Opioids Need Help witha med regime

[XTc_for_me]

Alright, a little background : I started eating lortabs, and they were working fine, but as i found stronger stuff, i would do it also, wich included suboxone,(wich still tore my world up after just doing tabs) percs, roxi/oldschool oxy 80's, methadone, opana 20 ers(oldschool), hydromorphone, and morphine 60's, i always snorted/ate them.

Then i got ahold of some powder heroin from chicago, and had about 10 bags, and was introduced to IV... then i got to were i wanted nothing but the morphine/roxi/hydromorph and started IVing them full time, cause it was the closest the the heroin, which i loved..., in total ive been on pain meds 6 years, and around 2 years of it being mainy iv morphine and roxi's and hydromorph, anyways, suboxone does nothing for me but make me feel normal, i usually do 3 60 mg morphine a day or more if i can (IV), I have used my own little recipe for coming off, i get one 8 mg strip and cut it into 5 pieces, and take 1 piece a day, and then stop, it is fairly uncomfortable but nothing i cant handle, but after the sub i still feel off, Now i also have these meds for when the sub is gone )pretty much unlimited on all of them for the 2-5 days i should take them, to come down a little smoother....

In my arsenal i have:
Gabapentin: 300 mg caps - take 4 in morning and 4 at night
lopermide: 2 mg caps - i take 10-15 in the morning and 10 at night
baclofen: 10 mg tabs - take 2 in the morning and 2 at night
Ibuprofen: 800 mg tabs - take 1 in morning and 1 at night
clonidine .01 mg tabs - usually 1 at night, sometimes 2
Amitryptiline : 50 mg tabs (kind of make my rls worse, so i take a half of one, or quarter one at night)


My actual question is, How many of each should i take of the above meds, and how many times a day for a little relief.... i will only do it for 3 or 4 days relistically, wich should be plenty of times for most acute withdraws to be gone especially after 5 days of sub, and waiting for the paws... oh joy

thanks in advance, and i am pretty sure this was the right forum to post in, if not sorry, and please move were acceptable.

*edit* This is all off the streets, never seen a dr for anything like this...if it matters..? I have also relapsed and got off using this same combo of sub/ other meds after my binges, but i want a 2nd opinion on dosages i should take , to see if im about on track or if i could do more, for a little more relief.

 

[tricomb]

Related Reading

I thought this might be of some use to you.

 

[XTc_for_me]

Thank you, i did not do any searches, i will go over that thread..... feel free to close this if you think its appropriate?


well i checked it out, it seems to talk about the meds, but not really about the dosages, i guess i have it down pat, i come off fairly smooth, just wanted to make it a tad bit smoother...

 

[tricomb]

Nah man you can keep this thread open in case you get some better, more specific replies

I know it might not be possible but if it is, the best way to get off buprenorphine is by commencing a taper, anything at all is better than stopping cold turkey.

 

[mellowyellows]

The Gabapentin will help with anxiety, depression, and some muscle/head pain. The Ibuprofen helps a little with muscle/head pain as well.

 

[Sepher]

How much Clonidine you got available XTc? If you're finding symptoms are severe taking it more often than the once nightly you mentioned should be a big help. Doses as high as 1.2mg / day are quite often prescribed for acute opiate withdrawal. Depending on severity of symptoms you might find 0.4mg / day is enough.

I'd start at a low dose of 0.1mg 3-4 times a day to start on day 1, building dose in small increments up to 0.2 or even 0.3 3-4 times a day at peak withdrawal. Can't remember if I ever went as high as 1mg / day. Probably not cos it crashed my blood pressure a bit too much, to the verge of blackout when I stood up too fast. If you find that happening to you skip a dose and / or cut your dose back. You just have to trial and error it to an extent, any noticeable effect on blood pressure dictating what your limit is. It's a delicate balance, so err on the side of caution.

It's important you taper dose over at least 4 days once you've hit peak withdrawal and are coming out the backside of it to prevent rebound hypertension when you stop taking it. Jump off point wants to be 0.1mg / day or less.

Important note: Quick Google suggests there can be a potentially serious interaction between Amitriptyline and Clonidine. I can't claim to understand it, or in what circumstances the interaction could become an issue. If you're inclined to try the above dosing regime with Clonidine, maybe drop the Amitriptyline to be on the safe side. It might be that the Clonidine does more for you anyways.

Best of luck! Hang in there man, you can do it.

 

[XTc_for_me]

Thanks everyone, I wasnt aware amitriptyline would interact with clonidine

yesterday (friday) was the last dose of sub. i took, and last night i took 4 of the gabapentin, 1 baclofen, and 10 lopermide, i didnt take any clonidine or amitriptyline because the sub was still helpin, for sleep that night,

anyways i went to bed and didnt wake up untill 7 pm (slept for 21 hours)and felt high as a kite off the gabapentin i guess, i missed work and everything, i thought it was 7 in the morning, i got up and got ready, and went outside and thought it looked really weird for 7 am, i thought a bad storm was comin, cause there were dark clouds every were and it was getting dark.....,

i still didnt realize it untill my dad told me it was 7pm i didnt know what was going on.... but i do know i felt very good when i woke up... its 2 am now sunday morning..

. i have taken another dose of the gaba, lop, and baclofen and an 800 ibprophen.... i dont think ill even need the amytriptyline or clonidine, ill know when i go to lay down if i get rls, ill pop a clondine, and i guess ill save the amitriptyline for any other relapses after i run out of clonidine lol

I havnt taken any cloniidine during the day because i havnt been having any hot flashes, or sweating... i think ill stop all meds, and see how i feel tomorrow ...i think i have this one beat..... now if i can just stop going back for more ill be good


It is so weird how every withdraw is different, sometimes i suffer, even with the sub and other meds, but this time it i barely feel like im withdrawing, even though i was going at it and showing those morphine pills who's boss.

 

[Znegative]

I'm glad your kick is going easy so far.

For loperamide I find personally 40mg is enough to take me out of withdrawals (though lower dosages could be used I'm sure, especially in combination with cimetidine (Tagamet), and from what I've heard large ammounts of black pepper). Honestly Ove found higher dosages more benificial (80+mg), though I wouldn't recomend long term usage of such high dosages due to possible toxicity issues. But I've found 100-120mg can easily hold withdrawals at bay for at least 24 hours, and though there is a debate as to whether Loperamide can cross the BBB, I do believe from personal experience that it is capable of some CNS opioid effects, though they are not anything to write home about (I.E. loperamide is not recreational), though it can help reduce cravings.

Gabapentin (Neurontin) is a miracle drug for opiate withdrawal IME, far superior to benzodiazepines in terms of efficacy and because the likelihood of dependency after short term usage is far less likely than it is with Benzodiazpine's. If you're going to use gabapentin, I would start off with a Lowish dosage, no more than 600mg. Starting off with dosages over 1g is going to backfire, because while it may work well the first day, tolerance to this drug works up like no other, and the more you take, the less is absorbed. 300mg shoud be enough to provide adequate reliefe from many withdrawal symptoms, and you can probably get away with dosing only 2, maybe 3x/day.

I would use the clonidine sparingly, perhaps before bed.

All in all, I would try and use gabapentin primarily, followed by loperamide. I have no experience with baclofen, though I imagine it would be no more, probably less effective than Gabapentin. The one interesting thing about Baclofen is that there have been study's which show that Baclofen slows down drug Users impulse control.