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Opana ER & Sodium bicarbonate

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Greenlighter
Joined
Nov 22, 2010
Messages
6
Hi all,

I'm in chronic pain & prescribed Opana ER. I was on OxyContin, until the change in formulas, & the new formula (OP) didn't work at all for the pain I'm in. I was switched to Opana ER, at a much higher dosage. These haven't done much at all until I had what seemed to be an intestinal blockage.

When I went in for an upper GI series w/ double contrast (sodium bicarb crystals in water with barium swallow) , I was higher than a kite later in the day. I tried sodium bicarb at home a few days later, then a few more times after that (I used less than was used in the study) and the Opana ER worked! Any idea as to why?

I clearly had/have some intestinal problems & throwing up for 3-4 weeks was VERY acidic before this. I'd gotten the blockage cleared up before the study.

I had tingling in my hands, arms & face a few days after I had the test, and needed to sleep it off.

I'm curious as to why this medicine works when I take sodium bicarb & it doesn't (or at least not very well) when I don't. I'm not looking to get high. I just want the pain under control & safely. Any ideas as to how to dose this & is it safe? I would think so, as the doctor that ordered the test knows what I'm taking & how much. I don't want an accidental overdose trying to control the pain I'm in.:|

Any chemists in the house that can explain this?

Please PM me if you have an answer!

Thanks!
 
I take Opana ER for chronic pain. It was a really low oral BA. I snort mine.. it lasts just as long, doesn't get you high unless you do a recreational amount and it works great for the pain. They are in the process of making an Opana Nasal spray for this reason. If you want to talk about it PM me :)
 
Perhaps the low bioavailability is caused by it being destroyed by stomach acids and the bicarb is neutralizing some of the acid? Pure speculation.
 
fryingsquirrel said:
Perhaps the low bioavailability is caused by it being destroyed by stomach acids and the bicarb is neutralizing some of the acid? Pure speculation.
Click to expand...

I think you're onto something here.. Kind of like fentanyl is destroyed by stomach acid which is why they can't make a pill formulation..
 
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