Nucynta pharmacology? What does it more closely resemble, act like? Drug class???

[painenduser]

Hey guys, not sure if this falls under ADD or BDD, but here goes. I have been googling and looking in here for a while now to try and understand this drug and I'm not finding much thats useful other then this link here in Blue.. http://www.bluelight.ru/vb/threads/450139-Has-anyone-had-personal-experience-with-Nucynta-Tapentadol

What I am trying to find out is what type of drug does nucynta more closely resemble? I know is an "mu antagonist" and I really have no clue what that means, but is this drug more like a morphine? or more like a tramadol? I honestly do not know. I do recall I tried to take some when I was out of my dilaudid and they certainly did not help slow or stop any WD from the dilaudid and they did little for the pain, but I'm back in the same boat and I have some and I'm out of my dilaudid again so I am wondering if I just need to take more then 150mg's or not if that would even help.

So basically has anyone figured out what this drug is like, as far as to what it more closely resembles from a pharmacology point of view? Are there any other drugs that are in the same class? And what exactly is an mu antagonist? Does it act on the brain differently the an opiate does? Im just a little confused if you can help me that would be great.

Thanks!

 

[bpayne]

it would be closely related to tramadol but a bit stronger and for hydromorphone withdrawal you would need to take a great deal more than 150 mg but I'm not sure of the safety concerns of doing so as it is an atypical opioid like tramadol is and has snri qualities meaning there could be more at stake than just a large opioid dose here

 

[painenduser]

So Nucynta can act like an snri? or does it have additional active meds other then the opiate? And also I am on the Fent patch so I have plenty of fent in the matrix and the dilaudid, but Im out of my dilaudid so that's why I was wondering if somehow some way the nucynta I have would do anything for me because I have a very high tolerance to Nars. But thats a different story for a different day

Oh and on note of stupidity, and since I have never taken tramadol I have no clue what that's like either lol

 

[laCster]

tapentadol is a NRI and an opiate-agonist. it's like tramadol, but more powerful.
http://en.wikipedia.org/wiki/Tapentadol

 

[Cane2theLeft]

laC - since you edited your post, it made the last 2 unnecessary so I UA'd them. Cheers

 

[Doug2113]

A mu-agonist means that it induces the mu-opioid neurotransmitter receptors. It being a mu-agonist simply means that it is an opioid, but yes, as stated above, it does have NRI activity; I'm not sure of the serotonin activity, but it definitely has norepinephrine activity.