month and I have 15days worth of Roxicodone saved just in case.

 

[lds324]

I forgot where I was going with the post and I used a pointless example. Better example would be codeine and morphine. I haven't used codeine before so I don't know what doses the pills come in, so I'll assume they come in 40 mg pills. 100 mg of codeine = 15 mg morphine. Unfortunately, in this scenario, you can't get 100 mg of codeine exactly. Instead, you get to pick between 120 mg codeine and 15 mg of morphine. If the opioid conversion chart converts directly to effectiveness as an analgesic, then you would get more pain relief from the "weaker" drug. This is all in theory, assuming the chart is exact.

So the tl;dr version (for a short enough paragraph) is that we need to know how much kratom you would get to determine if it might be a good choice.
I would assume he would get 5mg of opana, correct me if im wrong.

 

[mrflowers00]

nothing kills my pain like oxycodone most wouldn't agree (at least on BL) but most the people i know who use opiates/opioid drugs say that oxycodone works best but opana works very well too i find that morphine on the other hand gives a dirty high and little pain relief hydromorphone is what i ask for in the hospital and if it lasted longer would be my favorite opioid but i IV

 

[Misscruella]

What is a dirty high? I feel like my body gets very heavy when I take it, then that feeling goes away a little later and my body feels very light. I hope I'm making sense to you. I'm not sure if I understand addiction completely, I've come to understand tolerance. Addiction means that after awhile I may feel like I cannot function normally without the drug, and I want it really bad even though I may not need it right? I dont feel that way now, but I am very strong willed and dont want to become an addict. Though I'm sure many people that are addicts don't go into using drugs thinking they will be addicts one day. I only use the morphine 4 times a week at the most, but you say I will build a tolerance. How long will this take approximately? Once you build a tolerance, is there any going back? Like if I stopped the drug completely for a period of time, would that tolerance be erased kind of like a blank slate?

 

[scottd420]

you're absolutely right. i completely disregarded that oxymorphone is a much more potent analgesic than morphine and said that you'd need to take more oxymorph than morphine to get the same effect because the BA of oxymorph is even worse than morphine's. please disregard my previous comment. i'm sorry. i'm pretty high.

Exactly, conversion calculations are done by comparing the BA relative to how strong the drug is. You can't determine which dose is stronger just by looking at the bioavailabilities. BA is just a unit measurement (A mg/B mg=C% where A=oral or nasal, B= IV) of absorbtion compared to the strength of an IV dose. Haha, if calculations were that easy there would be a hell of a lot more pharmacists around, jokes.
If you already know that feel free to ignore it, I figured I'd just try to make it more visual. I've made the same mistake in the past when I was learning about stuff. It kinda reminds me of molar calculations (g/mol) in chem. Ahh good memories.