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Nourytien, an ancient medication.

emkee_reinvented

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ingredients:
o-oxy-benzomidum
acetyl-p-phanethtidiaum
1.3.7 trimethylxanthinum
1.phenyl 2.methylaminopropanoli
bromoisovalerianylureum

Nourytien brand name or product name

to be taken 1 or 2 tablets

the details:

after an family member died my mother kept an very old medicin container he had, cause it looked so antique. well i was very interested, mostly in the first 2 and last ingredient, and wrote down the details. i am not looking for recreation here, just wanting to share with you what i found. and i am hoping to kinda figure it out what this could be indicated for, out of curiousity. this medication was bought or prescribed in the netherlands.

there were no numbers on the ingredients. so anything about the actual effects would be guesses but i am curious if it could have been abusable if the ingredients would be there in the right dosages.

the last ingredient i recall being mentioned in a thread from hammilton about a bromo valerian analogue, but a search turned up nothing so correct me if i am wrong.
 
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the active ingredients would appear to be bromisoval and pseudoephedrine.

bromisoval is a ring-opened barbituate type sedative

220px-Bromisoval.svg.png
 
This abstract doesn't seem correct. This product isn't a "bromide-containing" it's a bromine containing sedative. The bromine atom won't be liberated though (right?) so it can't produce brominism.

Full Abstract
BACKGROUND: Bromides are still sold as sedatives, antitussives, and anticonvulsants in many countries. Bromovalerylurea is a bromide-containing sedative-hypnotic that is occasionally combined with non-steroidal anti-inflammatory drugs in over-the-counter products. Chronic intake of excessive bromovalerylurea can produce bromide intoxication, but acute bromovalerylurea intoxication presenting with myoclonic jerks has never been described. CASE REPORT: A 23-year-old woman was brought to our emergency department with unusual drowsiness. Her physical examination was normal except for frequent myoclonic jerks in all extremities that could be triggered by moving the patient or by noxious stimuli. Initial blood tests results were normal; the serum bromide concentration was 81.0 mg/L (reference <10 mg/L). Treatment with intravenous normal saline and furosemide resulted in gradual improvement in her drowsiness and myoclonic jerks. By the second hospital day, she was normal. A brain magnetic resonance imaging (MRI) was normal. At a 2-month follow-up visit, the patient had no neurological sequelae. DISCUSSION: Chronic bromide intoxication caused by long-term abuse of bromovalerylurea may present as psychiatric or neurologic abnormalities. Our case of acute bromovalerylurea intoxication presented with severe myoclonic jerks and lethargy. The serum bromide concentration was similar to the reported concentrations in acute bromide intoxications. Treatment with normal saline and diuretics results in increased clearance of bromide and an improvement in clinical effects. CONCLUSION: Myoclonic jerks may be one of the major presentations of acute bromovalerylurea intoxication. Physicians should consider bromide intoxication in the differential diagnosis of the causes of myoclonic jerks.
 
Yeah, the structures are completely different. You mean propranolol, correct? Obviously isn't not propyl alcohol.
 
so assuming this part still stands Bromovalerylurea is a sedative-hypnotic. their is pseudoefedrine and some form of caffein, 1.3.7 trimethylxanthinum. nice!

the first two must have some sort of action, no binders and fillers were written on the label of the tube. so the purpose will stay an mystery for a while, thanks.
 
Haha, google just brings us back to this thread :D

kinda freaky when its the only result. i have been braining somewhat could acetyl-p-phanethtidiaum, be

Phenacitine
Synonyms: N-(4-ethoxyphenyl)-acetamide; Acetophenetidine; p-Ethoxyacetanilide; Para-phenacetin; para-Acetophenetidide; 4'-ethoxyacetanilide; p-acetophenetide; p-acetophenetidine; acetophenetin; acet-p-phenalide; p-acetphenetidin; acet-p-phenetidin; N-acetyl-p-phenetidine; phenacet; pyraphen; aceto-para-phenalide; aceto-para-phenetidide;
1-acetamido-4-ethoxybenzene; acetylphenetidin; coricidin; empirin
compound; phenacitin; phenazetin; paracetophentidin; Phorazetim;
N-Acetyl-4-ethoxyaniline
from http://students.chem.tue.nl/ana21/Safety/Chemical Properties.htm

which leads me to here http://students.chem.tue.nl/ana20/Summary.htm

"Phenacetine is a painkilling drug. Since 1984 it isn't allowed to use phenacetine in painkillers anymore because of its harmfull side effects"

which could mean its an painkiller of some kind?
 
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