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Misc nortriptyline--Chest pains

HaZeX

HaZeX

Bluelighter
Joined
Mar 5, 2011
Messages
384
Just have a question that maybe some of my fellow BL'ers can help with.

Ive taking amnitriptyline 50mg in the past with no problems, my Dr changed me to nortriptyline 50mg, and tonight I took it, and within 20minutes I started to feel I would think chest pains, like a heavy/tight feeling in my chest. I decided to make myself throw up, and I felt 97% better, I still feel maybe a slight bit of heaviness in my chest.

Im obv. not going to take this pill again but wanted to here what you all thought.
 
I just wanna bump this..I know it isn't typical OD stuff. But most of you OD guys/gals know your shit.
 
Are you definitely sure the tight chest/nausea was down to the nortiptyline? If so I'd highly recommend you report back to your doctor at the next available opportunity and get your prescription switched again. Whether what you felt was dangerous or not, if you cannot live with the effects you personally get then you definitely need a change of drug.
 
^^ This! I'm on nortryptiline. Unlike how i react to amtryptiline which makes me too tired to function, nortryptiline is the opposite. I've found I have to take it in the morning (unlike the reccomended at night) with a beta blocker to feel normal. This is an unsual but not completely uncommon reaction, the side effects list suggest it could go either way, it is just rarer to go my way. This is because it makes my heart race. Is that what was happening to you? It is a high dose to be started on, I worked my way up from 10mg and am now on 75mg.

Your doctor is the only one who can really help you here. But I would reccomend trying them one more time to see if you are certain the reaction is the meds. Why were you switched by the way?
 
Albion said:
Are you definitely sure the tight chest/nausea was down to the nortiptyline? If so I'd highly recommend you report back to your doctor at the next available opportunity and get your prescription switched again. Whether what you felt was dangerous or not, if you cannot live with the effects you personally get then you definitely need a change of drug.
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Im thinking it was the Nor. because its started happening within 20min. of taking the pill. I did not combine it with anything else, only other thing I've taken in the day was Oxy 3hrs before, and Opana 2 hours before. I did call my Dr, but they were out of office because of Memorial weekend, so I only got the covering Dr to call me back, they only said to stop the medication. But I will be calling again Tuesday and speaking to my regular Dr.

madog11 said:
^^ This! I'm on nortryptiline. Unlike how i react to amtryptiline which makes me too tired to function, nortryptiline is the opposite. I've found I have to take it in the morning (unlike the reccomended at night) with a beta blocker to feel normal. This is an unsual but not completely uncommon reaction, the side effects list suggest it could go either way, it is just rarer to go my way. This is because it makes my heart race. Is that what was happening to you? It is a high dose to be started on, I worked my way up from 10mg and am now on 75mg.

Your doctor is the only one who can really help you here. But I would reccomend trying them one more time to see if you are certain the reaction is the meds. Why were you switched by the way?
Click to expand...

I was on Amni. prior, a dose of 50mg. Only reason I wanted to switch was because of sedation that last into the next morning (Taken at bedtime). My dr. said both are both similar pills, just the Nor. has less side-effects. My heart wasn't racing, I took my BP and it was 92-resting.

Honestly I don't want to try it again, Right now I started the Amni back up the next night, which all has been good--minus the sedation like I said.
 
My advice would be try taking 10mg if you can and go from there. In my opinion the nor is ALOT easier to handle side effects wise. It may just be you shouldnt have been started at such a high dose.

I found ami did nothing to help my pain either and the side effects are huge. Nor is stronger in a way because it is the active metabolite in ami without all the crap. Which means you are not allergic to it for definate. Talk to your doctor as soon as you can too, as he will know better knowing your history. What mg are the pills you have? If you can try 10mg, or ask your dr for 10mg pills. Ami is such a difficult drug to cope with side effects wise, if nor can help you, you should try it at a lower dose.
 
There is a chance the nortriptyline interacted with the oxy and opana that were still in your system. More likely to have caused additive respiratory depression than anything else, though.
 
madog11 said:
My advice would be try taking 10mg if you can and go from there. In my opinion the nor is ALOT easier to handle side effects wise. It may just be you shouldnt have been started at such a high dose.

I found ami did nothing to help my pain either and the side effects are huge. Nor is stronger in a way because it is the active metabolite in ami without all the crap. Which means you are not allergic to it for definate. Talk to your doctor as soon as you can too, as he will know better knowing your history. What mg are the pills you have? If you can try 10mg, or ask your dr for 10mg pills. Ami is such a difficult drug to cope with side effects wise, if nor can help you, you should try it at a lower dose.
Click to expand...

The Nor. are capsule so I can't measure out a dose of 10mg, I have no idea how much powder that would be. I have the 50MG capsules. Ill bring that up about trying a lower dose, maybe that was the reason.



Albion said:
There is a chance the nortriptyline interacted with the oxy and opana that were still in your system. More likely to have caused additive respiratory depression than anything else, though.
Click to expand...

Honestly, I don't think so. Ive been on the Amni about a year now, and always dosed it with my opiods. That night that it happened about an hour later I railed 10mg of OxyM and did 150mg's of OxyC, I usually dose more. I had no signs on CNS depression and maintained a steady and normal pulse, mind you the OxyC was with chronic dosing. My breathing wasn't affected by the Nor. It was a tightness/heaviness in my chest, thats the best way I can describe it. I didn't have trouble breathing at all.


Thanks for helping out and getting ideas out there!
 
HaZeX said:
Honestly, I don't think so. Ive been on the Amni about a year now, and always dosed it with my opiods. That night that it happened about an hour later I railed 10mg of OxyM and did 150mg's of OxyC, I usually dose more. I had no signs on CNS depression and maintained a steady and normal pulse, mind you the OxyC was with chronic dosing. My breathing wasn't affected by the Nor. It was a tightness/heaviness in my chest, thats the best way I can describe it. I didn't have trouble breathing at all.
Click to expand...

As I said, you have to be aware that techincally you're taking a higher dose now so both drugs could have played a part in it. My doctor started me at 10mg and moved it up 10mg once a week until I was at the correct dose. That made the transition very easy. The only side effect I have is I get lightheaded when I stand up to quickly now. But that is a mix of the nor and the beta blocker i take, and it's worth it to be pain free!
 
madog11 said:
As I said, you have to be aware that techincally you're taking a higher dose now so both drugs could have played a part in it. My doctor started me at 10mg and moved it up 10mg once a week until I was at the correct dose. That made the transition very easy. The only side effect I have is I get lightheaded when I stand up to quickly now. But that is a mix of the nor and the beta blocker i take, and it's worth it to be pain free!
Click to expand...

Yeah I know, I wish my Dr would have said something. What do you think 50mg Amni is equal to for the Nor.? What exactly is the beta blocker for? Wonder if I should just open the capsule and half it making it 25mg?
 
I've never seen it in capsules. So thats unusual to me, i'd wait to speak to your doctor on that. I don't think there is an equivilancy for it. It is stronger but that is because it is the active metabolite in ami and nothing else. Is the capsule supposed to be time release?

I would still suggest starting at 10mg and working up. My doctor is great, but very cautious. Yours might have thought you would be ok. The beta blocker is because I am one of the few that gets a racing heart, insomnia etc from the nor, so I went and asked for a beta blocker. Now it's perfect. But as I said before, my reaction is rare and more so because ami had such a bad effect on me in the opposite way.
 
This is exactly what mine looks like
Nortriptyline%2050%20mg-TEV.jpg


No it is not time released, Mine is made by TEVA.

Good point, when I call in Ill explain to my Dr and see what they think, if they want to continue it ill just ask to be started as low as possible and titrate up. The only reason I wanted to make the switch was because the Amni was making real tired, The Nor. is not supposed to do this as you explained it since its more "pure". I doubt I would need a beta blocker then since I don't get those affects from the amni/nor like you did.
 
Like i said, ami actually made me so tired i couldnt last 3 days on it. Nor was a last resort, which seems crazy to me as it has less side effects. You'll know if as you are upping the dose you get a racing heart, i doubt you will though. However, it might be better to take it in the morning as it is unlikely to make you tired.

My situation is rare. But i think working up from 10 it may actually work great for you.

I've not seen the capsules. Mine are orange and round pills with foreign writing all over the box lol... guess they aren't made here in the UK for some reason!
 
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