nausea and 5htp postloads

[Numeron]

Ive heard a lot about 5htp recently, and done plenty of research on the apparent effects of pre and post loading in an effort to minimise the comedown. As a result im pretty sure I have all my answers questioned as far as dosages and times etc, and i intend to order a bottle to trial sometime soon.

My problem is thus:

(taken from aus drug discussion faq concerning pre/post loading with lots of different stuff)

Nausea is most probably related to the increase in serotonin levels. Serotonin syndrome is the result of excessively high serotonin levels and is partially characterized by nausea. This is NOT to say that if you get sick from rolling you are experiencing serotonin syndrome. Rather, that every person's biochemistry is unique and that biochemistry/neurochemistry is infinitely more complex than just three or four major neurochemicals at work. So, the point being, different people may have different reactions to the same chemicals, the only variable being their individual biochemistry/reaction and not necessarily the chemical itself. Nausea is not necessarily a bad sign, but could underscore that the concentration of MDMA / serotonin / etc. is too high in one's bloodstream (i.e. individual biochemistry/metabolism is more effective )and simply a sign to take less.

My girlfriend and her friend typically feel quite nauseous after taking pills. I can occasionaly feel it a bit myself, but I may just be picking up the vibe from them. This doesnt really occur as a part of the comedown (although it can) rather around T + 3 hours, or half-ish way through plateu. Dropping another pill generally gives the usual ecstasy effect, but the nausea seems to stick. We've never been particularly worried about it or anything and we'll probably continue to not worry since there are no other adverse effects and its always been like that for years past... hey, these things just happen with some people, but perhaps strong pills leading to a slight overload of seretonin is the cause.

Does this mean that post-loading 5htp in the early morning before bed or a couple of hours after arriving at a recovery party make it worse as a result of loading more seretonin in? or is it more likely the nausea is just something else? Im happy to jump onto 5htp myself to see if it does me any good, but for girls who are guaranteed to throw up once or twice at the end of a night on the pills im not so sure. I dont want to make them worse... but then again if the nausea is from some kind of lack of seretonin then it could be the cure for a lot of painful mornings.

 

[kittymeow]

5-HTP can be broken down in your liver and that is what causes the nausea.

I've experienced it before and actually spewed off too much 5-HTP. That could be because I generally don't come down as hard as others and possibly use up less of my serotonin.

Also, I generally puke on strong pills too (eep its a hard life hehee).

My advice is to start on a lower dosage. When all my friends were taking 200mg it was making me sick, so I went down to 100mg and felt heaps better. And once you've figured out how much is just right, don't take more than that in a day. Remember as with all chemicals, you can always take more, but you can't take back what you've already swallowed.
Hope I've helped some

EDIT: Checked my facts at Wiki http://en.wikipedia.org/wiki/5-HTP

 

[Numeron]

actually neither me nor my girl have had any yet. She gets the nausea without it, I was wondering if having any at all would just make it worse?

 

[quiet roar]

I get nausea if I take them on an empty stomach: with food, no problem.