• N&PD Moderators: Skorpio

N-methyl-4-methyl-phenethylamine???

DMTime_warp

Bluelighter
Joined
Aug 27, 2006
Messages
41
Iv'e been trying to find some form of documentation on this compound but can't. I am mainly curious if it would be active and if it is would it be enjoyable?:\
 
As one of the primary routes of metabolism had chance to be via 4-hydroxylation, I don't think downing huge amounts of said compound a la phenethylamine would be a good idea. 4-methyl groups without a couple of methoxy groups (2,5 or 3,5 substitution pattern) in addition just don't strike me as being something I'd consider ingesting
 
^^^ F&B, I'm a little slow, but... are the methoxy groups what make it hard for the compound to be chewed up by the enzyme? Like, the shape just ain't so great anymore?
 
Yeah I had a feeling it wouldn't be, but im sure it would be if it had a methyl on the beta, probably crappy though since chances are it would only effect dopamine so much as it would serotonin. Im guessing the Beta-methyl one would be extremeley nuerotoxic seeing as what iv'e read about beta-methyl-phenethylamine it has MAOI properties. Probably a more interesting set of compounds worth trying would be the 2-aminotetralines, they look kinda tasty.
 
No they give an alternative site for metabolism (removal of a methyl group of a methoxy to leave a phenolic group - much more polar). The also make for a much more interesying compound (eg 4-methylamphetamine becomes DOM)


iv'e read about beta-methyl-phenethylamine it has MAOI properties. Probably a more interesting set of compounds worth trying would be the 2-aminotetralines, they look kinda tasty

It's a weak competetive inhibitor in the same way amphetamine is, nowhere near the sort of inhibitory activity as harmala alkaloids (competetive) or phenethylhydrazine compounds (non-competetive). From what I've read & seen about unofficial human trials concerning 2-aminotetralins, they are rather toxic creatures (BP all over ther place etc)
 
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Oh, iv'e only read about a couple trials on mice. Man, I wan't something new and different aside from the common phenethylamines and tryptamines. MDPV looked good, but I already have a panic disorder and from other peoples experiences that I read it has caused severe panic on the comedown. I mainly want a short acting stimulating empathogen but not one that is so strong and good that I want to keep taking more(mephedrone) the last thing I need is to get addicted to something or go on a binge.
 
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