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Naphthylisopropylamine

Reminisant B said:
http://en.wikipedia.org/wiki/Naphthylisopropylamine

Anyone know any more info on this chemical?

it can be looked upon as sort of an IAP type chem, although two benzene rings.

wonder if it has beta-adrenergic activity - similar to propranol but less antagonistic looking (not scientific but someone might be able to explain it better.
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there are several papers relating to this and I think even a thread on here (around the start of this year I think) it has been researched as a cocaine treatment. when I find the thread I'll let you know. I believe the researchers were working on the hypothesis that addictiveness is more closely correlated to NE rather than DE
its mentioned in the stims of the future megathread
http://www.bluelight.ru/vb/showthread.php?t=271982&highlight=pal+287

its rather unlikely to have propanolol like effects because of the distance between the nitrogen and the benzene and the lack of a hydroxyl group.
 
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No real surprise. This is the psychedelic "G" with all of the ring substitutions removed (except for the isopropylamine). Take any DOx and do the same thing....and you get amphetamine.
 
and if you take any 2-c and magically remove all the ring substituents bar the ethylamine you get phenethylamine...
what am I not seeing?
 
vecktor said:
I believe the researchers were working on the hypothesis that addictiveness is more closely correlated to NE rather than DE
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Well that's an obvious load of crap, but I guess they'll probably find that out for themselves.

Edit -- depends on how you define addiction, maybe... NE never sent anyone on a 72-hour run, but maybe cravings/urges in between are more related to NE than dopamine.
 
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No real surprise. This is the psychedelic "G" with all of the ring substitutions removed (except for the isopropylamine).
Click to expand...

Technically the second aromatic ring is a ring sibstitutuion compared with phenethylamine. Removinbg the 2,5-methoxy groups would have been a correct analogy (& if you do that to other phenethylamines you don't end up with PEA/amphetamine, but a variety of different drugs eg PMA from TMA-2, 4-MTA from DOT/aleph-1 etc)
 
Ah, alpha-methyl-(napthyl-phenethylamine)...amnapthamine anyone? This one is Rothman's baby. I think that it has a high potential of being a good substitute for methamphetamine, or (perhaps even more so) cocaine in cases of dependence. However, Rothman might be a little too focused on 5-HT and contrary to his belief, something already on the market, like phendimetrazine (which is really just super extended-release phenmetrazine) might work well as a 'quasi-amphetamine' medication.

The interesting thing about this one is that it manifests little to no fenfluramine/MDMA-esque neurotoxicity, despite being essentially a 3,4-alkyl substituted amphetamine.
 
pardon my ignroance and outdated models, but isn't a major action of amphetamines uptake into the NE vesicles, causing release of NE, which then stimulates DE release and uptake inhibition of both DE and NE?
 
morninggloryseed said:
No real surprise. This is the psychedelic "G" with all of the ring substitutions removed (except for the isopropylamine). Take any DOx and do the same thing....and you get amphetamine.
Click to expand...

Any predictions on whether this would therefore have psycadelic / 5ht2a effects (or side effects depending on intended use) ?

Also never read of it being controlled, I guess it might be covered by PEA catch all clause. ?
 
Reminisant B said:
Any predictions on whether this would therefore have psycadelic / 5ht2a effects (or side effects depending on intended use) ?

Also never read of it being controlled, I guess it might be covered by PEA catch all clause. ?
Click to expand...

no psychedelic or 5ht2a effects are expected, the distant relationship it has to G-N the amphetamine version of 2C-GN is not going to do much.

it appears to be a NE and DA reuptake inhibitor with some other effects that is confusing the rats

the the napthylisoproplylamine is UK legal (it isn't derived from amphetamine and it doesn't have methoxy or halo substitutions in the ring) also it isn't caught by Les Kings' shoddy cut n paste of the Pihkal index, because it isn't in the index.
I have no idea about the rest of the world
 
I have some pal-287, have tested it a little ( a very small amount insufliated(1-2mg) and roughly 2-4mg vaped. The effects I felt were similar to mdpv without the ridiculous amount of stimulation.

Please note; I have little experience with stimulants, mdpv being my 1st experience and even that has it's limitation to 3 experiences.

I know that vaporizing a new chemical is not very safe, bad judgement on my part.

Is it probable that heat could modify this substance into something else?

Edit: posted in wrong topic! meant to post here ---> http://www.bluelight.ru/vb/showthread.php?t=481463&page=2
 
Those are really low doses... this one's supposed to be down in potency from amphetamine. My guess is that the oral activity threshold is around the 10-15mg mark from the EC50 values with a fully active dose between 20-60mg, but as with everything, proceed slowly.
 
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Yeah, I too was wondering about the dosage range as I have some at my disposal. It sounds like a better idea to try it orally. Yesterday I did an allergy test. Today I will try it at 5 mg first, then 10, then 20. If it's weaker than amphetamine, I don't imagine I'll start to really feel it until it gets to the 40mg mark or so.
 
I know you are not allowed to post sources openly on BL but if anybody knows of where this RC can be obtained then please send me a PM.
 
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