okay, so now i know for a fact mxe every single time makes me suddenly have to poop. and its not like an inkling, its like a rumbling, lol. now dont get all grossed out...it doesnt give me the squirts ever, its always the most healthiest of dumps. but every single time i dose, especially nasally for some reason, i get the stomach sensations about 15 minutes in or so. nothing to complain about, in fact i think it helps keep me regular! but i just find it to be strange indeed!