Tylenol has no psychoactive effects, high doses of it can cause liver damage. The doses of NyQuil you would have to consume for any psychoactive effect from the alcohol, DXM or doxylamine in the NyQuil would mean huge doses of Tylenol (APAP). It's not worth it. Any effect you would get would be a mixture of stupor from doxylamine overdose, nausea from the DXM, anxiety from the caffeine in the energy drink, and serious liver damage from Tylenol/Acetaminophen/APAP.
-We don't allow questions asking "how do I get high?" or "what should I take?"
NyQuil has lots of ingredients, mixing it with caffeine (from an energy drink) is dangerous and stupid. Don't do it.
I'm closing this thread now, please read the rules and PM me if you have any questions.