Where I'm from (Melbourne, Australia) it's been pretty hard to get a hold of bulbs lately, because alot of the supermarkets don't stock them anymore..
I've had them with speed and it's OK, but I'd wait until you've had a night out on a more psychedelic drug, such as MDMA, LSD or mushies (or any combo of these) and then have them.. The difference is AMAZING!!
Then again.. if you can just get bulbs everyday from your supermarket.. go for your life!!!