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  • BDD Moderators: Keif’ Richards

Natural tolerance to oxycodone or too weak a dose?

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kyle627

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Aug 23, 2011
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got my hands on some 5mg percs, the first time i did it i popped 1 and then another about an hour later, the second time i popped 2, then blazed and i only felt the weed. so both times i felt barely anything

now i popped both at once and railed a very small line so probably only about half of a quarter of a pill.

i feel slightly numb, but thats it. no euphoric feeling or anything i have never done pills so i have no tolerance, im scared to take 15 mg for fear of getting sick but i dont feel anything from 10, any advice?
 
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ik wat your saying and pop 2, wait for effect (10-15 min) no effect, take 2 more! or one more.
i have been on many PK's (pain killers) and perc is a fairly hard one to get an effect outta because of the Acetominophen, oxy you can snort, perc you cant although theyr the same drug.
-chew them up and drink water
-take a higher dose
-dont take too much, i took 5-7.5s on ritalin and had a numbing effect plus a great feeling, but didnt think they were working and the rit wore off and i was so messed up all nite and couldnt eat till i smoked a bowl and was sick till i smoked
enjoy yer buzz!
 
Some people just have a natural high tolerance & this could be you or it may just be that you need to up your dose next time to 15mgs. Dont add anymore tonight.
 
TheLostBoys said:
Some people just have a natural high tolerance & this could be you or it may just be that you need to up your dose next time to 15mgs. Dont add anymore tonight.
Click to expand...

This..

In which case you may want to do as Captain Heroin suggests. Otherwise, if you do increase your dose and start taking more than 9 Percocets at once you will need to aquaint yourself with a cold water extraction (CWE) to remove the APAP so it doesn't ruin your liver (see link in my sig) :)

While taking another one tonight probably wouldn't kill you, it won't give you an accurate gauge for your dose and it is very wise to be cautious with strong opioids such as oxycodone. I'd try again with 15mg another night if you wish to :)
 
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High natural tolerance, i'd say. There's a wide variation in sensitivity to opiates. Some people need 3 percs with no tolerance to get anything, I can't take much more than half of a perc 5 without feeling nauseous; half of a perc 5 is good for me (that's by far the highest sensitivity to opiates that i've heard reports of, btw).

Effie, current FDA guidelines are to limit APAP consumption to not more than 4000mg/day (though i thought i remembered hearing that it was being revised down to 3000mg/day). perc's contain 325mg of apap each, so you could take up to 9 in a day while staying within the 3000mg/day limit. You don't want to be near the APAP limit every day, for sure, but you don't need to CWE for an occasional dose that's below that limit.
 
Oh yeah haha was being dozy and thinking of doses of UK pills which have 500mg each, so each dose is 1g.. only just woke up ;)

I'd heard about the FDA 3000mg thing before but haven't looked into it myself, in the UK it is still 4000mg. I'd be intersted in knowing their reasoning for dropping it, if there is any new evidence out etc..

Will edit my post, good catch thank you :)
 
If one has a healthy liver and is in generally good health, he or she can go to 4 grams (the old FDA limit) once in a while without hurting anything. Do it every week and you will fuck the body up, though. With Norcos (5,7.5,10mg of hydrocodone/ 325mg APAP) and Percocet (5, 7.5, 10mg oxycodone/ 325mg APAP) you can take up to 12 pills in a day.

In a single, dose, though, I wouldn't go over 2/3 the daily limit (and then I wouldn't take any more for the rest of the day) so that your liver can process that huge amount of APAP. Even doing the daily limit all at once is bad, so that's why I say, max 2700 milligrams of APAP at once, ever. Don't go over that amount. That is 8 pills if they are xx/325mg APAP.

To directly answer your question, take 3 or 4 at once if you aren't getting pain relief from 1 or 2.
 
maybe try and drink a beer or two, i love drinking a few beers on any opiates.

i would try what everyone has said, but i wouldnt recommend to keep upping the dose again and again untill you finally feel something. maybe Percs are not for you, maybe try a different pharmaceutical? But respect pills cause the addiction can sneak up on you. Ive seen it happen tooo many times haha
Be safe : )
 
I would try to feel it first to determine your normal dose before combining it with drugs that will potentiate it (such as alcohol)
 
I agree ^ I should have been a little more clear. I would also suggest finding a standard dose before drinking beer, if you dont have a any tolerance to alcohol, one beer could be too much. All though I love the combo of a beer or two and some opiates, it's not for everyone.
 
muvolution said:
In a single, dose, though, I wouldn't go over 2/3 the daily limit (and then I wouldn't take any more for the rest of the day) so that your liver can process that huge amount of APAP. Even doing the daily limit all at once is bad, so that's why I say, max 2700 milligrams of APAP at once, ever. Don't go over that amount. That is 8 pills if they are xx/325mg APAP.

To directly answer your question, take 3 or 4 at once if you aren't getting pain relief from 1 or 2.
Click to expand...

I've often wondered about what a safe single dose is. Here the recommended max dose is 1000mg every 4-6 hours so I wouldn't want to be taking more than that. Maybe that was what I was thinking of when I said no more than 3 Percocets, it was 6.30am here, hah.. I certainly would feel uncomfortable going over that myself but I'm not sure what the risks are of going higher.

It all depends on the state of your liver, I suppose..
 
I've definitely noticed a difference depending on how full my stomach is, to the point where I will delay meals ridiculously to make sure I have an empty stomach, hah.. more with DHC but also with oxy. Same amount of drug is absorbed but in a more drawn out way.
 
also i forgot to add, whenever i take them i pop them usually within minutes of a meal, for fear of getting sick from taking them on an empty stomach.

should i try and take them a few hours after my last meal next time?

because i gave 2 to my friend and he popped them and said he felt great and they worked, and he does alot more pills then me, same thing with my friends uncle 2 worked nicely for him, and i dont think they were as concerned as me so they definetely werent eating before taking them.

could this be my issue, not a "natural tolerance"?
 
yeah, take them between meals, not with a meal. if you do get sick, you won't have anything to throw up anyways, which is much better than losing your dinner.

Try 2 this way, maybe 2 1/2. If that doesn't work, add 5mgs and try again.

Remember, use the smallest amount possible to achieve the effects you are looking for since any excess will just raise your tolerance.
 
go for 20mg of oxy. you wont die, you wont go to the hospital, you'll either get pretty high or not at all. if not at all dont bother with these lil percs.
 
For some people with low natural tolerance 20mg would be uncomfortable and too much. As 10mg did nothing this is unlikely, but better to be safe than sorry so I'd try 15mg first, on an empty stomach. Or even 10mg on an empty stomach to be extra-cautious, as you've only tried it right after eating.

I think your question has been answered pretty thoroughly in this thread now so I'm going to close it.. Shoot me a pm if you have any questions though :)
 
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