norbuprenorphine

[phr]

Sounds exactly like precipitated withdrawal to be as well.

 

[CharlesIV]

Moderate CYP3A4 inducers-

aminoglutethimide, dexamethasone, glucocorticoids, glutethimide, griseofulvin, nafcillin.

Stronger CYP3A4 inhibitors-

aprepitant, carbamazepine, efavirenz, ethosuximide, garlic supplements, modafinil, nevirapine, oxcarbazepine, phenobarbital, phenytoin, primidone, rifabutin, rifampin, rifapentine, and possibly even St. John's Wort.

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Hmmm, i'd be interested to hear if anyone experiments w/ this and see's any added recreational value to buprenorphine as a result... garlic supplements are easy enough to get ahold of; and so are a number of those other chemicals. I know for a fact cimetidine worked effectively at inhibiting the metabolization of methadone; it would draw out the duration of its effects for me. But i've never really experimented w/ inducers.

I can personally attest for this to WORK!!! :] Actually I have my dose in my mouth & up my nose right now...

What I have found to work is: An hour or so before taking your bupe take a handfull [say five or so]of Garlic pills [the ones that don't smell like ass of course], about 600-900mg of Stardardized St John's Wort, 100 mg of Benadryl and to top it all off a xannie bar...

Then an hour after... repeat!

I usually do eight mg sublingually and snort eight mg....

I know it sounds crazy as hell but I get hella bored on sub maintanence. And I DO NOT recommend anyone to do this. Ever.

 

[JahRed24x]

^^ Yeah I have read lots and lots about using St. Johns Wort to make the suboxone last longer/give better peak effects. I tried it once and didn't notice much and just kinda forgot about it. Whats up with the garlic pills though? what the hell does garlic do for suboxone?

 

[Animoe]

No this wasnt withdrawal! Ive been an oxycontin addict for 3 years now and have been in withdrawal, i have also beenin withdrawal from taking my sub to early and this wasnt withdrawal

What you experienced was 100% precipitated withdrawals. They're not like normal withdrawals, they'll straight up make you delirious because the pain can be that bad. I've done the same thing as you, I didn't wait long enough at all when from my last dose of Methadone before I took Buprenorphine and I just lost it. I was on the ground in the fetal position in the worst pain I'd ever felt and that shit didn't subside for a long time. I couldn't even focus on what was going on through the overwhelming pain, both physically and mentally..
Precipitated withdrawals can be many times worse than regular withdrawals in terms of intensity