Foreigner
Bluelighter
There are some unanswered questions about MXE/Ketamine comparisons on the internet. I think this is due to MXE being a relatively new substance.
The empirical defining differences between MXE and ketamine are the dosing level and the length of the high. MXE is active at lower doses and the high lasts significantly longer than ketamine. Other comparisons are more subjective (listed below), but may still prove useful.
This thread assumes that you are dealing with one or the other, not both mixed together or with any other adulterants. Missing info is labeled accordingly below. Please do not assume it is complete or correct, I am posting it here for discussion. This OP will be edited as more accurate info is gathered.
Taste:
MXE - metallic, micro-doses under tongue more likely to numb mouth; some say it is more aromatic ("perfume"-like quality)
Ketamine - bitter, cold, minty, hairspray-like taste
Dose:
Ketamine - 20mg = threshold
MXE - 20mg = you're high
Ketamine - 5mg = usually very minor effects
MXE - 5mg = high can be felt, and is lasting
Length of high:
Ketamine - 1 hour with 1-3 hour after effect
MXE - 2-4 hours with after effects lasting days
- more people report an extended hangover effect from MXE than ketamine, but negative after effects are possible with both
Common forms:
Ketamine - crystal or powder
MXE - almost always powder
- ketamine is usually derived from evaporating its liquid state until solid crystals are left behind; MXE is never in a liquid state and thus is universally in powder form
Colour:
Ketamine - white
MXE - white, or off white-tan
Effects:
MXE - motor function impaired but movement possible, even at higher doses; some people report being able to move during an m-hole
Ketamine - less motor function, even ataxia, movement impossible in a k-hole
Burn test:
Ketamine - burns to an oily red
MXE - ?
Dissolvability in water @ standard pressure, and room temperature:
Ketamine - 150mg/ml max
MXE - 150mg/ml max
- both require the addition of heat for complete dissolution
Heavier doses:
Ketamine - can k-hole completely
MXE - m-hole not guaranteed, some people achieve it while others can't
Other:
- both drugs share cross-tolerance (if you become tolerant to one you will become tolerant to the other)
- both are NMDA antagonists and non-competitive allosteric modulators, but MXE acts as a reuptake inhibitor of serotonin which accounts for subjective reports of it feeling warmer than ketamine
- the warmth felt from either can be due to less ion channel blockage (i.e. you simply feel the cold less), or from reuptake activity similar to classical anti-depressants (a feature more strong in MXE)
- overdosing on ketamine is rare, but on MXE it's possible due to equivalent amounts of MXE producing a more drastic, longer lasting high
- both can generate spiritual experiences, but subjective reports say that ketamine highs tend to be more lucid and stable than MXE
Please feel free to post more experiences or empirical knowledge, and I will update this post accordingly.
The empirical defining differences between MXE and ketamine are the dosing level and the length of the high. MXE is active at lower doses and the high lasts significantly longer than ketamine. Other comparisons are more subjective (listed below), but may still prove useful.
This thread assumes that you are dealing with one or the other, not both mixed together or with any other adulterants. Missing info is labeled accordingly below. Please do not assume it is complete or correct, I am posting it here for discussion. This OP will be edited as more accurate info is gathered.
Taste:
MXE - metallic, micro-doses under tongue more likely to numb mouth; some say it is more aromatic ("perfume"-like quality)
Ketamine - bitter, cold, minty, hairspray-like taste
Dose:
Ketamine - 20mg = threshold
MXE - 20mg = you're high
Ketamine - 5mg = usually very minor effects
MXE - 5mg = high can be felt, and is lasting
Length of high:
Ketamine - 1 hour with 1-3 hour after effect
MXE - 2-4 hours with after effects lasting days
- more people report an extended hangover effect from MXE than ketamine, but negative after effects are possible with both
Common forms:
Ketamine - crystal or powder
MXE - almost always powder
- ketamine is usually derived from evaporating its liquid state until solid crystals are left behind; MXE is never in a liquid state and thus is universally in powder form
Colour:
Ketamine - white
MXE - white, or off white-tan
Effects:
MXE - motor function impaired but movement possible, even at higher doses; some people report being able to move during an m-hole
Ketamine - less motor function, even ataxia, movement impossible in a k-hole
Burn test:
Ketamine - burns to an oily red
MXE - ?
Dissolvability in water @ standard pressure, and room temperature:
Ketamine - 150mg/ml max
MXE - 150mg/ml max
- both require the addition of heat for complete dissolution
Heavier doses:
Ketamine - can k-hole completely
MXE - m-hole not guaranteed, some people achieve it while others can't
Other:
- both drugs share cross-tolerance (if you become tolerant to one you will become tolerant to the other)
- both are NMDA antagonists and non-competitive allosteric modulators, but MXE acts as a reuptake inhibitor of serotonin which accounts for subjective reports of it feeling warmer than ketamine
- the warmth felt from either can be due to less ion channel blockage (i.e. you simply feel the cold less), or from reuptake activity similar to classical anti-depressants (a feature more strong in MXE)
- overdosing on ketamine is rare, but on MXE it's possible due to equivalent amounts of MXE producing a more drastic, longer lasting high
- both can generate spiritual experiences, but subjective reports say that ketamine highs tend to be more lucid and stable than MXE
Please feel free to post more experiences or empirical knowledge, and I will update this post accordingly.
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