I have a very odd liver. I've never been able to handle alcohol in any amount (two beers and I get nauseous), but I've always had a very strong tolerance to most prescription medications. Methylphenidate, Cocaine, Alprazolam, Oxycodone, Zoloft, Mirtazapine, Abilify, even Diphenhydramine...I've always been able to tolerate very high doses of them, and I also pass through the half life of most meds much quicker than the meds stated half-life. I know functioning alcoholics who can blast through a case of beer like it's fruit punch, but they take two Benadryl pills and they can't get up the next morning. Go figure.