In my opinion it is worse than alcohol and weed. The side effects from doing ecstasy every weekend are more severe than drinking or smoking weed in the weekends. Not just memory loss as you said, but also depression, anxiety etc etc.
i agree to this, every weekend use has given me problems that alcohol and doap never gave me, id have to be smoking or drinking everyday to feel the same drained feeling one night on pills would leave me feeling. all depending on how much drank, smoked, dosed, etc.
also I've done many pills not knowing the contents, so unless your just getting mdma dose in your pills, you don't know what other problems could come about.