keeping
Bluelight Crew
so hey this thread was posted quite a while ago and brief survey of google for 'Nitemazepam' brings back no rc vendors. is it available deeper on the web? and has anyone had any exp with it?
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OD Moderators: Keif’ Richards | negrogesic
RCs Nitemazepam (3-Hydroxynimetazepam)
- Thread starter roi
- Start date
gauchoamigo
Greenlighter
That sounds a bit like 'sourcing', which is not permitted under site rules unless in a thread which specifically states is for discussion of various things as received from various places, of which only a couple exist... however, it is not breaking any rule to say that these things are freely available from Chinese manufacturers/synthesisers and on DNMs...
If it were permitted I would LONG ago found a source for the only oxymorphone available outwith the USA, which is the most useless country in the world to try to obtain anything - Ziskas O-MORPHON from Bangladesh. 10mg tablets and 10mg/1mL vials only. Pity the only two really top grade O-M HCls (Endo Opana and Global oxymorphone ER) are strictly confined to that completely impenetrable country!
If it were permitted I would LONG ago found a source for the only oxymorphone available outwith the USA, which is the most useless country in the world to try to obtain anything - Ziskas O-MORPHON from Bangladesh. 10mg tablets and 10mg/1mL vials only. Pity the only two really top grade O-M HCls (Endo Opana and Global oxymorphone ER) are strictly confined to that completely impenetrable country!
THE_REAL_OBLIVION
Bluelight Crew
I just got 75 Lendormins in the mail today....my god...it's the best benzo in the world, probably why its banned in Canada (shh) even if it never was prescribed here. The only other like that is Flubromazepam who god knows why was singled out when there is much stronger stuff around. I had 1 400mg equanil with a 2mg suboxone and I'm feeling like I'm in cloud comfortably numb, saying hi to God on his much bigger cloud, that showoff.
And yeah, I'm prescribed bromazepam 6mg, there's 3mg ones too. In Canada the brandname is Lectopam, 12mg hits the spot, they make 12mg bromazepam pills somewhere, good god, I wish I could find some, it would make it so I wouldn't be out of bromazepam 5-6 days before I need to renew (thankfully I have a large diazepam script that I never run out of nowadays). As for Restoril (temazepam), I'm glad we get capsules with just temazepam in them here, 15mg and 30mg, although I wish they made a 45mg capsule...I might ask my doctor for a switch to my script of 30x30mg temazepam a month to 120x15mg temazepam a month, so I can take 45mg...I hate taking 60mg but, it's the dosage that will make me really doze off, not 30mg, 30mg will make me feel great but that's it, make me very relaxed but not make me want to crawl to bed like when I take a couple 30mg...which sucks because it causes the same problem, I'm always out of them earlier than I should. I guess a middle dose of 45mg would work. My doctor is a very good doctor (Men's Health specialist on top of being a GP), I'm sure he will understand the logic, I will tell him, it's been 2 years since I'm on 30mg prn, but 30mg doesn't work anymore, I don't take more, I wait until I fall asleep otherwise, but right now I feel that 45mg could be a dose we could try?" He knows what I studied in and what my right now useless diploma, as I work in a totally different field, but he knows I know about pharmacology big time, more than him, he admitted they get very little pharmacology classes in med school...that's retarded, you can take more, which he did, which is why he's a pro when it comes to Testosterone issues and other hormones.
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THE_REAL_OBLIVION
Bluelight Crew
It's available in Canada, but nobody markets it, you have to have your doctor send a script to a compound pharmacy, they somehow manage to make 20, 30, 40mg ER pills in a compound pharmacy, no 10mg IR's...of course, at least we have like 8 companies making generic oxycontin that's just like the old stuff, chew away and all that, only one generic company made it hard to chew, you got to crush it, PMS-Oxycodone CR are the culprits. The best ones I tried when I could (before I got on Suboxone), I tried the APO-Oxycodone CR, a 60mg, a Sandoz-Oxycodone CR, a 40mg,a Cobalt Oxycodone-CR 20mg and a PMS-Oxycodone CR 20mg and all of them were exactly like the CDN's except for the PMS, but once crushed and licked on one of my most hated cd's by a band I once liked when they were underground, Blink 182's 1995 album Cheshire Cat, it's my pill crushing surface since a long time heh, i clean it but I crush and eat or snort (I don't snort anything anymore, not even Suboxone...makes it last too shortly), but yeah you get the point, PMS made it hard to chew them, it would be teeth-crushingly hard to do so, they're not like sticky sticky gum like the shitcake called OxyNeos (OP's in Canada), they can be crushed. The only way to do anything with OxyNeos is put them in a can of pepsi or mountain dew or whatever in the fridge for 12 hours, wake up and pour in a glass, it's gonna be there, a white spot which if you touch with your fingers sticks to them, but it defeats the terrible time-release of OxyNeos, which people mostly don't take and get generic oxycontin here because A)OxyNeos are not paid for like OxyContins were by government med insurance B) generics are about 40% cheaper, it's not hard to argue with the price tag with the doctors here. I would be nervous to ask anything that's only approved like Oxymorphone where a compound pharmacy needs to make the pills for you, I was gonna do it with Zaleplon, my favourite Z-drug for sleep, my problem is falling asleep, not waking up when I sleep, once I sleep, I sleep. Zaleplon was perfect for that, I had a script back then of the 10mg yellow capsules with just that in them and snorting the tiny contents worked perfectly, it would put me in a hilarious euphoric mood then lights out. But since I'm already prescribed temazepam by the man, I won't go and ask him for the complicated effort that is faxing a script to a compound pharmacy for something they might not even remember was around, it was sold here as Starnoc for 2 years then bam it was gone, nobody marketing it.
Temazepam is one of the best benzodiazepines. Yes by weight it is not as potent on a WEIGHT basis than a lot of other benzos, but guess what? That means shit. Benzos are and have always been compared to each other solely based on their ability to produce equal anxiolytic effect, similar to how opioids are compared to one another based on equianalgesic effect.
So temazepam 20mg produces the same level of anxiety relief as 0.5mg alprazolam or 0.5mg clonazepam or 10mg of diazepam. But at those doses, temazepam is more hypnotic, sedative, euphoric, relaxing and more recreational all around. There are studies out there, I know of one big study which compared many benzos on their reinforcing abilities. In that mid-80's study, triazolam and temazepam maintained higher rates of self-injection in both human and animal subjects compared to a variety of other benzodiazepines (other examined: diazepam, lorazepam, oxazepam, flurazepam, alprazolam, chlordiazepoxide, clonazepam, nitrazepam, flunitrazepam, bromazepam, and clorazepate). Studies on the pharmacokinetics of various benzos (at least 2, a British study and an Australian one), showed that temazepam was more rapidly absorbed than most other benzos. It's established science that drugs with a more rapid absorption rate are more prone to produce drug-liking and addictive behavior. Triazolam also has a very rapid absorption rate, coincidently.
And outside the North American bubble, temazepam was the most widely abused benzo in Europe, especially the UK. Australia had a major temazepam abuse problem for years. In 1990's and early 2000's, temazepam accounted for most benzodiazepine sought by forgery of prescriptions and through pharmacy burglary. Pharmacists and their staff often encountered aggressive and threatening behaviour from people seeking temazepam. There were 537 burglaries on Victoria's 1200 pharmacies from 1 January to 30 August 2001, including 'ram raids', (using cars to smash through windows). Temazepam was almost always the benzo that was demanded and it appeared to be the main target in many pharmacy burglaries. Temazepam is sought in 85% of all reported benzodiazepine forgeries. As a result of its rampant abuse, the Australian government made a decision to restrict temazepam and put it under a much more restrictive schedule than it previously was (placed alongside barbiturates, potent opioids, etc.). Once physicians stopped prescribing it due to its more restrictive scheduling, abuse rates went down dramatically. In 2004, the Australian government put it back in the same schedule as other benzos, but is not typically prescribed anymore. It's been replaced by zolpidem and other Z-drugs.
The problem with temazepam abuse in the UK in the 80's and 90's was even worse, death due to acute temazepam intoxication and overdose was a frequent occurrence. In 1999, temazepam was implicated in about a third of all drug deaths, either alone or in combination with another downer like alcohol or heroin. The frequency of deaths occurred with the ingestion of temazepam alone was/is of major concern, mainly because a majority of drug users believe that benzodiazepines are not lethal when ingested alone, even in massive quantities. Although most benzodiazepines are considered to have a relatively high therapeutic index and overdose is a rarity, temazepam has consistently been shown to be far more lethal in overdose than other benzodiazepines. Over 10 years in the United Kingdom, 1512 fatal poisonings have been attributed to benzodiazepines with or without alcohol. These were compared with prescription data to establish a fatal toxicity index (deaths per million prescriptions) for each benzodiazepine. Similar indices have been derived for barbiturates and antidepressants. There were clear differences between benzodiazepines. Temazepam by far had the highest number of deaths per million prescriptions at 11.9 (95% confidence interval 10.9 to 12.. ); above that of some tricyclic antidepressants. In contrast, oxazepam had an index of 2.3 (1.2 to 3.4), and the average index for all benzodiazepines combined was 5.7. In the UK temazepam remains highly restricted and placed in Schedule 3 (midazolam and flunitrazepam are also Schedule 3), while all other benzodiazepine are Schedule 4.
Another study, this time in Australia, 303 patients who had ingested a benzodiazepine alone or in combination with alcohol and presented to a general hospital which served a well defined geographical area. Again, oxazepam produced less and temazepam more sedation than other benzodiazepines. Unadjusted odds ratios for coma with oxazepam and temazepam compared with other benzodiazepines.
During 1991-3, 542 patients with benzodiazepine poisoning presented to this hospital, 239 of these patients, however, had ingested either more than one benzodiazepine or coingested other sedating drugs. The drugs ingested by the remainder were temazepam (64), oxazepam (45), diazepam (1 13), clonazepam (24), flunitrazepam (21), nitrazepam (18 ), others Details of coma scores and odds ratios of the benzodiazepines ingested showed that temazepam was significantly more toxic than most other benzodiazepines. Two out of the 45 subjects (4) who ingested oxazepam were stuporous or comatose, 38 out of the 194 subjects (19)who ingested other benzodiazepines (clonazepam, diazepam, flunitrazepam, nitrazepam and others) were stuporous or comatose, while 16 out of the 64 subjects (25) who ingested temazepam were stuporous or comatose. None of the oxazepam subjects were comatose, 16 out of the 194 subjects (who ingested other benzodiazepines were fully comatose, and 9 out of 64 subjects (14) who ingested temazepam were fully comatose.
It's sort of similar to how morphine and heroin are less potent by weight than hydromorphone or oxymorphone, yet heroin/morphine have a higher incidence of, and more profound effects - higher rates of sedation, drowsiness, euphoria, respiratory depression, itchiness, constipation, nausea and vomiting. It's in all the medical literature which physicians follow. When patients have pre-existing respiratory issues or sensitivity to morphines powerful side effects, often hydromorphone is the alternative. In some cases, fentanyl may be more appropriate. Oxymorphone actually has a higher incidence of effects than hydromorphone, but lower than morphine. In terms of cognitive abilities, one study has shown that morphine may have a negative impact on anterograde and retrograde memory, although minor. This does not occur in many of the other potent opioids.
Weight potency has absolutely NOTHING to do with how good a particular drug is.
So temazepam 20mg produces the same level of anxiety relief as 0.5mg alprazolam or 0.5mg clonazepam or 10mg of diazepam. But at those doses, temazepam is more hypnotic, sedative, euphoric, relaxing and more recreational all around. There are studies out there, I know of one big study which compared many benzos on their reinforcing abilities. In that mid-80's study, triazolam and temazepam maintained higher rates of self-injection in both human and animal subjects compared to a variety of other benzodiazepines (other examined: diazepam, lorazepam, oxazepam, flurazepam, alprazolam, chlordiazepoxide, clonazepam, nitrazepam, flunitrazepam, bromazepam, and clorazepate). Studies on the pharmacokinetics of various benzos (at least 2, a British study and an Australian one), showed that temazepam was more rapidly absorbed than most other benzos. It's established science that drugs with a more rapid absorption rate are more prone to produce drug-liking and addictive behavior. Triazolam also has a very rapid absorption rate, coincidently.
And outside the North American bubble, temazepam was the most widely abused benzo in Europe, especially the UK. Australia had a major temazepam abuse problem for years. In 1990's and early 2000's, temazepam accounted for most benzodiazepine sought by forgery of prescriptions and through pharmacy burglary. Pharmacists and their staff often encountered aggressive and threatening behaviour from people seeking temazepam. There were 537 burglaries on Victoria's 1200 pharmacies from 1 January to 30 August 2001, including 'ram raids', (using cars to smash through windows). Temazepam was almost always the benzo that was demanded and it appeared to be the main target in many pharmacy burglaries. Temazepam is sought in 85% of all reported benzodiazepine forgeries. As a result of its rampant abuse, the Australian government made a decision to restrict temazepam and put it under a much more restrictive schedule than it previously was (placed alongside barbiturates, potent opioids, etc.). Once physicians stopped prescribing it due to its more restrictive scheduling, abuse rates went down dramatically. In 2004, the Australian government put it back in the same schedule as other benzos, but is not typically prescribed anymore. It's been replaced by zolpidem and other Z-drugs.
The problem with temazepam abuse in the UK in the 80's and 90's was even worse, death due to acute temazepam intoxication and overdose was a frequent occurrence. In 1999, temazepam was implicated in about a third of all drug deaths, either alone or in combination with another downer like alcohol or heroin. The frequency of deaths occurred with the ingestion of temazepam alone was/is of major concern, mainly because a majority of drug users believe that benzodiazepines are not lethal when ingested alone, even in massive quantities. Although most benzodiazepines are considered to have a relatively high therapeutic index and overdose is a rarity, temazepam has consistently been shown to be far more lethal in overdose than other benzodiazepines. Over 10 years in the United Kingdom, 1512 fatal poisonings have been attributed to benzodiazepines with or without alcohol. These were compared with prescription data to establish a fatal toxicity index (deaths per million prescriptions) for each benzodiazepine. Similar indices have been derived for barbiturates and antidepressants. There were clear differences between benzodiazepines. Temazepam by far had the highest number of deaths per million prescriptions at 11.9 (95% confidence interval 10.9 to 12.. ); above that of some tricyclic antidepressants. In contrast, oxazepam had an index of 2.3 (1.2 to 3.4), and the average index for all benzodiazepines combined was 5.7. In the UK temazepam remains highly restricted and placed in Schedule 3 (midazolam and flunitrazepam are also Schedule 3), while all other benzodiazepine are Schedule 4.
Another study, this time in Australia, 303 patients who had ingested a benzodiazepine alone or in combination with alcohol and presented to a general hospital which served a well defined geographical area. Again, oxazepam produced less and temazepam more sedation than other benzodiazepines. Unadjusted odds ratios for coma with oxazepam and temazepam compared with other benzodiazepines.
During 1991-3, 542 patients with benzodiazepine poisoning presented to this hospital, 239 of these patients, however, had ingested either more than one benzodiazepine or coingested other sedating drugs. The drugs ingested by the remainder were temazepam (64), oxazepam (45), diazepam (1 13), clonazepam (24), flunitrazepam (21), nitrazepam (18 ), others Details of coma scores and odds ratios of the benzodiazepines ingested showed that temazepam was significantly more toxic than most other benzodiazepines. Two out of the 45 subjects (4) who ingested oxazepam were stuporous or comatose, 38 out of the 194 subjects (19)who ingested other benzodiazepines (clonazepam, diazepam, flunitrazepam, nitrazepam and others) were stuporous or comatose, while 16 out of the 64 subjects (25) who ingested temazepam were stuporous or comatose. None of the oxazepam subjects were comatose, 16 out of the 194 subjects (who ingested other benzodiazepines were fully comatose, and 9 out of 64 subjects (14) who ingested temazepam were fully comatose.
It's sort of similar to how morphine and heroin are less potent by weight than hydromorphone or oxymorphone, yet heroin/morphine have a higher incidence of, and more profound effects - higher rates of sedation, drowsiness, euphoria, respiratory depression, itchiness, constipation, nausea and vomiting. It's in all the medical literature which physicians follow. When patients have pre-existing respiratory issues or sensitivity to morphines powerful side effects, often hydromorphone is the alternative. In some cases, fentanyl may be more appropriate. Oxymorphone actually has a higher incidence of effects than hydromorphone, but lower than morphine. In terms of cognitive abilities, one study has shown that morphine may have a negative impact on anterograde and retrograde memory, although minor. This does not occur in many of the other potent opioids.
Weight potency has absolutely NOTHING to do with how good a particular drug is.
Nitemazepam is the 7-nitro instead of 7-chloro temazepam analogue. It should, in theory, be a short-acting benzo (~10-20 hrs), with 2 mg being equivalent to 10 mg diazepam, 0.5 mg alprazolam, 0.25 mg triazolam, 20 mg temazepam, 5 mg nimetazepam, 10 mg nitrazepam, and 0.5 clonazepam
emkee_reinvented
Bluelighter
Temazepam with an nitro attached, wow and I thought it couldn't get any better.
Knowing Temazepam and with no exp with Nimetazepam. This could show very euphoric for a Benzo.
izo
Bluelighter
They say all nitro benzodiazepines are more recreational but it never made much difference for me if I had clonazepam or eg lorazepam…
emkee_reinvented
Bluelighter
morphonorconic
Bluelighter
I remember stumbling across mention of this one about a year ago and thinking I might actually go through the hassle of procuring some and conducting phase (n)one trials.
I hope this will actually BE the Ark of the Covenant RC benzo it’s believed it should be, and NOT another Shroud of Turin overhyped novelty disappointment benzo-like the rest of the RC benzodiazepines.
I hope this will actually BE the Ark of the Covenant RC benzo it’s believed it should be, and NOT another Shroud of Turin overhyped novelty disappointment benzo-like the rest of the RC benzodiazepines.