Bupe No effect from 16mg suboxone snorted

[pixies+]

Narcan lasts maybe 2 hours methadone lasts 30 so that answers why this person needed more doses of narcan

If methadone still in your blood stream it does not matter how much you give

This story also doesn’t sound right not saying it’s made up but when this situation occurs you’re supposed to be just be hooked up to a continuous narcan drip not be given dose after dose lol

Yeah I understand that… something wasn’t making sense in my head.. nothing unusual lol

 

[Voxide]

Yeah I understand that… something wasn’t making sense in my head.. nothing unusual lol

It can be a lot to take in for sure
Not that many people know the ins and outs of it. Feel like most people still think Naloxone is the reason for precipitated withdrawal when taking subs too early lol. It doesn’t serve any purpose in there at all other than branding and bowing down to DEA pressure to have it marketed as a schedule III drug instead of II lol

I came from a biochem background originally so it was easier to have it click when laid out the first time

 

[pixies+]

It can be a lot to take in for sure
Not that many people know the ins and outs of it. Feel like most people still think Naloxone is the reason for precipitated withdrawal when taking subs too early lol

I know.. I’ve seen a ton of threads with people asking that question. Although to be fair, I thought the same thing until I got educated about it. That’s how it was explained to me by a doctor. Not sure if it was on purpose to scare me or if he genuinely didn’t know either. I feel the latter. He was passing along info he had been fed.

 

[TombstonePepe]

Given the possible variability of bioavailability of diffrent forms and different roas we have see the mystery. Also we need to look at what if any effect naloxone has in comparison to buepe. Naloxone is touted to have a stronger affinity to bind then other agonists.

Very strong agonists like methadone and bupe can overide the affinity of naloxone.

My Father is an ER dock retired and encountered a methadone suicide attempt that required ALL of the Narcan for multiple hospitals to reverse the methadone OD attempt. She made it, but literally took almost all the narcan from four whole hospitals to push through.


I know the ROA fixation. Is this the reason you are choosing to administer this rout despite negative results?

So I’ve used Suboxone sublingually and nasally. When I use Suboxone (name brand strips) nasally they work a lot quicker and more effectively than sublingually.

When I got my latest refill I was given generic bupe pills. First, I tried taking them the right way (sublingually) and I still felt like shit so I tried them nasally since the Suboxone strips are more effective that way. Well, I felt even worse when I snorted the generic bupe pills. Keep in mind, I was using the same amounts I used with the Suboxone strips.