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New Member With Methadone Issues

Alabasster

Greenlighter
Joined
Jan 6, 2014
Messages
10
Location
Brisbane, Australia
Hi All, You can call me Al if you like. I'm pleased, if not too confident, to be here.

I'll try and keep this brief as I tend to waffle on and lose readers I think. My history mainly involves alcohol and Valium although now I am firmly ensconced in opiate territory. I am 43 years old, with pancreatitis (due to a polypharmacy overdose in 2010) and a painful liver condition that does not involve hepatitis. Currently I am on 100mg of methadone syrup for pain after changing from 16mg of suboxone ended up on after my struggles with valium and codiene (alcohol hos been a non-issue since New Year's Eve 2014). As is common amongst those of our ilk I suffer from anxiety and depression.
Last year I finally beat a seven year valium addiction that caused pancreatic necrosis and ultimately diabetes after an overdose involving valium, alcohol and MANY pills. It was not deliberate, it was not a cry for help it was simply a combination of substance abuse, confusion and high anxiety. It changed my life. Whether for the better (no more booze) or not (pancreatitis, pain, diabetes) is up for debates. Now I have a liver that's giving crazy readings (GGT >1500 no joke), pain and stress.
My liver started playing up just as I finally got off all my anti-depressants, anti-psychotic and beta blocking meds that I had latched onto thinking they would help me get off the valium.....maybe they did. But now I am caught in the methadone web and am, basically, scared out of my wits. The problem (I think) is that I never stabilized properly when I started methadone about 3 months ago as I was Tramadol (Ultram) at the time. You see it began with waking up at 7am (early for me) with a jump and a heart rate that kept climbing until I had my methadone dose. This was weeks and weeks ago and I mistakenly thought it was a depressive episode kicking off again seeing as I'd only quit lexapro, remeron, zyprexa and inderal slowly and carefully over the previous months. Today is my first day on a lower dose of remeron and zyprexa after spending the last week waking at 3am soaked through with sweat, anxious and confused. My psych and I agreed the remeron was too high and not helping (I have been building up to 60mg/night over the last 2 months). Anyway we came to the conclusion that my methadone dose was too low.
About 10 days ago my clinic increased my 'done from 90 to 100mg and this gave me reasonable sleep for only 3 days. It has taken a long time to recover a clear enough head to understand I never stabilized on 'done and have suffered needlessly for weeks. You see I am very anxious about increasing my methadone because I know one day I will want to come off it and all I've read is how horrible that process is.
Anyway, tomorrow I'm going for metabolism blood tests (2) to see if my dose is being processed too fast by my liver. Hopefully I'll get some answers and be able to tackle the issue with my clinic. I am wonder a few things though. Would splitting my dose of 100mg solve the problem? (I'm doubtful) Could it really be as simple as increasing my dose until I'm stable for a week or so? How can I make those early hours before I get my dose tolerable because it is the WORST way to wake up? and finally, Won't I just adjust to the higher dose and end up in the same position therefore starting a vicious cycle???
If there is anyone left after my rant, thanks for reading and thanks especially if you were able to offer any advice. I look forward to being a part of this community and I hope my loooong message hasn't been too painful.
 
Now that you mention it Capt. Heroin I have used very low doses of valium (2-4mg) for short periods of time over the last few months. I kept it very low and only for a short period of time (12 days at 2mgs was the longest phase) to help me get off Tramadol, and for a few days a couple of other times. Could this be enough to trigger withdrawals? These symptoms are a bit different to the usual benzo withdrawals as they're not as intense, no muscle spasms as such and no wild confusion. I just had a period where I took 15mgs on the middle Saturday night of a fortnight and that's it, so I thought it can't be valium. If it is so be it. I'll go back on a stabilising dose and ween of slowly again, but when I do take valium it does not really calm me but rather makes me feel very depressed (weird stomach) and still a bit anxious.
The not knowing is killing me. I'm not taking to the mirtazapine and zyprexa well at all with waking up soaked through with sweat and muscle pains and anxiety most nights especially when I was on 60mg mirt. I'm scared and have started looking at suicide information online when it's at it's worst. I do know that valium withdrawals can make you super sensitive to other meds so maybe this is the problem.
Like I said I scared, very scared. ANY advice on narrowing down this/these problems so I can tackle it would be hugely appreciated. I'm seeing my Psychiatrist in two days and am thinking about taking 15mg valium/day until I see him but I don't want to make the situation any worse. Also, I'm thinking about asking for Seroquel as a symptomatic anxiolytic and reducing the Zyprexa as I have a suspicion the Zyprexa combined with mirtazipine may be causing a serotonin syndrome type issue. You see? I'm so confused!!!
 
Me again. I have some baclofen 10mg tablets left over from my dependency days because I heard it can help with benzo withdrawals. Should I take a couple of those each day until I see the doc? In the past they put on a really positive buzz.
 
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It might be the Zyprexa and mirtazapine. Do you have the side effects lists for your medications?

I don't think 2mg of diazepam for less than 2 weeks should cause any problems for you <3

I am not sure if baclofen would help or not.

feel free to post in Basic Drug Discussion or Other Drugs to see if other members can help <3
 
Hi Capt H,

Thanks for caring man, it helps and means a lot at the moment as it seems my family doesn't understand, my Psych is frustrated and just wants me out of his office and my normal doctor is just plain out of her depth. You're a support for me no matter how little it is, you take the time AND understand. ;0)

I'm starting to get VERY suspicious about the Zyprexa as it's s/e profile is very similar to my current ordeals ie; excessive sweating, insomnia, anxiety, muscle pain and tension and increased heart-rate. For that matter the Mirtazipine s/e s are not too different. My psych said to stay on Mirt 30mg/night only, Olanz 5mg night and morn, propanolol 20mg when I have my anxiety issues at 4am. This morning the Propanolol made the anxiety worse and increased the muscle tension/pain significantly, and the Olanz definitely increased sweating and anxiety. I read on webmd.com (I think) that there is a serotonergic (?) interaction between Mirt and Olanz that can lead to serotonin syndrome. Tonight I think I'll reduce my olanz to 2.5 at night and whatever in the morning, not much of a reduction at all.

Also, I am curious as to why my methadone dose did nothing for my anxiety yesterday but shut it down completely today. There has to be another factor at play. AND I've been taking approx 5mg Valium every second day for the last 6 days and I'm worried about triggering dependence there.

Anyway, do I have to start again in another discussion or is there a way to shift this whole thread?
 
Hi and welcome to Bluelight :)
^ I found methadone to be a drug with varying effects. (IME)
sometimes I'd take 10 mg (no tolerance) and feel good for all day, last time I took 20 mg (always no tlerance) and I barely felt it if at all.

it would be best to start a discussion in the appropriate sub-forum imho so you can get more responses :)
 
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